Asociación entre el consumo de alcohol y resultados negativos en pacientes diagnosticados de tuberculosis pulmonar pansensible: Una revisión sistemática y meta-análisis
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AsesoresUgarte Gil, Cesar
Fecha de publicación2018-01-16
MetadatosMostrar el registro completo del ítem
CitationMeza Rodríguez, A., Antonio, J., Carpio, V., José, C., Ingeniería, F. DE, José Valderrama Carpio José Antonio Meza Rodríguez Asesor, C. Y., & Villarreal Castro, G. (2014). Asociación entre el consumo de alcohol y resultados negativos en pacientes diagnosticados de tuberculosis pulmonar pansensible: Una revisión sistemática y meta-análisis. Universidad Peruana de Ciencias Aplicadas (UPC). Retrieved from http://hdl.handle.net/10757/622842
ResumenBACKGROUND: Tuberculosis (TB) is a treatable and preventable infectious disease, however, it has high rates of morbidity and mortality, making it one of the most important diseases in the world. Different factors interfered with an adequate treatment, leading to loss to follow up and failure. Between these factors, there is alcohol consumption. OBJECTIVE: Evaluate the association between alcohol consumption and a negative treatment outcome of pulmonary TB. METHODS: A systematic research of the literature available was made in EMBASE, LILACS, PUBMED/MEDLINE and SCOPUS. We considered all the literature available till November 2017. Cohort and case-control studies that evaluated adult patients with diagnosis of pulmonary TB were included. RESULTS: A total of 19 studies were included in this study, of them 3 cohort studies found association between alcohol consumption and loss to follow up to TB treatment (Pooled RR: 2.26; 95% CI: 1.26-4.03). Other 13 papers evaluated association between alcoholism and loss to follow up, 7 of them were case and controls studies (Pooled OR: 2.86; 95% IC 2.01- 4.07) and the others 6 were cohorts (Pooled RR: 2.38; 95% CI: 1.65-3.43). We could not found association between alcoholism and failure. There was not significant variation in the pooled RR/OR valor post analysis based on sensibility. CONCLUSIONS: Alcohol consumption, especially alcoholism, increases the risk of loss to follow up during TB treatment. This study will encourage health personnel to detect opportunely patients that consume alcohol, which are a population at risk of developing a negative treatment outcome, and implement more comprehensive actions for better monitoring.
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