• Antibacterial activity of five Peruvian medicinal plants against Pseudomonas aeruginosa

      Ulloa Urizar, Gabriela; Aguilar Luis, Miguel Angel; De Lama Odría, María del Carmen; Camarena Lizarzaburu, José; Del Valle Mendoza, Juana (Elsevier B.V., 2015-09-07)
      Objective: To evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) in vitro to the ethanolic extracts obtained from five different Peruvian medicinal plants. Methods: The plants were chopped and soaked in absolute ethanol (1:2, w/v). The antibacterial activity of compounds against P. aeruginosa was evaluated using the cupplate agar diffusion method. Results: The extracts from Maytenus macrocarpa (“Chuchuhuasi”), Dracontium loretense Krause (“Jergon Sacha”), Tabebuia impetiginosa (“Tahuari”), Eucalyptus camaldulensis Dehn (eucalyptus), Uncaria tomentosa (“Uña de gato”) exhibited favorable antibacterial activity against P. aeruginosa. The inhibitory effect of the extracts on the strains of P. aeruginosa tested demonstrated that Tabebuia impetiginosa and Maytenus macrocarpa possess higher antibacterial activity. Conclusions: The results of the present study scientifically validate the inhibitory capacity of the five medicinal plants attributed by their common use in folk medicine and contribute towards the development of new treatment options based on natural products.
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    • Arboviruses emerging in Peru: need for early detection of febrile syndrome during El Niño episodes

      Tantaléan Yépez, Derek; Sánchez-Carbonel, José; Ulloa Urizar, Gabriela; Aguilar Luis, Miguel Angel; Espinoza Morales, Diego; Silva-Caso, Wilmer; Pons, Maria J; Del Valle Mendoza, Juana; derek.2007.upc@gmail.com (Elsevier B.V., 2016-07)
      The presence of El Niño Southern Oscillation (ENSO) implies the presence of fluctuating rains in coastal areas and these changes influence the occurrence of febrile syndromes outbreaks. In Peru, Aedes aegypti is the vector responsible for various viruses such as the dengue, Zika, chikungunya, which is distributed in 18 Peruvian departments. These viruses cause similar clinical characteristics in the host and for this reason rapid, sensitive and specific diagnostic tests are needed so that the patient can receive timely treatment.
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