Características de las úlceras gastroduodenales en pacientes con biopsia negativa para Helicobacter pylori.
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Issue Date
2014-03-24Keywords
Úlcera pépticaHelicobacter pylori
metaplasia intestinal
Peptic ulcer
Helicobacter pylori
intestinal metaplasia
Metadata
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Characteristics of gastroduodenal ulcers in patients with negative biopsies for Helicobacter pylori.Citation
Acta Gastroenterol Latinoam 2010;40:40-45Publisher
Sociedad Argentina de GastroenterologíaAdditional Links
http://www.redalyc.org/articulo.oa?id=199314640008Abstract
Objetives. To evaluate the clinical, epidemiological and endoscopic characteristics of the Helicobacter pylori (Hp) negative peptic ulcer disease. Methods. In this cross sectional study we included 651 patients diagnosed of peptic ulcer disease between January 2000 and December 2005. The diagnosis of Hp infection was established by histology. Clinical and epidemiological characteristics of patients with and without Hp infection were compared. Results. Males prevailed (69%). Hp negative ulcers were older (57,73 +/- 19,44 years old vs 50,26 +/- 18, 64 years old, P < 0.001). Clinical characteristics did not differ among both groups. Duodenal ulcer prevailed in Hp positive patients (56,5%) and gastric ulcer in Hp negative patients (53,5%). Multiple ulcers and intestinal metaplasia were more frequently found in Hp negative cases [9.3% vs 4.5 % (P = 0,015) and 34.5% vs 22.1% (P = 0,001), respectively]. Conclusion. Hp negative peptic ulcer disease is found in older patients, with a higher frequency of gastric ulcers, multiple lesions and intestinal metaplasia.Type
info:eu-repo/semantics/articleRights
info:eu-repo/semantics/openAccessLanguage
spaISSN
0300-9033Collections