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dc.contributor.authorQuesada, Andrés E.*
dc.contributor.authorMedeiros, L. Jeffrey*
dc.contributor.authorClemens, Mark W.*
dc.contributor.authorFerrufino-Schmidt, Maria C.*
dc.contributor.authorPina-Oviedo, Sergio*
dc.contributor.authorMiranda, Roberto N.*
dc.date.accessioned2018-11-27T03:11:34Z
dc.date.available2018-11-27T03:11:34Z
dc.date.issued2018
dc.identifier.issn0893-3952
dc.identifier.issn1530-0285
dc.identifier.doi10.1038/s41379-018-0134-3
dc.identifier.urihttp://hdl.handle.net/10757/624650
dc.descriptionEl texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.es_PE
dc.description.abstractBreast implant-associated anaplastic large cell lymphoma is a newly recognized provisional entity in the 2017 revision of the World Health Organization Classification of Tumors of Hematopoietic and Lymphoid Tissues. It is an uncommon, slow growing T-cell lymphoma with morphology and immunophenotype similar to anaplastic lymphoma kinase-negative anaplastic large cell lymphoma. However, the presentation and treatment are unique. Breast implant-associated anaplastic large cell lymphoma often presents as a unilateral effusion confined to the capsule of a textured-surface breast implant, a median time of 9 years after the initial implants have been placed. Although it follows an indolent clinical course, breast implant-associated anaplastic large cell lymphoma has the potential to form a mass, to invade locally through the capsule into breast parenchyma or soft tissue and/or to spread to regional lymph nodes. In most cases, an explantation with a complete capsulectomy removing all disease, without chemotherapy is considered to be curative and confers an excellent event free and overall survival. Here we provide a comprehensive review of breast implant-associated anaplastic large cell lymphoma, including history, epidemiology, clinical features, imaging and pathology findings, pathologic handling, pathogenic mechanisms, model for progression, therapy and outcomes as well as an analysis of causality between breast implants and anaplastic large cell lymphoma.en_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.publisherNature Publishing Groupen_US
dc.relation.urlhttp://www.nature.com/articles/s41379-018-0134-3en_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Academico - UPCes_PE
dc.titleBreast implant-associated anaplastic large cell lymphoma: a reviewen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.identifier.journalModern Pathologyen_US
dc.description.peerreviewRevisión por pareses_PE
dc.contributor.email[email protected]es_PE
dc.source.journaltitleModern Pathology
refterms.dateFOA2018-11-27T03:16:17Z
dc.identifier.isni0000 0001 2196 144X


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