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  • Biochemical and hemostatic description of a thrombin-like enzyme TLBro from Bothrops roedingeri snake venom

    Vilca-Quispe, Augusto; Alvarez-Risco, Aldo; Gomes Heleno, Mauricio Aurelio; Ponce-Fuentes, Emilio Alberto; Vera-Gonzales, Corina; Zegarra-Aragon, Herly Fredy Enrique; Aquino-Puma, Juan Luis; Talavera-Núñez, María Elena; Del-Aguila-Arcentales, Shyla; Yáñez, Jaime A.; Ponce-Soto, Luis Alberto (Frontiers Media SA, 2023-01-01)
    Objective: The current study’s objective is to characterize a new throm-bin-like enzyme called TLBro that was obtained from Bothrops roedingeris snake from a biochemical and hemostatic perspective. Methodology: One chromatographic step was used to purify it, producing the serine protease TLBro. Molecular mass was estimated by SDS-PAGE to be between reduced and unreduced by 35 kDa. Tryptic peptide sequencing using Swiss Prot provided the complete amino acid sequence. by conducting a search that is limited to Crotalinae snake serine proteases and displaying a high degree of amino acid sequence. Results: Ser (182) is inhibited by phenylmethylsulfonyl fluoride (PMSF), and TLBro demonstrated the presence of Asp (88) residues. It also deduced the positions of His (43) and Ser (182) in the set of three coordinated amino acids in serine proteases. It was discovered that this substrate had high specificity for BANA, Michaelis-Menten behavior with KM 0 point85 mM and Vmax 1 point89 nmoles -NA/L/min, and high stability between temperatures (15 to 70°C) and pHs (2 point0 to 10 point0). According to doses and incubation times, TLBro degraded fibrin preferentially on the B-chain; additionally, its activities were significantly diminished after preincubation with divalent ions (Zn2 and Cd2). When incubated with PMSF, a particular serine protease inhibitor, enzymatic activities and platelet aggregation were inhibited. Conclusion: The findings revealed distinct structural and functional differences between the serine proteases, adding to the information and assisting in the improvement of the structure-function relationship.
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  • Prevalence of post-traumatic stress disorder risk post-COVID-19 in 12 countries in Latin America: a cross-sectional survey

    Mejia, Christian R.; Serna-Alarcón, Víctor; Vilela-Estrada, Martín A.; Armada, Jose; Ubillus, Milward; Beraún-Barrantes, Jose; Álvarez-Risco, Aldo; Del-Aguila-Arcentales, Shyla; Davies, Neal M.; Yáñez, Jaime A. (Frontiers Media SA, 2023-01-01)
    Introduction: Latin America was the region most affected by COVID-19 in the second quarter of 2020, and consequently, the impact on mental health requires evaluation. The aim of this study was to assess the risk of post-traumatic stress disorder (PTSD) caused by bereavement due to COVID-19 in 12 countries in Latin America. Methods: The current study was an analytical cross-sectional study. Validated tests were applied for PTSD, depression, anxiety, and stress (DASS-21), questions about the respondent’s condition or their environment, and demographic questions, as well as the length of the mourning period of suffering. Results: The outcomes demonstrated that the PTSD risk increased for women (p < 0.001), when a friend or acquaintance had COVID-19 (p = 0.002), when a close relative died from COVID-19 (p = 0.010), having severe depression (p <0.001), severe anxiety (p <0.001), severe stress (p <0.001), residing in Chile (p <0.001), Paraguay (p <0.001), Bolivia (p <0.001), Costa Rica (p <0.001) or El Salvador (p = 0.005). On the other hand, there was less risk of PTSD at an older age (p <0.001) or if respondents had a sentimental partner (p = 0.025). In the case of severe PTSD, there was a greater gender risk for women (p <0.001), a close relative dying from COVID-19 (p = 0.017), having severe depression (p <0.001), severe anxiety (p <0.001), severe stress (p <0.001), residing in Chile (p <0.001), Paraguay (p <0.001), Bolivia (p <0.001) and Costa Rica (p = 0.002). It was also observed that there was less risk of severe PTSD at an older age demographic (p <0.001). Discussion: It can be concluded that the percentages of PTSD are high in its clinical presentation as severe, especially among Latin American women.
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  • Higher education student's attitude towards using gamification and its relation with achievement

