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  • Frecuencia y factores asociados a viremia intermitente en personas viviendo con VIH/SIDA en el programa de un hospital de Lima, Perú

    Benites Zapata, Vicente A.; Pinto Dongo, Claudia Estefany (Universidad Peruana de Ciencias Aplicadas (UPC), 2018-03-31)
    Objectives: To identify the factors associated with intermittent viremia in PLWHA who entered the HIV / AIDS program of the Edgardo Rebagliati Martins National Hospital between 2010 and 2014. Materials and methods: A secondary analysis of a database of PLWHA assisted the National Hospital Edgardo Rebagliati Martins; calculated considering that the base has 520 participants in TARGA, a frequency of intermittent viremia in patients on treatment with a protease inhibitor base of 48%. In this study it was not necessary to use an instrument, since it is based on a secondary basis. Results: When performing the statistical analysis of the variables, no association was found. The participants who had co-infection with tuberculosis were 46, representing 8.8%; and received prophylaxis with CMX 226 (43.5%) participants. The participants who presented an intermittent viremia were 37, representing an incidence of 7.12%. Conclusions: No factor associated with the variable intermittent viremia was found. The identification of associated factors would have been important to reduce the transmission of HIV and the development of resistance to TARGA.
  • Factores Asociados y Alteraciones del Neurodesarrollo más frecuentes en el Recién Nacido Prematuro, registrados en el servicio de Terapia Física de un hospital público de Perú entre enero del 2015 a diciembre del 2016

    Becerra Bravo, Giancarlo; Bravo Cucci, Sergio; Ingar Romero, Renzo (Universidad Peruana de Ciencias Aplicadas (UPC), 2017-09-26)
    Objective: To identify the associated factors and to describe the most frequent neurodevelopmental alterations in a population of premature babies in Lima. Methodology: Cross-sectional analytical study realized at the San Bartolome Hospital from January 2015 to December 2016; the data were extracted from the Clinical Histories of the Archives Service, the evaluations were done by the professionals in charge, according to the clinical practice guide. These data were age and perinatal history of the mother, gestational age, weight, APGAR score and gender of the newborn. The test we used were T Student, Chi-square, Fisher's Exact Test and the sum of wilcoxon ranges; for the Ratio of Prevalence Crude and Adjusted were based on the Generalized Linear Model of Poisson with Robust Variances. Results: 480 clinical histories were included; the gestational age was 33.97±2.43 weeks with a weight of 1.860±0.480grams. There was no statistically significant association with the diagnoses in Physical Therapy p=0.054; however, not all preterm babies were diagnosed. Conclusions: Maternal age influences on the age of birth p=0.030 and some perinatal antecedents of the mother such as previous abortion p=0.026 and pre-eclampsia p≤0.001 as associated factors for premature birth.
  • Influencia de los medios de comunicación y el riesgo de padecer trastornos de la conducta alimentaria en escolares mujeres en Lima, Perú - 2014

    Mayta-Tristan, Percy; Lazo Montoya, Yessenia; Quenaya Quenaya, Alejandra Patricia (Universidad Peruana de Ciencias Aplicadas (UPC), 2015-04-01)
    Objective: Evaluate association between the mass media influence and the eating disorders risk in female students from Lima, Peru, 2014. Methodology: We performed a cross-sectional study in three schools in La Victoria District, Lima, Peru. Risk of eating disorders was measure with the “Eating Attitudes Test (EAT 26)” and the mass media influence with the “Sociocultural Attitudes towards Appearance Questionnaire-3 (SATAQ-3)” its categorized with tertiles in the global score and their sub scales (information access, pressure, general and athletic internalization). We calculated adjusted prevalence ratios (aPR) for eating disorder risk. Results: 483 participants were included; the mean age was 14 ± 3 years old, 13.9% had risk of eating disorders according to EAT-26. The students who are more influenced by the mass media (upper tertile of SATAQ-3) had more probability to have a risk of TCA (aPR: 4.24; 95CI: 2.10-8.56), those who have greater access to information (aPR: 1.89; 95CI: 1.09-3.25), higher pressure (aPR: 4.97; 95CI: 2.31-10.69), those who presented higher general internalization (aPR: 5.00; 95CI: 2.39-10.43) and who showed higher degree of athletic internalization (aPR: 4.35; 95CI: 2.19-8.66). Conclusion: The greater influence of the mass media is associate with more probability of eating disorders risk in female students from Lima.
  • Asociación entre síndrome metabólico y enfermedad nodular tiroidea en el Hospital Nacional Edgardo Rebagliati Martins en el año 2014

