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dc.contributor.authorRuiz, Joaquim*
dc.contributor.authorUlloa, Gabriela M.*
dc.contributor.authorPons, Maria J.*
dc.contributor.authorVásquez-Achaya, Fernando*
dc.contributor.authordel Valle Mendoza, Juana*
dc.contributor.authorGomes, Cláudia*
dc.contributor.authordel Valle, Luis J.*
dc.date.accessioned2018-11-26T15:58:06Z
dc.date.available2018-11-26T15:58:06Z
dc.date.issued2018
dc.identifier.issn0002-9637
dc.identifier.issn1476-1645
dc.identifier.doi10.4269/ajtmh.18-0520
dc.identifier.urihttp://hdl.handle.net/10757/624642
dc.descriptionEl texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.es_PE
dc.description.abstractCarrion's disease is a neglected, vector-borne illness that affects Colombia, Ecuador, and especially Peru. The phlebotomine sand flies Lutzomyia verrucarum and Lutzomyia peruensis are the main illness vectors described, although other species may be implicated in endemic areas such as some northern Peruvian regions, in which Carrion's disease vector has not been established. The aim of this study was to evaluate the presence of Bartonella bacilliformis DNA in Lutzomyia maranonensis from Cajamarca, northern Peru. This sand fly has not been defined as a vector yet. Centers for Disease Control and Prevention light traps were used to collect adult phlebotomine sand flies from 2007 to 2008 in the Cajamarca department. Female specimens were identified using morphological keys and were grouped into pools of five sand flies, taking into account district and sampling site (intradomicile or peridomicile). DNA was extracted, and then conventional and real-time polymerase chain reaction (RT-PCR) were performed to detect B. bacilliformis and subsequently confirmed by sequencing. A total of 383 specimens of L. maranonensis species were analyzed. Two of 76 pools were positive for B. bacilliformis by sequencing; all positives pools were from Querocotillo district. In addition, Mesorhizobium spp. were identified in two pools of sand flies, which is an α-proteobacteria phylogenetically very close to B. bacilliformis. This study presents molecular evidence that suggests L. maranonensis is naturally infected by B. bacilliformis in the Cajamarca department. Further research should determine if L. maranonensis is a vector and could transmit B. bacilliformis.en_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.publisherAmerican Society of Tropical Medicine and Hygieneen_US
dc.relation.urlhttp://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0520en_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Academico - UPCes_PE
dc.titleMolecular Detection of Bartonella bacilliformis in Lutzomyia maranonensis in Cajamarca, Peru: A New Potential Vector of Carrion’s Disease in Peru?en_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.identifier.journalAmerican Journal of Tropical Medicine and Hygieneen_US
dc.description.peerreviewRevisión por pareses_PE
dc.contributor.emailgulloau92@gmail.comes_PE
dc.source.journaltitleThe American Journal of Tropical Medicine and Hygiene
dc.source.volume99
dc.source.issue5
dc.source.beginpage1229
dc.source.endpage1233
refterms.dateFOA2018-11-26T16:01:43Z
dc.identifier.isni0000 0001 2196 144X


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