    Celis, Magna Guerrero; Fajardo, Soraya Yrigoyen; Sambuceti, Giovanna Vassallo; Barros, Rossana (Institute of Electrical and Electronics Engineers Inc., 2023-01-01)
    The aim of this study was to determine the possible relation between higher education students' attitude towards the use of gamification with their academic performance. 'Gamification is using game-based mechanics, aesthetics and game thinking to engage people, motivate action, promote learning, and solve problems' [1, p. 10]. 280 first year university students taking a basic mathematics course participated in the study. Gamification activities were part of the course. Students were asked to answer a survey that measured their attitude towards the gamification activities and a survey that assessed their motivation. Students were also assessed on mathematical achievement. Correlations between the measures were carried out to find out if there is a relationship between their attitude toward these activities, their motivation and their performance. Results show that there was a significant relation between attitude towards gamification activities and student's motivation (r=.92, p<.01), but two correlations between attitude and motivation with their mathematical achievement were found non-significant (r=.04,p=.65;r=.02, p=.76). These results highlight the importance of using new activities like gamification to keep students motivated, but this has no relation with their performance. A future experimental study is needed to assess the impact of these activities on students learning.
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  • Oral Expression in Higher Level Students from the Virtual Modality

    Tippe-Marmolejo, Sindy; Zavala, Giomar Renzo Bazan; Giraldo, Susan Lizeth Soto (Institute of Electrical and Electronics Engineers Inc., 2022-01-01)
    The objective of this study was to determine the relationship between the virtual modality from a remote teaching context with oral expression in students of a private institution of higher education in Lima, a relationship supported based on the theory of connectivity. For this purpose, basic research was carried out, with a quantitative approach, correlational level and non-experimental design. The population consisted of 240 students and a sample of 118 students from Administration and Business careers. For the collection of data related to oral expression, a rubric was developed; while, for the virtual modality variable from a remote teaching context, an adapted survey was applied, whose reliability, through Cronbach's Alpha, was 0.949. On the other hand, these instruments were validated through expert judgment, who gave their agreement. Thus, from the analysis of the data collected and the application of the hypothesis test, it was shown that there is a positive relationship between the virtual modality from a remote teaching context and oral expression.
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  • Girls Wellbeing: Anxiety And Mathematical Achievement At The End Of Primary School

    Salinas, Gianela; Portocarrero, Tatiana; Barros, Rossana (Institute of Electrical and Electronics Engineers Inc., 2022-01-01)
    The aim was to determine whether there is a relationship between anxiety and mathematical performance in sixth grade primary school students, and if gender differences exist. Mathematics anxiety is a type of anxiety that affects this specific academic area or it is triggered by it. Studies have shown that students from the beginning of adolescence show mathematics anxiety and it increases as they progress through an academic environment. There is evidence to suggest that two important factors play a role in mathematics anxiety: the educational level and gender. There is consistent evidence that girls tend to be more affected by it than boys, but this has not been studied in primary school. 149 sixth grade students (mean age 140.5 months) from four schools in two Peruvian cities participated in two assessments, one that aimed to assess their level of mathematical anxiety and one that aimed to assessed their mathematical achievement. Results revealed that although there is no relation between mathematical anxiety and mathematical performance in sixth grade students, there are gender differences. Females (n=72) have an almost significant relationship (r=-.227, p=0.56). Presenting a lower mean in mathematics achievement compared to their male counterpart (x=14.05 and 15.71 respectively) and higher anxiety (x=49.92 and 42.64 respectively). This evidence has theoretical and practical implications in education, supporting girls' anxiety, as this could have a negative impact on their academic performance and wellbeing.
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  • Perceptions of higher education teachers about academic dishonesty in students within a virtual environment