    Piscoya, Alejandro; Cornejo Champin, Raisa Amelia; Silva Caso, Wilmer Gianfranco; Soria Montoya, Andrea (Universidad Peruana de Ciencias Aplicadas (UPC), 2015-02-02)
    Introduction: Few studies analyses the relation between metabolic syndrome and thyroid nodular disease, subject in which there is a knowledge gap. The object of this study is to determinate the association between metabolic syndrome and thyroid nodular disease in a hospital in Lima, Peru. Materials and methods: A longitudinal, prospective, analytic, observational, case - control study, was performed “Hospital Nacional Edgardo Rebagliati Martins” in Lima- Peru. A total of 182 patients were separated as cases in which at least find a thyroid nodule detected by ultrasonography greater than 3 mm ( n = 91) and controls as patients in whom the presence of the node with the characteristics described was excluded by the same technique (n=91). The level and strength of association was evaluated between the presence of metabolic syndrome and each of its components by itself with the presence of thyroid nodular was evaluated. Results: Bivariate analysis shows significant association between the presence of thyroid nodule and metabolic syndrome with an OR of 2.56 (IC:95% 1.41 to 4.66, p < 0.05). Low levels of HDL and impaired fasting glucose are significant associated with the presence of thyroid nodule, independent of the presence of metabolic syndrome, with an OR of 2.81 (IC:95% 1.54 to 5.12, p<0.05) and 2.05 (IC: 95% 1.10 to 3.78, p<0.05) respectively. The multivariate analysis maintained the association between thyroid nodule and metabolic syndrome with an OR of 2.96 (IC: 95% 1,47 to 5,95 , p<0.05); like was the low levels of HDL with an OR of 2.77 ( IC: 95% 1,44 to 5,3, p<0.05) and with impaired fasting glucose with an OR of 2,23 ( IC 95% 1,14 to 4,34, p<0,05).Conclusions: Metabolic syndrome increases de risk of having thyroid nodule disease. Low HDL levels and impaired fasting glucose were the factors with more association.
  • Patrones radiológicos pulmonares y recuento de linfocitos cd4+ en pacientes VIH positivos coinfectados con tuberculosis pulmonar en HNGAI diagnosticados durante los años 1994-2011

    Carreazo, Nilton Yhuri; Vega Villanueva, Karen Isabel; Cortez Bazán, Nathaly (Universidad Peruana de Ciencias Aplicadas (UPC), 2014-06-30)
    En la tuberculosis pulmonar (TBP), ciertos patrones radiológicos como el cavitario han sido considerados “patognomónicos” de esta enfermedad. Sin embargo, esto resulta controversial en pacientes VIH positivos coinfectados con TBP ya que diversos estudios encontraron que existen patrones asociados a niveles de linfocitos T CD4+ mayores y menores de 200 células/mm3. El estudio de corte transversal realizado en el Hospital Nacional Guillermo Almenara Irigoyen (HNGAI) de la ciudad de Lima, Perú, durante los años 1994 al 2011. Se trabajó con la base de datos virtual del Servicio de Infectología de los cuales solo 241 pacientes fueron elegibles. Se excluyeron 112 pacientes que no cumplieron con los criterios de inclusión. Los patrones radiológicos se determinaron a partir del informe radiológico de la historia clínica, el diagnóstico de VIH se determinó mediante los test de ELISA y Western Blot y el conteo de linfocitos T CD4+ a través de citometría de flujo. El análisis bivariado se realizó con el test exacto de Fisher. Se consideró un p significativo con un valor <0.05. La población estuvo conformada por 129 pacientes, de los cuales el 77,5% fueron hombres. Se halló una mediana de 37 años para la edad de diagnóstico de TBP (RI= 30,5- 44), mientras que para el conteo de linfocitos T CD4+ la mediana resultó ser 59 (RI= 22- 206). El 73,6% (n= 95) de los pacientes presentaban un conteo de linfocitos T CD4+ <200 células/mm3. El patrón intersticial fue el más frecuente (25,6%) de la muestra, seguido por el patrón normal (23,7%). Dentro de los hallazgos principales, el patrón que presentó mayor predominio de pacientes con CD4+ ≥200 células/mm3 fue el normal con un 35,14%. Mientras que el patrón que presentó mayor cantidad de pacientes con CD4+ <200 células/mm3 fue el patrón pleural con un 83.33% dentro de este grupo.

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