• Obesidad abdominal y ausentismo por causa médica en una empresa de la industria metalmecánica en Cali, Colombia.

      Agredo Zúñiga, Ricardo A.; García Ordoñez, Emily S.; Osorio, Carlos; Escudero, Natalia; López-Albán, Carlos A.; Ramírez-Vélez, Robinson (Instituto Nacional de Salud (INS), 2014-03-25)
      Con el objetivo de examinar la frecuencia de obesidad abdominal y el ausentismo laboral por causa médica, se realizó un estudio transversal en 185 varones pertenecientes a una industria metalmecánica. En ellos, además de datos sociodemográficos, se recogió datos antropométricos y se midió la circunferencia de cintura (CC) en centímetros como indicador de obesidad abdominal. Se encontró, además de una alta frecuencia de obesidad abdominal (28,7%), que los trabajadores con obesidad abdominal presentaron mayor frecuencia, mayor tiempo y mayores costos por las incapacidades médicas. Se concluye que la obesidad abdominal en esta muestra fue altamente frecuente; no obstante, al tratarse de un riesgo reversible, las empresas podrían beneficiarse, en términos de ausentismo laboral, de programas preventivo promocionales destinados a controlar este problema.
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    • Obesity-related insulin resistance in adolescents: a systematic review and meta-analysis of observational studies

      Thota, P.; Perez-Lopez, F. R.; Benítes-Zapata, Vicente A.; Pasupuleti, V.; Hernandez, Adrian V.; School of Medicine, Case Western Reserve University, Cleveland, OH, USA,; Department of Obstetrics and Gynecology, University of Zaragoza Faculty of Medicine and Lozano Blesa University Hospital, Domingo Miral s/n, Zaragoza, Spain,; Center for Public Health Research, Research Institute, Faculty of Medicine, University of San Martin de Porres, Lima, Peru,; School of Medicine, Case Western Reserve University, Cleveland, OH, USA,; School of Medicine, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru, and; adrianhernandezdiaz@gmail.com (Taylor and Francis Ltd, 2017-01-19)
      Insulin resistance is common among obese adolescents; however, the extent of this problem is not clear. We conducted a systematic review of PubMed-Medline, CINAHL, The Web of Science, EMBASE and Scopus for observational studies evaluating components defining insulin resistance (insulin, C-peptide and homeostatic model assessment-insulin resistance [HOMA-IR]) in obese adolescents (12–18 years) versus non-obese adolescents. Our systematic review and meta-analysis followed the PRISMA guidelines. Data were combined using a random-effects model and summary statistics were calculated using the mean differences (MDs). 31 studies were included (n = 8655). In 26 studies, fasting insulin levels were higher in obese adolescents when compared to non-obese adolescents (MD = 64.11 pmol/L, 95%CI 49.48–78.75, p < 0.00001). In three studies, fasting C-peptide levels were higher in obese adolescents when compared to non-obese adolescents (MD = 0.29 nmol/L, 95%CI 0.22–0.36, p < 0.00001). In 24 studies, HOMA-IR values were higher in obese adolescents when compared to non-obese adolescents (MD = 2.22, 95%CI 1.78–2.67, p < 0.00001). Heterogeneity of effects among studies was moderate to high. Subgroup analyses showed similar results to the main analyses. Circulating insulin and C-peptide levels and HOMA-IR values were significantly higher in obese adolescents compared to those non-obese.
    • Oferta y composición nutricional de ensaladas en patios de comida de centros comerciales de Lima Metropolitana, 2014