    De Fatima Uceda, Sebastiana; Perez, Jose; Barros, Rossana; Flores, Mayllorid (Institute of Electrical and Electronics Engineers Inc., 2022-01-01)
    This study had two aims. The first aim was to identify the perceptions that higher education teachers of an education faculty, in a virtual environment, have about the factors that influence the decisions of the students to carry out dishonest academic behaviors. The second aim was to identify what measures teachers implement to prevent dishonest behaviors. Academic dishonesty is understood as the set of attitudes and actions that have the purpose of deceiving another person, and are carried out when one wants to present an academic work as one's own when in reality it is not in this way, violating the norms of the institution [1]. The present work is a qualitative research of an exploratory nature and a phenomenological approach. Semi-structured interviews were used with eight teachers. Data was analyzed: first, the concept of academic dishonesty, then the mechanism used by teachers and the institution to deal with these behaviors; finally, individual and contextual factors that may influence the student's decision to perform a dishonest behavior.
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  • Strategies to reduce academic stress in postgraduate students in the distance education modality in times of COVID-19

    De Los Angeles Sanchez-Trujillo, Maria; Egusquiza, Delia Felicita Saenz; Peralta, Melva Natalia Leon; Flores, Eduar Antonio Rodriguez (Institute of Electrical and Electronics Engineers Inc., 2022-01-01)
    The current context of a pandemic associated with a new remote educational modality has generated various effects on the world population. University students, and specifically postgraduate students, face various challenges to adapt to this new reality, which could generate certain levels of academic stress. This research of mixed nature sought, first, to determine the main frequencies of the dimensions of academic stress in 67 students of the master's degree in Education of a private university of Lima for which the Inventory of Academic Stress SISCO SV adapted to this context was applied. Secondly, it aimed to propose and evaluate strategies aimed at improving the psychological well-being of these students based on a focus group made to the students. In the initial findings, certain stressors perceived by the students were identified, such as the overload of tasks and works, the manner of evaluation of the teachers, and the perception about the limited time to do the works. In addition, among the most recurrent symptoms, are chronic fatigue, drowsiness or increased need for sleep, restlessness, and anxiety. From the application of strategies of an emotional and academic nature, there was an improvement in the perception declared by the students, which favored their psychological well-being.
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  • Structural Characterization of Factors for the Digital Training of Public Primary School Teachers: The Peruvian Case

    Del-Valle-Rojas, Ivette Anne; Callupe-Ricaldi, Angela Luz; Ruiz-Ruiz, Marcos Fernando (Latin American and Caribbean Consortium of Engineering Institutions, 2023-01-01)
    The aim of this study was to determine the key factors of the digital teacher training system in public primary schools, which aims to improve teachers' digital competence. Digital competence is defined as the creative, critical, and safe use of Information and Communication Technologies (ICT) [1]. Worldwide, several countries use within their digital training programs institutional frameworks such as the European Framework for the Digital Competence of Educators, the International Society for Technology in Education (ISTE) and/or UNESCO [2] [3]. In Peru, the Framework for Good Teaching Performance, a guiding document for public teachers, only encourages its use according to the purpose of the learning session. In 2020, the Closing Digital Divide strategy revealed that 81% of public teachers required training to integrate technologies into their pedagogical practice. This study used structural analysis to analyse key factors in teachers' training to improve their digital competence. Results showed that among the key factors of the training system were the differentiated support in the use of ICT, the courses based on the participants' profile, the blended learning model, the technological infrastructure within the institutions and the creation of digital competence within the Framework of Teaching Performance. The results provide support to provide guidance to create the required digital training for teachers. Future research should evaluate digital teacher training policies, as well as the role of the school leaders in the implementation of ICT.
    Acceso abierto
  • Formative Feedback in Blackboard Learn Environment for College Academic Literacy of Engineering Students

    Ramos-Neyra, Mónica F.; Felipa Andrade, Rossana F.; Ramírez-Rodríguez, Laritza T.; Tippe-Marmolejo, Sindy; Riega-Virú, Yasmina (Latin American and Caribbean Consortium of Engineering Institutions, 2023-01-01)
    The COVID-19 pandemic spread the virtual mode to the masses through various learning platforms. In higher education, the possibilities offered by these platforms were used to innovate evaluation in e-learning environments. Due to the formative needs of engineering students regarding academic writing, the objective of the research is to determine the impact of virtual formative feedback on the academic literacy of engineering students in a writing course with the support of the virtual learning environments. The study corresponds to a pre-experimental investigation in a sample made up of 39 students. The Wilcoxon signed rank test gave an overall value of -5.388b. Therefore, it demonstrates that formative feedback has a positive impact on the development of academic literacy in the Blackboard virtual environment.
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  • New Transformation Rules for the EduBPMN Method to Generate Graphical User Interfaces from BPMN

