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dc.contributor.authorGomes, Cláudia*
dc.contributor.authorMartínez Puchol, Sandra*
dc.contributor.authorPalma, Noemí*
dc.contributor.authorHorna, Gertrudis*
dc.contributor.authorRuiz-Roldán, Lidia*
dc.contributor.authorPons, Maria J*
dc.contributor.authorRuiz, Joaquim*
dc.date.accessioned2016-10-28T23:33:20Z
dc.date.available2016-10-28T23:33:20Z
dc.date.issued2016-10-27
dc.identifier.citation1. Gomes C, Martínez-puchol S, Palma N, Horna G, Ruiz-roldán L, Pons MJ, et al. Critical Reviews in Microbiology Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin. Crit Rev Microbiol [Internet]. Informa Healthcare USA, Inc; 2016;0(0):000. Available from: http://dx.doi.org/10.3109/1040841X.2015.1136261es_PE
dc.identifier.issn1040-841X
dc.identifier.issn1549-7828
dc.identifier.doi10.3109/1040841X.2015.1136261
dc.identifier.urihttp://hdl.handle.net/10757/620710es_PE
dc.description.abstractFrom its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Grampositive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bacteria. Some of them, as azithromycin, are considered in the armamentarium against Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics to fight against Enterobacteriaceae infections. The present review is focused on the mechanisms of macrolide resistance, currently described in Enterobacteriaceae.
dc.description.sponsorshipCG has a PhD fellowship of the ISCIII [grant number: FI12/ 00561]. GH has a PhD fellowship from the Schlumberger Foundation – Faculty for The Future Program. LR-R has a PhD fellowship from Sistema Riojano de Innovaci on del Gobierno de La Rioja. MJP has a postdoctoral fellowship from CONCYTEC [grant number: CG05-2013-FONDECYT]. JR has a fellowship from the program I3, of the ISCIII [grant number: CES11/012]. The study was supported by the Generalitat de Catalunya, Departament d’Universitats, Recerca i Societat de la Informaci o [2014 SGR 26] and by the Spanish Network for the Research in Infectious Diseases [REIPI RD12/0015].es_PE
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherTaylor & Francises_PE
dc.relation.urlhttps://www.tandfonline.com/doi/full/10.3109/1040841X.2015.1136261es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subject23S rRNAes_PE
dc.subjectMethylaseses_PE
dc.subjectEsteraseses_PE
dc.subjectPhospotransferases;es_PE
dc.subjectRibosomal mutationses_PE
dc.titleMacrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycines_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.journalCritical Reviews in Microbiologyes_PE
dc.description.peerreviewRevisión por pareses_PE
dc.contributor.emailjoruiz.trabajo@gmail.comes_PE
refterms.dateFOA2018-06-18T21:43:47Z
html.description.abstractFrom its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Grampositive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bacteria. Some of them, as azithromycin, are considered in the armamentarium against Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics to fight against Enterobacteriaceae infections. The present review is focused on the mechanisms of macrolide resistance, currently described in Enterobacteriaceae.


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