Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms
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Issue Date
2015-05-20
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Elsevier B.V.Journal
Asian Pacific Journal of Tropical Medicine (Asian Pacific Journal of Tropical Medicine)DOI
10.1016/S1995-7645(14)60361-8Additional Links
https://www.researchgate.net/publication/276831508_Characterization_of_two_Achromobacter_xyloxosidans_isolates_from_patients_with_pertussis-like_symptomsAbstract
Objective: To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance program. Methods: Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and PCR. Results: Two Achromobacter xylosoxidans A8, closely related to Bordetella spp. were recovered from 2 patients diagnosed of pertussis, both carrying the ptxA gene and IS418 the pertussis toxin encoding gene. Subsequently, antibiotic susceptibility was evaluated by disk-diffusion method and by PCR. Conclusions: Although more detailed studies are needed, the present data highlight the possibility that Achromobacter xylosoxidans, closely related Bordetella pertussis microorganisms and not covered under the vaccine umbrella, might also result in cases of whooping cough. Thereby further surveillance is necessary to determine the extension and relevance of their pathogenic role in order to discriminate their real public health implication.Type
info:eu-repo/semantics/articleRights
info:eu-repo/semantics/openAccessLanguage
engDescription
joruiz@clinic.ub.esISSN
1995-7645ae974a485f413a2113503eed53cd6c53
10.1016/S1995-7645(14)60361-8
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