Epidemiología de la pre-eclampsia de Lima, Perú, 2000-2015 : Factores asociados y complicaciones asociadas en gestantes y neonatos de dos hospitales públicos
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AdvisorsSegura Paucar, Eddy Roberto
Sánchez Calderón, Sixto Enrique
MetadataShow full item record
Citation1. Coronel Acosta, Shadia ( 0000-0002-7092-6031 ) ; Monteverde Rodríguez MP( 0000-0003-3157-5117 ). Epidemiología de la pre-eclampsia de Lima, Perú, 2000-2015 : Factores asociados y complicaciones asociadas en gestantes y neonatos de dos hospitales públicos [Internet]. Universidad Peruana de Ciencias Aplicadas (UPC); 2018. Available from: http://hdl.handle.net/10757/622689
AbstractObjectives: To compare maternal and neonatal complications between pregnant women with and without PE, as well as factors associated. In addition, to describe sociodemographic characteristics of the pregnant women, characteristics of the birth and the newborn, as well as to identify the annual prevalence of PE within the period 2000-2015. Methods: Retrospective cohort study with data from the Sistema Informático Perinatal (SIP 2000) from the period 2000-2015 of two public hospitals in Peru. The factors and complications associated with pre-eclampsia were described and analyzed. Maternal and neonatal complications were analyzed individually and as combined results. We used the GLM Log-Binomial regression to estimate the crude and adjusted relative risk of the associated complications. Results: The total population was 147,809 and 5943 (4.02%) had PE. The proportion of primigravids and nulliparous, as the proportion of cesareans and newborns with low birth weight was higher in women with PE. The most prevalent maternal complication was abnormal labor progression among women without PE and placental abruption in women with PE. The most frequently neonatal complication was small for gestational age (without PE 5,98% vs PE 19,91%). There is a greater risk of presenting some maternal complication (RR = 1,92, 95% CI 1,75-2,12) and maternal death (RR = 8,01, 95% CI 3,07-20,93) when the pregnant woman has PE, adjusted for factors such as background, hospital and year. The risk is also higher for complications of the newborn (RR = 2,82, 95% CI 2,70-2,95) and neonatal death (RR = 2,63, 95% CI 2,25-3,05), with the same analytical considerations. Through the years (2000-2015) prevalence of PE varies between 2 and 7%. Conclusions: The majority of women are between 20 to 34 years. In the PE group there are more primigravidae and nulliparous, which are factors associated with pre-eclampsia. The prevalence of PE varies between 2-7% during the years, on average 4,02%. On maternal complications in women with PE the most frequent was placental abruption, and in the newborns small for gestational age. A mother with PE has 1,92 times more risk of presenting some complication in a adjusted analysis, and for the newborns 2,82 times more. On maternal death, pregnant women with PE have 8,01 more risk in the same analytical conditions, and for newborns a value of 2,63 times more risk.
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