• English
    • español
  • English 
    • English
    • español
  • Login
View Item 
  •   Home
  • Artículos científicos
  • Pregrado
  • Facultad de Ciencias de la Salud
  • Medicina
  • View Item
  •   Home
  • Artículos científicos
  • Pregrado
  • Facultad de Ciencias de la Salud
  • Medicina
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Browse

All of UPCCommunitiesTitleAuthorsAdvisorIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsAdvisorIssue DateSubmit DateSubjectsProfilesView

My Account

LoginRegister

Quick Guides

Acerca del COVID-19Acerca del RepositorioPolítica del RepositorioPlantillas WordFormato de publicación de tesis Formato de publicación de artículosFormato de publicación de otros documentosLista de verificaciónGuía para generar código ORCID en UPCRecursos en línea de tesisGuia del Repositorio Académico

Statistics

Display statistics

Risk factors for recurrent Clostridium difficile infection: a systematic review and meta-analysis.

  • CSV
  • RefMan
  • EndNote
  • BibTex
  • RefWorks
Average rating
 
   votes
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item. When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
 
Your vote was cast
Thank you for your feedback
Authors
Deshpande, Abhishek
Pasupuleti, Vinay
Thota, Priyaleela
Pant, Chaitanya
Rolston, David D K
Hernandez, Adrian V.
Donskey, Curtis J
Fraser, Thomas G
Issue Date
2015-04
Keywords
Clostridium difficile
Enterocolitis
Humans
Recurrence
Risk Factors
MeSH
Clostridium difficile
Enterocolitis, Pseudomembranous
Humans
Recurrence
Risk Factors

Metadata
Show full item record
Citation
Risk factors for recurrent Clostridium difficile infection: a systematic review and meta-analysis. 2015, 36 (4):452-60 Infect Control Hosp Epidemiol
Publisher
Cambridge University Press
Journal
Infection control and hospital epidemiology (Infect Control Hosp Epidemiol)
URI
http://hdl.handle.net/10757/608263
DOI
10.1017/ice.2014.88
PubMed ID
25626326
Additional Links
http://www.ncbi.nlm.nih.gov/pubmed/25626326
Abstract
OBJECTIVE: An estimated 20-30% of patients with primary Clostridium difficile infection (CDI) develop recurrent CDI (rCDI) within 2 weeks of completion of therapy. While the actual mechanism of recurrence remains unknown, a variety of risk factors have been suggested and studied. The aim of this systematic review and meta-analysis was to evaluate current evidence on the risk factors for rCDI. DESIGN: We searched MEDLINE and 5 other databases for subject headings and text related to rCDI. All studies investigating risk factors of rCDI in a multivariate model were eligible. Information on study design, patient population, and assessed risk factors were collected. Data were combined using a random-effects model and pooled relative risk ratios (RRs) were calculated. RESULTS: A total of 33 studies (n=18,530) met the inclusion criteria. The most frequent independent risk factors associated with rCDI were age≥65 years (risk ratio [RR], 1.63; 95% confidence interval [CI], 1.24-2.14; P=.0005), additional antibiotics during follow-up (RR, 1.76; 95% CI, 1.52-2.05; P<.00001), use of proton-pump inhibitors (PPIs) (RR, 1.58; 95% CI, 1.13-2.21; P=.008), and renal insufficiency (RR, 1.59; 95% CI, 1.14-2.23; P=.007). The risk was also greater in patients previously on fluoroquinolones (RR, 1.42; 95% CI, 1.28-1.57; P<.00001). CONCLUSIONS: Multiple risk factors are associated with the development of rCDI. Identification of modifiable risk factors and judicious use of antibiotics and PPI can play an important role in the prevention of rCDI.
Type
info:eu-repo/semantics/article
Rights
info:eu-repo/semantics/openAccess
Language
eng
Description
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
ISSN
1559-6834
ae974a485f413a2113503eed53cd6c53
10.1017/ice.2014.88
Scopus Count
Collections
Medicina

entitlement

Related articles

  • Recurrent <i>Clostridium difficile</i> Infection: Risk Factors, Treatment, and Prevention.
  • Authors: Song JH, Kim YS
  • Issue date: 2019 Jan 15
  • Risk factors for recurrent Clostridium difficile infection in hematopoietic stem cell transplant recipients.
  • Authors: Huang AM, Marini BL, Frame D, Aronoff DM, Nagel JL
  • Issue date: 2014 Oct
  • Recurrence of Clostridium difficile Infection in Patients with Inflammatory Bowel Disease: The RECIDIVISM Study.
  • Authors: Razik R, Rumman A, Bahreini Z, McGeer A, Nguyen GC
  • Issue date: 2016 Aug
  • Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics: meta-analysis.
  • Authors: Kwok CS, Arthur AK, Anibueze CI, Singh S, Cavallazzi R, Loke YK
  • Issue date: 2012 Jul
  • Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis.
  • Authors: Trifan A, Stanciu C, Girleanu I, Stoica OC, Singeap AM, Maxim R, Chiriac SA, Ciobica A, Boiculese L
  • Issue date: 2017 Sep 21

DSpace software (copyright © 2002 - 2021)  DuraSpace
Quick Guide | Contact Us
Alicia
La Referencia
Open Repository is a service operated by 
Atmire NV
 

Export search results

The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.