Identification of coinfections by viral and bacterial pathogens in covid-19 hospitalized patients in peru: Molecular diagnosis and clinical characteristics
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Authors
Pérez-Lazo, GiancarloSilva-Caso, Wilmer
Del Valle-Mendoza, Juana
Morales-Moreno, Adriana
Ballena-López, José
Soto-Febres, Fernando
Martins-Luna, Johanna
Carrillo-Ng, Hugo
Del Valle, Luís J.
Kym, Sungmin
Aguilar-Luis, Miguel Angel
Peña-Tuesta, Issac
Tinco-Valdez, Carmen
Illescas, Luis Ricardo
Issue Date
2021-11-01
Metadata
Show full item recordPublisher
MDPIJournal
AntibioticsDOI
10.3390/antibiotics10111358Additional Links
https://www.mdpi.com/2079-6382/10/11/1358Abstract
The impact of respiratory coinfections in COVID-19 is still not well understood despite the growing evidence that consider coinfections greater than expected. A total of 295 patients older than 18 years of age, hospitalized with a confirmed diagnosis of moderate/severe pneumonia due to SARS-CoV-2 infection (according to definitions established by the Ministry of Health of Peru) were enrolled during the study period. A coinfection with one or more respiratory pathogens was detected in 154 (52.2%) patients at hospital admission. The most common coinfections were Mycoplasma pneumoniae (28.1%), Chlamydia pneumoniae (8.8%) and with both bacteria (11.5%); followed by Adenovirus (1.7%), Mycoplasma pneumoniae/Adenovirus (0.7%), Chlamydia pneumoniae/Adenovirus (0.7%), RSV-B/Chlamydia pneumoniae (0.3%) and Mycoplasma pneumoniae/Chlamydia pneumoniae/Adenovirus (0.3%). Expectoration was less frequent in coinfected individuals compared to non-coinfected (5.8% vs. 12.8%). Sepsis was more frequent among coinfected patients than non-coinfected individuals (33.1% vs. 20.6%) and 41% of the patients who received macrolides empirically were PCR-positive for Mycoplasma pneumoniae and Chlamydia pneumoniae.Type
info:eu-repo/semantics/articleRights
info:eu-repo/semantics/openAccessAttribution-NonCommercial-ShareAlike 4.0 International
Language
engEISSN
20796382Sponsors
National Research Foundation of Koreaae974a485f413a2113503eed53cd6c53
10.3390/antibiotics10111358
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- Creative Commons