      Bustamante García, Marifé; Martinez Feliu, Montserrat; Servan, Karin; Mayta-Tristan, Percy (Instituto Nacional de Salud (INS), 2016-01-25)
      Objetivos. Evaluar la oferta y composición nutricional de las ensaladas ofrecidas como plato principal en los patios de comida de los centros comerciales de Lima, Perú. Materiales y métodos. Se revisó las cartas de comida de todas las franquicias presentes en los patios de comida de los once centro comerciales de Lima, luego se evaluó la composición nutricional de las ensaladas ofertadas como plato principal calculando su contenido calórico, proteico, carbohidratos, grasas, colesterol, fibra y sodio, y la adecuación de ingesta para una cena (30% de una dieta de 2000 kcal). Resultados. Las ensaladas como plato principal representaron el 4,7% de la oferta, solo 7/17 franquicias ofrecían al menos una ensalada. El costo promedio de las ensaladas fue superior a los otros platos ($5,3 vs 4,7; p<0,001). El contenido calórico promedio fue de 329 kcal y de 2,7 g de fibra; con relación a una cena, se encontró un alto porcentaje de adecuación proteica (172,9%), de colesterol (121,0%), y bajo para calorías (54,8%), carbohidratos (23,1%) y fibra (36,4%). Conclusiones. Las ensaladas que se ofertan en patios de centros comerciales de Lima son escasas y más costosas, presentan poco aporte de fibra y altos contenidos de colesterol. Se deben revisar estrategias para mejorar la accesibilidad de ensaladas de calidad en escenarios donde solo ofertan comidas rápidas.
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    • Older adults with disability in extreme poverty in Peru: How is their access to health care?

      Flores-Flores, Oscar; Bell, Ruth; Reynolds, Rodney; Bernabé-Ortiz, Antonio (Public Library of Science, 2018-12-01)
      Background Disability rates increase with age. In 2012, Peruvian older adults ( 65 years) represented 9% of the population. Additionally, older population reported disabilities at about 5 times the rate of Peruvians between 36 and 64 years old, and 30% of older population lived in poverty. Peruvian seniors living in extreme poverty experience disabilities and the extent of their access to healthcare is unknown. Objective This study assesses associations between disability and access to healthcare among Peruvians older individuals living in extreme poverty. Methods Secondary analysis of a national representative population based survey that utilizes information from Peru’s 2012 survey Health and Wellbeing in Older Adults (ESBAM), which includes older adults living in extreme poverty. We define disability in terms of the Activities of Daily Living (ADL disability) framework. Healthcare access was assessed as having any of Peru’s available health insurance schemes combined with preventive health services (vision assessment, influenza vaccination, blood pressure assessment, diabetes screening, and cholesterol assessment). Poisson robust regression models were used to evaluate the associations among relevant variables. Prevalence Ratios and 95% confidence intervals (95%CI) were reported. Results Data from 3869 individuals (65 to 80 years old), of whom 1760 (45.5%) were females, were analyzed. The prevalence of ADL disability was 17.3% (95%CI: 16.0%-18.4%). In addition, more than 60% had never received any of the preventive measures evaluated, except for the blood pressure assessment. In the adjusted model, people with ADL disability had 63% less probability of having extensive insurance, compared to those without disability (p<0.05). Conclusions This study shows that this Peruvian older population living in extreme poverty has limited access to healthcare services. Although there was no consistent association between ADL disability and the healthcare access, there is an urgent need to reduce the inequitable access to healthcare of this poor Peruvian older population.
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    • Olga and olgim stage distribution according to age and helicobacter pylori status in a public hospital in Lima, Peru

      Ronquillo, Andrea Carlin; León, Alex Ventura; Ríos, Jorge L.Espinoza; Paredes, Eduar A.Bravo; Hinojosa, Paúl Gómez; Solis, Shirley Alva; Valdivia, José L.Pinto; Silva-Caso, Wilmer (Sociedad Argentina de Gastroenterologia, 2021-01-01)
      Introduction. The operative link for gastritis assessment (OLGA) and the operative link on gastric intestinal meta-plasia assessment (OLGIM) staging systems have been sug-gested to provide risk of assessment for gastric cancer. Objec-tive. To evaluate the distribution of OLGA and OLGIM staging by age and Helicobacter pylori status. Material and methods. We studied 197 subjects undergoing elective upper gastrointestinal endoscopy. The presence of the H. pylori and histological changes were evaluated using the updated Sydney system. Stages III and IV of OLGA/OLGIM were considered high risk stages. Results. The H. pylori rate was 56.85% (112/197). High-risk OLGA/OLGIM cases were rare: 7/112 (6.5%) cases of OLGA in the H. pylori positive group and 6/85 (7%) in the H. pylori negative group; 5 (4.4%) cases of OLGIM in the H. pylori positive and 6 (7%) in the H. pylori negative. The proportion of advanced stages of OLGA and OLGIM increased with age (p < 0.001). High-risk OLGA was not found before age 40 regardless of the presence of H. pylori, but increased to 16.2%, 10.3%, 17.3% and 40.8% in subjects in the fourth, fifth, sixth and seventh decade of life respectively. The OLGIM high risk showed a similar trend: 0% before 40 years and up to 22.6% in people of 70 years. Conclusions. High-risk OLGA/OLGIM cases are infrequent before age 40 and increase significantly with age. No relation was found with the presence of the H. pylori. According to these protocols, only a fifth of the patients would strictly require endoscopic control.
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    • Optimizing harvesting for facial lipografting with a new photochemical stimulation concept: One STEP technique™

