• Encephalitis with convulsive status in an immunocompetent pediatric patient caused by Bartonella henselae

      Polar, Rosario Cerpa; Orellana, Gabriela; Caso, Wilmer Silva; Carbonel, José Sánchez; Santisteban, Javier; Del Valle Mendoza, Juana Mercedes; Santisteban, Javier (Elsevier B.V., 2016-03)
      Cat scratch's disease caused by Bartonella henselae, is known to be a self-limited benign process in immunocompetent children. The association with neurologic manifestations is very uncommon especially in patient with no immunologic defects and in cases without specific treatment. A 7 years old male patient, without any immunocompromised defect, presented an atypic presentation of the cat scratch disease. The patient came to the hospital in two opportunities in a status epilepticus, in both cases the diagnosis was encephalitis by Bartonella henselae and the evolution with treatment was monitored with PCR (polymerase chain reaction) in cerebrospinal fluid and blood, as well as IFI (IgM, IgG) serology (indirect immunofluorescence). The patient had a favorable clinical and laboratory evolution for 6 months showing no recurrence of the disease.
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    • Seronegative disseminated Bartonella spp. infection in an immunocompromised patient

      Weilg,Claudia; Del Aguila ,Olguita; Mazulis,Fernando; Caso Wilmer,Silvia; Alva Urcia, Carlos Alberto; Cerpa Polar,Rosario; Mattos Villena ,Erick; Del Valle Mendoza ,Juana (Elsevier B.V., 2016-11)
      An 11 year old, hispanic girl with a history of B-cell acute lymphoblastic leukemia was admitted to the hospital for symptoms compatible with Bartonella henselae infection. The first molecularly diagnosed case of disseminated Bartonella henselae infection was reported in an immunocompromised patient in Lima, Peru. The analysis was confirmed by Polymerase Chain Reaction and automated sequencing of a liver biopsy sample, even though the serologic tests were negative. In conclusion, Bartonella spp. infection should have a particular diagnostic consideration in immunocompromised patients with fever of unknown origin and further investigation regarding the patient's past exposures with cats should also be elicited.
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