    Diaz, Eduardo; Panach, Jose Ignacio (Institute of Electrical and Electronics Engineers Inc., 2022-01-01)
    The EduBPMN method contains a set of transformation rules that allow the generation of Graphical User Interfaces (GUIs) from a BPMN model complemented by the UML class diagram. The article proposes new rules for the EduBPMN method based on BPMN primitives and operations of the UML classes. These rules can generate design alternatives for GUIs, each of which has been proposed to be represented by a stereotype. As a result of this work, four new rules and eight new stereotypes have been proposed to extend the EduBPMN method. For a better understanding of the contribution, it has been applied to an illustrative example of a project.
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  • Construcción de aprendizaje a través de organizadores gráficos en educación superior

    Rojas, Fiorella Valeria Villanueva; Caballero, Jesús Emilio Agustín Padilla; Alejos, Miguel Ángel Zubiaur; Zapata, Consuelo de María Orellana; Ticona, María Isabel Mamani (Associacao Iberica de Sistemas e Tecnologias de Informacao, 2022-01-01)
    In recent years, technology applied to education has advanced by leaps and bounds; Pressured by the Covid-19 pandemic, it has been necessary to move from face-to-face to virtual, which has required teachers to show the full potential of digital tools, such as visual organizers. The objective of the research was the interpretation of the utility of graphic organizers (GO) for the acquisition of learning in higher education students. The methodology used was qualitative, a type of basic research of hermeneutic design; Through interviews with teachers with expertise in GO, interviews were conducted with teachers with extensive experience in the use of GO, processing the information with AtlasTi. As a result, the relevance of using the GO in higher education teaching was obtained, while emerging categories were obtained that will allow the best interpretation of the study variable. It is concluded that the use of GO has a positive significance in the assimilation of new knowledge to achieve significant learning.
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  • Digital Gaps Influencing the Online Learning of Rural Students in Secondary Education: A Systematic Review

    Samane-Cutipa, Virginia A.; Quispe-Quispe, Ana M.; Talavera-Mendoza, Fabiola; Limaymanta, Cesar H. (International Journal of Information and Education Technology, 2022-07-01)
    —The digital gaps that were amplified due to the COVID-19 pandemic deepened more in vulnerable areas in different parts of the world. The present work aims to analyze the study of digital gaps that influence online learning of students from rural areas in secondary education, based on a systematic review of the literature. It was developed using the PRISMA methodology, the scientific information was retrieved from the Web of Science and ERIC databases in a period of three months. In the searches it was taken as inclusion criteria; open access, year of publication 2017-2021, English and Spanish language, rural secondary education level and exclusion; articles whose studies were carried out in higher education, in specific areas, related to research policies, evaluation, studies before 2017 and articles from systematic reviews. The results and findings emphasize that digital literacy levels are scarce and limited in terms of the skills developed by students and teachers to achieve digital competencies, in addition to restricted access due to technological, economic, and coverage gaps of families. The conclusions are aimed at strengthening urgent educational policies in addition to the integration of the school curriculum.
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    Palacios-Núñez, Madeleine; Deroncele-Acosta, Angel; Cruz, Félix Fernando Goñi (UNIVERSIDADE FEEVALE, 2022-07-01)
    The application of Online Collaborative Learning (ACL) in the classroom is a necessary challenge within the framework of digital literacy to generate relevant learning for life; therefore, it requires proper management. This work focuses on diagnosing the current state of the ACL and identifying its success factors. The applied methodology was a study with a mixed approach, applying the multiple case study method (design) by questionnaire and semi-structured interview to teachers and university students. The scientific contribution of this research is related to the revelation of new ACL-enhancing processes such as the development of critical-reflective thinking, assertive-empathic communication, self-managed responsible empowerment and the realization of proactive online entrepreneurship projects. It is concluded that the strengthening of the teaching digital competence, as well as the institutional role in the digital aspect, could contribute to enhance these success factors of the ACL and address the aforementioned needs.
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  • The Use of Augmented Reality to Strengthen Competence in Data Analysis and Problem Solving in Engineering Students at the Universidad del Valle de México