      Centurión, Patricio; Gamarra, Ronald; Caballero, Gonzalo; Kaufmann, Paul; Delgado, Pia (Springer Science and Business Media Deutschland GmbH, 2020-12-01)
      Background: Facial fat grafting for rejuvenation is one of the most popular facial aesthetic procedures in plastic surgery. It is always challenging and since there are a lot of techniques for adipose tissue (AT) harvesting, there are no standard procedures that guarantee natural and long-lasting results. We developed the selective tissue engineering photo stimulation technique (One STEP™) in which we used a novel infrared 1210-nm wavelength laser diode for fat preserved harvesting and direct fat injection that we named PicoGraft™, with no fat manipulation. Methods: This is a retrospective descriptive study in which we included all senior author’s patients that got facial fat grafting using the One STEP™ technique. We compared the AT aspirated, after laser emission (STEP-PicoGraft) and the standard assisted liposuction samples (SAL) in cultures. We study the mitochondrial activity of the ASC between STEP and SAL in fresh samples and after 24 h. The evaluation of the results included subjective changes regarding wrinkles, grooves, palpebral bags, hyperchromic spots, and fat hypotrophy of our patients. Results: Between July 2013 and May 2018, a total of 245 patients underwent facial fat grafting using this novel technique. We observed adipocytes preserved after STEP harvesting comparing morphologic changes in SAL samples with a high concentration of inflammatory particles in cultures. ASC mitochondrial activity shows an important difference of more than 7 times in STEP samples in fresh analysis that increase 12 times in 24 h. The subjective results show a good improvement in the periorbital area. The changes on the skin and subcutaneous tissue are seen from the second month and continue to improve up to 12 months. Conclusions: Facial fat grafting using the PicoGraft™ obtained by One STEP™ technique gives excellent volumetric and regenerative results in a single treatment without volumetric hypercorrection, and it is a good alternative for facial rejuvenation. The fat graft obtained with this novel technique is homogenous, without lumps, and has high concentration of viable stimulated ADSC and a high number of viable adipocytes. Level of evidence: Level III, therapeutic study.
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    • Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: A systematic review and meta-analysis of randomized controlled trials

