Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
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Authors
Phan, Tung GiaDel Valle Mendoza, Juana Mercedes
Sadeghi, Mohammadreza
Altan, Eda
Deng, Xutao
Delwart, Eric
Issue Date
2017-10-17
Metadata
Show full item recordCitation
Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. 2017 Virus GenesPublisher
Springer International PublishingJournal
Virus genesDOI
10.1007/s11262-017-1514-3PubMed ID
29043660Additional Links
https://www.ncbi.nlm.nih.gov/pubmed/?term=29043660%5Buid%5DAbstract
Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample. The detection in human serum of nucleic acids from viral families not known to infect vertebrates may indicate contamination during sample collection and aliquoting or human infection by their presumed cellular host, here a fungus. The role, if any, of the non-vertebrate infecting viruses detected in serum in inducing fever is unknown.Type
info:eu-repo/semantics/articleRights
Archived with thanks to Virus genesinfo:eu-repo/semantics/openAccess
Language
engDescription
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.ISSN
1572-994Xae974a485f413a2113503eed53cd6c53
10.1007/s11262-017-1514-3
Scopus Count
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