    Zamora-Antuñano, Marco Antonio; Barros-Baertl, Rossana; Tovar-Luna, Belzabeth; González-Gutiérrez, Carlos Alberto; Mendez-Lozano, Nestor Efren; Cruz-Perez, Miguel Ángel (MDPI, 2022-11-01)
    The objective of this research was to analyze the improvement in the data analysis and problem-solving competence of students of industrial and systems engineering (IIS) and mechatronics engineering (IMEC) through the use of this technology and its impact on the results of the undergraduate general examination (EGEL). A training course was held for teachers and students for the design of learning objects (LO), and a questionnaire on the use of AR and the improvement in learning was administered. AR is a technology that has begun to be introduced in different contexts and at different educational levels. The results obtained through the Wilcoxon test and the multiple correspondence analysis (MCA) showed that there were improvements in academic performance with the use of AR and an interest in this tool being used during the academic training process.
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  • Stress, Depression and/or Anxiety According to the Death by COVID-19 of a Family Member or Friend in Health Sciences Students in Latin America during the First Wave

    Mejia, Christian R.; Alvarez-Risco, Aldo; Mejía, Yaniré M.; Quispe, Susan C.; Del-Aguila-Arcentales, Shyla; Serna-Alarcón, Victor; Vilela-Estrada, Martín A.; Armada, Jose; Yáñez, Jaime A. (MDPI, 2022-12-01)
    The COVID-19 pandemic generated high mortality in various countries, which may have had an impact on the mental health of young people. The objective of the study was to evaluate whether the death of a family member or close friend due to COVID-19 generated a higher prevalence of depression, anxiety, or moderate/severe stress in university health sciences students in Latin America. This is an analytical cross-sectional study, with secondary data; depression, anxiety, and stress were measured with a validated survey. In addition, data were obtained on the deaths by COVID-19 of family members or close friends, illness and other socio-economic variables. Descriptive and analytical statistics were obtained. It was found that, of the 3304 students, 5.9% (190) had a close relative who had died, 11.2% (363) a distant relative, and 19.8% (641) a friend. According to the multivariate analysis, those students who had a close family member who had died had greater depression (RPa: 1.48; CI 95%: 1.20–1.84; value p < 0.001) and stress (RPa: 1.41; CI 95%: 1.11–1.79; p value = 0.005), in addition, those who had a friend who died had higher levels of anxiety (RPa: 1.20; 95% CI: 1.06–1.36; p value =0.005); also, the respondents who suffered from COVID-19 had greater depression (RPa: 1.49; CI 95%: 1.05–2.11; value p = 0.024) and stress (RPa: 1.55; CI 95%: 1.05–2.28, p-value = 0.028). An association was found between suffering from depression, anxiety, or stress, and having suffered the death of a family member or close friend from COVID-19. This finding is an important one for places of education to consider, suggesting a need to generate psychological support programs for students who have lost a loved one during the pandemic, since this could have academic and social repercussions. An association was found between the three mental illnesses studied and the death of a family member or close friend from COVID-19.
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  • Poverty, Household Structure and Consumption of Foods Away from Home in Peru in 2019: A Cross-Sectional Study

    Lozada-Urbano, Michelle; Huamán, Franklin; Xirinachs, Yanira; Rivera-Lozada, Oriana; Alvarez-Risco, Aldo; Yáñez, Jaime A. (MDPI, 2022-09-01)
    The aim of this study was to evaluate the probability of buying food away from home according to the type of household using the logit model, as well as the sociodemographic characteristics of the heads of household, and how much income expenditure represents. A cross-sectional study was carried out using the National Household Survey (ENAHO) 2019 database. After joining the database, the household type variables were created. To calculate the probability with the “logit” model of purchase, the variables—family size, income, types of household, and total expenditure—were selected as a measure of the purchasing power of the family. A statistically significant association (p < 0.05) was found between the probability of consumption and the variables: age of household members, predominance, nuclear without children–married, nuclear with children–cohabitant, nuclear with children–widowed, nuclear with children–separated, extended, compounded, poor not extreme, and not poor. The bulk of families was represented by nuclear families (61.97%). The highest expenditure in the CFAH was for families defined as composite with a yearly average of USD 1652.89 (equivalent to PEN 5520.67). Observing the expenditure on food consumed outside the home through the composition of households can allow a better approach to offer educational measures. This information can be helpful to developers of educational issues.
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  • Leadership and empowerment in businesswoman in Peru