      White, C. Michael; Pasupuleti, Vinay; Roman, Yuani M.; Li, Yangzhou; Hernandez, Adrian V. (Academic Press, 2019-08-01)
      Turmeric extract or active component curcumin may have anti-inflammatory effects in people with chronic inflammatory diseases. The effect of turmeric or curcumin on a wide range of inflammatory markers has not been evaluated in a systematic review. We performed a systematic review of randomized controlled trials (RCTs)evaluating the effects of oral turmeric or curcumin on inflammatory markers (CRP, hsCRP, IL-1, IL-6, TNF)in patients with a wide range of chronic inflammatory diseases. Pubmed, EMBASE, Scopus, the Web of Science, and the Cochrane library were evaluated until June 2018. Random effects meta-analyses with inverse variance methods and stratified by turmeric or curcumin were performed. Effects were expressed as mean differences (MD)and their 95% confidence intervals (CI). Risk of bias of RCTs was evaluated with the Cochrane tool. Nineteen RCTs were identified; included patients had rheumatic diseases, advanced chronic kidney disease with hemodialysis, metabolic syndrome, and cardiovascular diseases. Turmeric was the intervention in 5 RCTs (n = 356)and curcumin/curcuminoids in 14 RCTs (n = 988). Follow up times ranged between 4 and 16 weeks. One RCT had high risk of bias. In comparison to controls, turmeric or curcumin did not significantly decrease levels of CRP (MD -2.71 mg/L, 95%CI -5.73 to 0.31, p = 0.08, 5 studies), hsCRP (MD -1.44 mg/L, 95%CI -2.94 to 0.06, p = 0.06, 6 studies), IL-1 beta (MD -4.25 pg/mL, 95%CI -13.32 to 4.82, p = 0.36, 2 studies), IL-6 (MD -0.71 pg/mL, 95%CI -1.68 to 0.25, p = 0.15), and TNF alpha (MD -1.23 pg/mL, 95%CI -3.01 to 0.55, p = 0.18, 7 studies). There were no differences between turmeric and curcumin interventions. High heterogeneity of effects was observed for all markers across studies, except hsCRP. Other inflammatory markers such as IL-1 alpha, TNF beta, IL-17, and IL-22 had scarce data. Turmeric or curcumin did not decrease several inflammatory markers in patients with chronic inflammatory diseases.
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    • Orbital presentation of Rosai-Dorfman disease

      Yataco-Vicente, J.A.; Araujo-Castillo, R.V.; López Fuentes, M.H.; javieryataco22@gmail.com (Elsevier Ltd, 2018-10)
      Objective: To report a case of orbital mass and proptosis, diagnosed as Rosai-Dorfman disease (RDD). Methods: Clinical case report based on the review of clinical charts, radiological images, and histopathology. Results: A 42-year-old male with orbital mass and proptosis of the right eye. A surgical biopsy was performed, and the diagnosis of RDD was established using microscopy and immunohistochemistry. Definitive management included open tumour cytoreduction, with good response. Discussion: The RDD is a rare, benign, proliferative condition of unknown origin. It rarely affects the cranial cavities, with the orbital presentation being very unusual. Diagnostic confirmation is essential for the best surgical management.
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    • Oropouche infection a neglected arbovirus in patients with acute febrile illness from the Peruvian coast

      Martins-Luna, J. (BioMed Central Ltd., 2020-02-10)
      Objective: To evaluate the frequency of infection caused by the Oropouche virus (OROV) in 496 patients with acute febrile disease (AFI), whose samples were obtained for the analysis of endemic arboviruses in a previous investigation carried out in 2016. Results: OROV was detected in 26.4% (131/496) of serum samples from patients with AFI. Co-infections with Dengue virus (7.3%), Zika virus (1.8%) and Chikungunya (0.2%) were observed. The most common clinical symptoms reported among the patients with OROV infections were headache 85.5% (112/131), myalgia 80.9% (106/131), arthralgia 72.5% (95/131) and loss of appetite 67.9% (89/131). Headache and myalgia were predominant in all age groups. Both OROV infections and co-infections were more frequent in May, June and July corresponding to the dry season of the region.
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    • La ortorexia: Un nuevo reto para los profesionales de la salud

      Cavero, Vanessa; Lodwig, Cynthia; Lulli, Gabriela; Tejada, Romina (Sociedad Latinoamericana de Nutrición, 2015-09)
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    • Osteoarthritis in Latin America: Study of Demographic and Clinical Characteristics in 3040 Patients.

