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dc.contributor.authorUlloque-Badaracco, Juan R.
dc.contributor.authorAlarcon-Braga, Esteban A.
dc.contributor.authorHernandez-Bustamante, Enrique A.
dc.contributor.authorAl-kassab-Córdova, Ali
dc.contributor.authorMosquera-Rojas, Melany D.
dc.contributor.authorUlloque-Badaracco, Ricardo R.
dc.contributor.authorHuayta-Cortez, Miguel A.
dc.contributor.authorMaita-Arauco, Sherelym H.
dc.contributor.authorHerrera-Añazco, Percy
dc.contributor.authorBenites-Zapata, Vicente A.
dc.date.accessioned2022-09-08T23:40:38Z
dc.date.available2022-09-08T23:40:38Z
dc.date.issued2022-08-01
dc.identifier.doi10.3390/tropicalmed7080150
dc.identifier.urihttp://hdl.handle.net/10757/660928
dc.description.abstractFibrinogen-to-albumin ratio (FAR) and blood urea nitrogen-to-albumin ratio (BAR) are inflammatory biomarkers that have been associated with clinical outcomes of multiple diseases. The objective of this study is to evaluate the association of these biomarkers with the severity and mortality of COVID-19 patients. A systematic search was performed in five databases. Observational studies that reported the association between FAR and BAR values with the severity and mortality of COVID-19 patients were included. Random-effects models were used for meta-analyses, and effects were expressed as Odds Ratio (OR) and their 95% confidence intervals (CI). Publication bias was assessed using the Begg test, while the quality assessment was assessed using the Newcastle Ottawa Scale. A total of 21 studies (n = 7949) were included. High FAR values were associated with a higher risk of severity (OR: 2.41; 95% CI 1.41–4.12; p < 0.001) and mortality (OR: 2.05; 95% CI 1.66–2.54; p < 0.001). High BAR values were associated with higher risk of mortality (OR: 4.63; 95% CI 2.11–10.15; p < 0.001). However, no statistically significant association was found between BAR values and the risk of severity (OR: 1.16; 95% CI 0.83–1.63; p = 0.38). High FAR and BAR values were associated with poor clinical outcomes.es_PE
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherMDPIes_PE
dc.relation.urlhttps://www.mdpi.com/2414-6366/7/8/150es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Academico - UPCes_PE
dc.subjectalbumines_PE
dc.subjectblood urea nitrogenes_PE
dc.subjectCOVID-19es_PE
dc.subjectfibrinogenes_PE
dc.subjectureaes_PE
dc.titleFibrinogen-to-Albumin Ratio and Blood Urea Nitrogen-to-Albumin Ratio in COVID-19 Patients: A Systematic Review and Meta-Analysises_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.eissn24146366
dc.identifier.journalTropical Medicine and Infectious Diseasees_PE
dc.description.peerreviewRevisión por pareses_PE
dc.identifier.eid2-s2.0-85136999431
dc.identifier.scopusidSCOPUS_ID:85136999431
dc.source.journaltitleTropical Medicine and Infectious Disease
dc.source.volume7
dc.source.issue8
refterms.dateFOA2022-09-08T23:40:38Z
dc.identifier.isni0000 0001 2196 144X


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