    Tamara Tatiana, Pando Ezcurra; Luis Miguel, Cangalaya Sevillano; Zoran Evaristo, Herrera Mejía; Raúl Eduardo, Cabrejos Burga (Universidad del Zulia, 2022-01-01)
    Women’s ability to influence in the business sector is characterized by organization and the decisionmaking process. This study analyzes the leadership and empowerment of women entrepreneurs from Lima Norte in Peru. The research is carried out using the quantitative approach methodology; of non-experimental design, cross section, and probabilistic sampling, in which we worked with 70 businesswomen. The survey technique and the questionnaire instrument were used, validated through expert judgment, which obtained a high level of reliability. The results achieved allow us to affirm that empowerment influences the female leadership of businesswomen from Lima Norte in Peru and the individual capacity of each woman highlights autonomy, as well as self-sufficiency that account for empowerment in order to exert influence in the process. decision making It is concluded that the leadership exercised by women has a transformative vision, by providing the ability to influence business decision-making.
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  • Infancia y transgresión poética en la obra de Luis Hernández

    León Mango, Liz Fiorella (Pontificia Universidad Católica del Perú (PUCP), 2021-12-15)
    La infancia representó en el ideario del poeta moderno la avidez de conocimiento, el impulso lúdico-experimental y la conciencia material del arte. Estos rasgos pueden distinguirse en la obra de Luis Hernández, quien, revalorizando la infancia, planteó el ímpetu lúdico y la inocencia como claves de una producción artística original. Identificándose con la pureza de un niño, en un nivel temático, el poeta cuestionó la indolencia y el afán organizativo y alienante de todo autoritarismo. En cuanto al uso de los instrumentos técnico-formales, practicó con ellos tal y como un infante experimenta con sus objetos de juego, explotando sus posibilidades, despreocupado e irreverente. Dicho esto, nuestro objetivo es evidenciar cómo su reinterpretación de la infancia influyó en su cuestionamiento de los procesos de escritura, distribución y recepción de la literatura.
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  • Estrategias metodológicas en la educación ambiental. Estudio de caso de un docente de ciencias naturales de una institución educativa pública

    MARCELO VELIZ, BELMIRA YUNET (Pontificia Universidad Católica del Perú (PUCP), 2022-03)
    La investigación se enmarca en el enfoque ambiental que deben atender las instituciones educativas ante la urgencia que existe de actuar y asumir compromisos ambientales por amenazas ambientales locales, regionales y globales. Entonces, corresponde al docente aplicar estrategias metodológicas en la formación ambiental. La investigación nos brindará información de las acciones que viene realizando el docente desde su área de aprendizaje y poder identificar las estrategias aplicadas que permitan identificar y analizar un problema ambiental de su entorno para promover conciencia ambiental en los estudiantes.
    Acceso abierto
  • Themes of scientific production of the cuban journal of pharmacy indexed in scopus (1967-2020)

    Chung, Sun Ah; Olivera, Selma; Román, Brenda Rojas; Alanoca, Evelyn; Moscoso, Stephanie; Terceros, Bianca Limpias; Álvarez-Risco, Aldo; Yáñez, Jaime A. (Editorial Ciencias Medicas, 2021-01-01)
    Introduction: The Cuban Journal of Pharmacy celebrated this year its fifty-fourth anniversary, and during all these years it has successfully published more than 1110 works indexed in Scopus bibliographic database until 2020. Objective: Describe the scientific production from the thematic point of view of the Cuban Journal of Pharmacy indexed in Scopus. Methods: A qualitative study was carried out, based on the systematic review of scientific literature published by the Cuban Journal of Pharmacy, available in Scopus. Publications were grouped by thematic areas according to the authors' criteria, based on the keywords presented in the abstracts and the central theme of the article. The thematic areas defined were eight, with eight sub-themes. Conclusions: Since 1967, the Cuban Journal of Pharmacy has strived to promote the development of science and research in its home country, Cuba. However, because of the variety of its articles it is of great value to foreign researchers and students too. The studies presented have been characterized by the diversity of topics related to pharmacology, the use of Cuban medicinal plants for therapeutic purposes and the methodology for better drug’s production and laboratory procedures.
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