      Reginato, Anthony M; Riera, Humberto; Vera, Mariflor; Torres, Adrian R; Espinosa, Rolando; Esquivel, Jorge A; Felipe, Oscar Jair; Blas, Jorge Roman; Rillo, Oscar; Papasidero, Silvia; Souto, Renee; Rossi, Cesar; Molina, José F; Ballesteros, Francisco; Radrigan, Francisco; Guibert, Marlene; Chico, Araceli; Gil, María L; Camacho, Walter; Urioste, Lorena; Garcia, Abraham K; Iraheta, Isa; Gutierrez, Carmen E; Duarte, Margarita; Castañeda, Oswaldo; Coimbra, Ibsen; Muñoz Louis, Roberto; Reveille, John; Quintero, Maritza (Wolters Kluwer Health, Inc., 2015-12)
      BACKGROUND: Latin America is a heterogeneous region made up of different populations, cultures, latitudes, altitudes, and immigrants from different areas and ethnic groups. OBJECTIVE: The purpose of this study is to describe the clinical and demographic profile of patients with osteoarthritis (OA) evaluated by a selected group of rheumatologists in 13 Latin American countries. METHODS: A descriptive, observational, cross-sectional study was conducted in 13 Latin American countries of patients with symptomatic OA. Data were collected over a 3-month period using an ad hoc questionnaire to evaluate the clinical and demographic features of OA seen by rheumatologists. RESULTS: Among the 3040 patients, their average age was 62.5 years, and female-to-male ratio was 4.8:1. Patients with body mass index of greater than 30 kg/m or obesity was found in 38.2%. Approximately 88% had primary OA. Joints with OA were as follows: knee 31.2%, hand 9.5%, hand and knee 22.9%, proximal and distal interphalangeal joints (erosive OA) 6.5%, axial 6.6%, and hip 1.3%. Approximately 88.5% had radiographic severity of grade 2 or 3 on Kellgren-Lawrence scale (0-4). Nonsteroidal anti-inflammatory drugs were the predominant OA treatment included in combinations with glucosamine sulfate/chondroitin and viscosupplementation. Associated comorbidities included hypertension (39%), obesity (36.3%), diabetes mellitus (12%), and without comorbidity (12.7%). CONCLUSIONS: This is 1 of the largest population studies that evaluated the characteristics of OA in 3040 patients evaluated by rheumatologists in 13 Latin American countries. This study provides important data for each Latin American country to develop new health care planning in management of OA.
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    • Osteomielitis por Shewanella putrefaciens: reporte de caso y revisión de literatura

      Guinetti-Ortiz, Katia; Bocanegra-Jesús, Alejandra; Gómez de la Torre-Del Carpio, Andrea; katia.guinetti@gmail.com (Medwave, 2016-11-29)
      Shewanella putrefaciens is a Gram-negative bacillus and marine pathogen that rarely causes disease in humans. We report a case of osteomyelitis by this organism in a 48-year-old male patient, who presented with pain and erythema of the right foot that was initially diagnosed as cellulitis and did not revert despite treatment. He was transferred to Lima where osteomyelitis was diagnosed and started on empirical treatment with partial regression. A biopsy and culture of the compromised area found S. putrefaciens. The infection was treated according to the antibiotic sensitivity profile of the pathogen. S. putrefaciens infection represents a rare opportunistic infection of devitalized or exposed areas of the body. It is associated with residence in coastal areas and commonly affects the skin and soft tissues. Exceptional cases of osteomyelitis have been reported, but this is the first that involves the metatarsal bones. Shewanella putrefaciens es un bacilo Gram negativo, patógeno marino que rara vez ocasiona enfermedad en humanos. Se presenta un caso de osteomielitis por este microorganismo en un paciente varón de 48 años, procedente de Chimbote. Presentó dolor y eritema en el pie derecho, inicialmente diagnosticado como celulitis, pero que no revirtió pese al tratamiento. Fue transferido a Lima donde se diagnosticó osteomielitis e inició tratamiento empírico con escasa mejoría. Por ello, se realizó una biopsia y cultivo de la zona comprometida, el metatarso, en el cual se aisló Shewanella putrefaciens. Se trató de acuerdo al perfil de sensibilidad. La infección por Shewanella putrefaciens representa una rara infección oportunista, que se localiza en áreas desvitalizadas o expuestas del cuerpo. Se asocia a vivir en zonas costeras, afectando comúnmente piel y tejidos blandos. Se han reportado casos excepcionales de osteomielitis. Este es el primero que involucra metatarso.
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    • Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010

