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dc.contributor.authorAcosta, J.
dc.contributor.authorFlores, P.
dc.contributor.authorAlarcón, M.
dc.contributor.authorGrande-Ortiz, M.
dc.contributor.authorMoreno-Exebio, L.
dc.contributor.authorPuyen, Z. M.
dc.date.accessioned2022-03-04T11:11:49Z
dc.date.available2022-03-04T11:11:49Z
dc.date.issued2022-01-01
dc.identifier.issn10273719
dc.identifier.doi10.5588/ijtld.21.0373
dc.identifier.urihttp://hdl.handle.net/10757/659237
dc.description.abstractBACKGROUND: Adherence to TB treatment and therefore treatment success could be improved using digital adherence technology. OBJECTIVE: To evaluate the effectiveness of a medication event reminder monitor system (MERM) on treatment success and treatment adherence in patients with drug-susceptible pulmonary TB in Perú. METHODS: This was an experimental, randomised, open-label, controlled study conducted among patients in the second phase of TB treatment. The intervention group received their medications through MERM with the support of a treatment monitor, whereas the control group used the usual strategy. Participants were followed until they completed the 54 doses of the second phase of treatment. RESULTS: The study included 53 patients in each group; four in the intervention group withdrew from the study. Treatment success was significantly more frequent in the MERM group (RR 1.15, 95% CI 1.02–1.30; P = 0.0322). There was no significant difference in the adherence outcomes; however, the percentage of patients who missed at least one dose and patients with more than 10% of total doses missed were lower in the intervention group. CONCLUSION: The use of MERM in the second phase of treatment showed a significant improvement in the treatment success rate in patients with drug-susceptible pulmonary TB.es_PE
dc.description.sponsorshipNational Institutes of Healthes_PE
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherInternational Union Against Tuberculosis and Lung Diseasees_PE
dc.relation.urlhttps://www.ingentaconnect.com/content/iuatld/ijtld/2022/00000026/00000001/art00009es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Academico - UPCes_PE
dc.subjectDigital adherence technologieses_PE
dc.subjectDispenser pillboxes_PE
dc.subjectTreatment adherencees_PE
dc.subjectTreatment successes_PE
dc.titleA randomised controlled trial to evaluate a medication monitoring system for TB treatmentes_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.eissn18157920
dc.identifier.journalInternational Journal of Tuberculosis and Lung Diseasees_PE
dc.description.peerreviewRevisión por pareses_PE
dc.identifier.eid2-s2.0-85123036570
dc.identifier.scopusidSCOPUS_ID:85123036570
dc.source.journaltitleInternational Journal of Tuberculosis and Lung Disease
dc.source.volume26
dc.source.issue1
dc.source.beginpage44
dc.source.endpage49
refterms.dateFOA2022-03-04T11:11:50Z
dc.identifier.isni0000 0001 2196 144X


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