Coronal microfiltration caused by temporary restorative materials is considered one of the causes of failure in endodontic treatments. As a result, in recent years it has been sought to create a temporary restoration material that is capable of avoiding this problem. Objective: compare in vitro coronal microfiltration of an "experimental cement" and four temporary restorative materials used in endodontics. Materials and methods: Class I cavities were made in 90 premolars, divided into 10 groups (n = 9) and evaluated in two time periods (1 and 2 weeks. The experimental cement was elaborated, later the coronal sealing of the dental pieces was carried out, with experimental Cement,F (VOCO), Eugenato (MOYCO), Ketac ™ Molar Easymix 3M (ESPE) and Coltosol®F were used for the preparation of the experimental. The specimens were immersed in Chinese ink (Pelikan) for 1 and 2 weeks. Microfiltration at the dentinal wall-temporal restoration interface was evaluated using a stereomicroscope (Leica Microsystems LAS EZ version 2.0.0). Results: We found statistically significant differences (p <0.05) when coronal microfiltration of the five temporary restoration materials were compared, according to the ink exposure time (1 and 2 weeks). In both weeks, the experimental cement presented less filtration than Coltosol® F and Ketac ™ Molar Easymix 3M (ESPE). On the other hand, when comparing the coronal microfiltration of the experimental cement with each of the temporary restoration materials, we found statistically significant differences for the experimental group - Ketac ™ Molar Easymix 3M (ESPE) in the first week (p <0.001) and in the second week (p = 0.003). Conclusion: Experimental Cement presented lower microfiltration than Coltosol® F and Ketac ™ Molar EasyMix 3M (ESPE). However, none of the materials were able to prevent microfiltration totally.