      Oré,Marianela; Sáenz, Eliana; Cabrera, Rufino; Sanchez, Juan F.; De Los Santos, Maxy; Lucas, Carmen M.; Núñez, Jorge; Edgel, Kimberly A.; Sopan, Justino; Fernández, Jorge; Carnero, G, Andres M.; Baldeviano, Christian; Arrasco, Juan C.; Graf, Paul C. F.; Lescano, Andres G. (American Society of Tropical Medicine and Hygiene, 2015-06-20)
      Military personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the incubation period was 2–36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 = 97%) and L. (V.) guyanensis (2/61 = 3%). Being male (risk ratio [RR] = 4.01; P = 0.034), not wearing long-sleeve clothes (RR = 1.71; P = 0.005), and sleeping in open rooms (RR = 1.80; P = 0.009) were associated with CL. Sodium stibogluconate therapy had a 41% cure rate, less than previously reported in Peru (70%; P < 0.001). After emphasizing pre-deployment education and other basic prevention measures, trainees in the following year had lower incidence (1/278 = 0.4%; P < 0.001). Basic prevention can reduce CL risk in deployed militaries.
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    • Outcomes of patients with severe tricuspid regurgitation and congestive heart failure

      Kadri, Amer N.; Menon, Vivek; Sammour, Yasser M.; Gajulapalli, Rama D.; Meenakshisundaram, Chandramohan; Nusairat, Leen; Mohananey, DIvyanshu; Hernandez, Adrian V.; Navia, Jose; Krishnaswamy, Amar; Griffin, Brian; Rodriguez, Leonardo; Harb, Serge C.; Kapadia, Samir (BMJ Publishing Group, 2019-12-01)
      Objectives A substantial number of patients with severe tricuspid regurgitation (TR) and congestive heart failure (CHF) are medically managed without undergoing corrective surgery. We sought to assess the characteristics and outcomes of CHF patients who underwent tricuspid valve surgery (TVS), compared with those who did not. Methods Retrospective observational study involving 2556 consecutive patients with severe TR from the Cleveland Clinic Echocardiographic Database. Cardiac transplant patients or those without CHF were excluded. Survival difference between patients who were medically managed versus those who underwent TVS was compared using Kaplan-Meier survival curves. Multivariate analysis was performed to identify variables associated with poor outcomes. Results Among a total of 534 patients with severe TR and CHF, only 55 (10.3%) patients underwent TVS. Among the non-surgical patients (n=479), 30% (n=143) had an identifiable indication for TVS. At 38 months, patients who underwent TVS had better survival than those who were medically managed (62% vs 35%; p<0.001). On multivariate analysis, advancing age (HR: 1.23; 95% CI 1.12 to 1.35 per 10-year increase in age), moderate (HR: 1.39; 95% CI 1.01 to 1.90) and severe (HR: 2; 95% CI 1.40 to 2.80) right ventricular dysfunction were associated with higher mortality. TVS was associated with lower mortality (HR: 0.44; 95% CI 0.27 to 0.71). Conclusion Although corrective TVS is associated with better outcomes in patients with severe TR and CHF, a substantial number of them continue to be medically managed. However, since the reasons for patients not being referred to surgery could not be ascertained, further randomised studies are needed to validate our findings before clinicians can consider surgical referral for these patients.
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    • Over 675,000 lay people trained in cardiopulmonary resuscitation worldwide - The "World Restart a Heart (WRAH)" initiative 2018.

      Böttiger, B W; Lockey, A; Aickin, R; Bertaut, T; Castren, M; de Caen, A; Censullo, E; Escalante, R; Gent, L; Georgiou, M; Kern, K B; Khan, A M S; Lim, S H; Nadkarni, V; Nation, K; Neumar, R W; Nolan, J P; Rao, S S C C; Stanton, D; Toporas, C; Wang, T-L; Wong, G; Perkins, G D (Elsevier Ireland Ltd, 2019-05-01)
      Cartas al editor
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    • Paediatric snakebite envenoming: the world's most neglected 'Neglected Tropical Disease'?

