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Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes

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2014 HPV mujeres asintomáticas.pdf
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Authors
Silva-Caso, Wilmer
Olivera Irazábal, Miluska
León Álvarez, Pedro
Del Valle, Luis J.
Díaz Estacio, Sonia
Vargas, Martha
Ruiz, Joaquim
Bermúdez García, Alejandro
Del Valle Mendoza, Juana
Issue Date
2014-11-20
Keywords
Human papillomavirus
Papanicolaou cervical cancer

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Citation
1. Silva-Caso W, Olivera-Irazábal M, León-Álvarez P, del Valle LJ, Díaz-Estacio S, Vargas M, et al. Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes. Asian Pacific Journal of Tropical Medicine. septiembre de 2014;7, Supplement 1:S121-6.
Publisher
Elsevier B.V.
URI
http://hdl.handle.net/10757/335866
DOI
10.1016/S1995-7645(14)60217-0
Additional Links
http://www.sciencedirect.com/science/article/pii/S1995764514602170
Type
info:eu-repo/semantics/article
Rights
info:eu-repo/semantics/openAccess
Language
eng
Description
Objective: To detect the most prevalent human papillomavirus (HPV) genotypes samples of asymptomatic Peruvian women by analyzing the correlation betwe ienn c Pearvpiacnailc somlaeoaur (PAP)-stained cervical tests and PCR-sequencing. Methods: A total of 254 women attending routine gynecological examinations were included in pthaitsh ostluogdiys.t Tahned scalmaspsliefise dw ebrye tahnea Blyeztehde sbdya PsAysPt etmec.h HnPiqVu ea manpdli feicxaatmioinn ewda su nddoenre au msinicgr othsceo pprei mbeyr as specific for E1 region and positive specimens were confirmed by direct sequencing. Results: The prevalence of HPV was investigated in 254 cervical scrape samples by PCR. PAP smear showed that 94.9% cases had normal morphology and 5.1% had an inflammatory pattern; 2p0r.e5v%a lwenert eg efonuontydp teo ibne c ionrfreeclatetido nw iwthit hH PchVa, ncgoems pinri scienrgv i2c0a dl icfyfetorelongt yg.enotypes. HPV16 was the most Conclusions: Our results suggest the HPV is very frequent even in women with negative PAP, eannddo PceCrRvi csaele smasm tpol ebs.e Itdheen tbifeicsat toiopnt ioofn t htoe HdePtVe rgmeinnoety tphee inc aaussyamtipvteo magateinc tw oofm HePnV m ianyf eaclltoiown t hine nimatpulreaml henisttaotriyo no fo tfh ea pdpisroepasreia aten dp rthope hsyulbascetqicu emnet adseuvreelso pwmheicnht omf acye rhviacvael ma adliirgencatn icmy.pact
[email protected]
ISSN
1995-7645
Sponsors
This work has been partially supported by Universidad Peruana de Ciencias Aplicadas (UPC), Instituto de Investigación Nutricional and Instituto de Investigación de Efrnomfe rtmheed pardoegsr aImnf ecciosas, Lima, Peru. JR has a fellowship I3, of the ISCIII (Grant No. CES11/012), and LJDV from the Generalitat de Catalunya (2009SGR1208).
ae974a485f413a2113503eed53cd6c53
10.1016/S1995-7645(14)60217-0
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Medicina

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