      Pach, Sophie; Le Geyt, Jacqueline; Gutiérrez, José María; Williams, David; Maduwage, Kalana Prasad; Habib, Abdulrazaq Garba; Gustin, Rafael; Avila-Agüero, María Luisa; Ya, Kyaw Thu; Halbert, Jay (NLM (Medline), 2020-12-01)
      Snakebite disproportionally affects children living in impoverished rural communities. The WHO has recently reinstated snakebites on its list of Neglected Tropical Diseases and launched a comprehensive Strategy for the Prevention and Control of Snakebite Envenoming. In the first of a two paper series, we describe the epidemiology, socioeconomic impact and key prevention strategies. We also explore current challenges and priorities including the production and distribution of safe and effective antivenom.
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    • Pancreatitis aguda debido a intususcepción gastroduodenal

      Salazar Alarcón, Jorge Luis; Arones Collantes, Ricardo Alfredo; León Estrella, Miguel Ángel; Peña Peña, Carlos Saúl; jorgesalazar635@gmail.com (Elsevier España S.L., 2016-10)
      Introducción: Los pólipos gástricos adenomatosos son poco frecuentes y generalmente se encuentran en el examen endoscópico de rutina. La intususcepción gastroduodenal es una com- plicación poco frecuente de los pólipos gástricos y ha sido raramente descrita como una causa de pancreatitis aguda. Caso clínico: Presentamos el caso de un varón de 68 anos ̃ el cual ingresa de urgencia con dolor abdominal, náuseas y vómitos catalogados en un inicio como pancreatitis aguda de etiología biliar; incidentalmente se descubre un pólipo gástrico pediculado intususceptado a duodeno como causa de la pancreatitis aguda. Se realizó tratamiento endoscópico de urgencia y trata- miento definitivo con cirugía abierta.
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    • Pancreatitis por citomegalovirus en inmunocomprometidos. Reporte de casos

      Salazar Huayna, Lourdes; Vélez Segovia, Eduardo; Ruelas Figueroa, José; Mendo Urbina, Fernando; Montiel-Gonzales, Marco (Asociación Colombiana de Gastroenterología, 2014-07-14)
      We report two cases of pancreatitis secondary to cytomegalovirus infections which were tested by reverse transcription polymerase chain reaction (RT-PCR) in patients with human immunodefi ciency virus (HIV). Other causes were ruled out by laboratory fi ndings. Both patients were treated with ganciclovir and improved clinically and as indicated by laboratory fi ndings. This condition should not be ignored in HIV-positive patients in spite of the absence of the clinical characteristics of acute pancreatitis.
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    • Pancreatitis por hipercalcemia secundaria a un adenoma de paratiroides y la presencia de un carcinoma papilar tiroides asociado

      Robles Cuadros, Juan Martín; Lastarria Bamberger, Carlos; Murillo Pérez, Diego; Rivas Ceballos, Jesús; Piscoya, Alejandro (2015-07-31)
      La pancreatitis aguda por hipercalcemia secundaria a hiperparatiroidismo primario es una etiología infrecuente. Presentamos una paciente mujer de 77 años que presentó dolor abdominal en hemiabdomen superior y vómitos; colecistectomizada, no bebe alcohol ni presenta dislipidemia. Los estudios de laboratorio mostraron, amilasa de 394 U/L y lipasa de 906 U/L, calcio sérico 17,93 mg/dL y el PTHi 441 pg/ml. En la TEM de cuello, se observó bocio multinodular (nódulos de 9 y 7 mm) en el lóbulo izquierdo de tiroides y un nódulo en paratiroides. La paciente fue sometida a una paratiroidectomía superior derecha y una hemitiroidectomía del mismo lado. Después de la cirugía, los niveles de Ca sérico y PTHi disminuyeron. Asimismo, como hallazgo en la biopsia, se encontró carcinoma papilar variante folicular de tiroides. Este reporte explica las posibles teorías de asociación entre adenoma paratiroideo y pancreatitis por hipercalcemia y describe además la asociación con carcinoma papilar variante folicular de tiroides, no antes descrito.
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    • Passive smoking could still represent a risk factor in Mexican children with asthma

      Pinedo Pichilingue, Aranza; Quijano Ono, Javier (Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI), 2014-07-03)
      We have read with interest the article by Bedolla et al. [1] and we believe the lack of association between passive smoking and asthma might be a consequence of the way the variable was measured. They defined passive smoking as follows: “smoking was considered as passive when one or more cigarettes were consumed by one or by both parents in the presence of the children”. We would like to highlight some factors that could have been taken into count when defining this variable: time of smoking, frequency and number of cigarettes.
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