Utility of TG/HDL-c ratio as a predictor of mortality and cardiovascular disease in patients with chronic kidney disease undergoing hemodialysis: A systematic review
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Autor
Gonzáles-Rubianes, Diana ZolansFigueroa-Osorio, Liz Katerin
Benites-Zapata, Vicente A.
Pacheco-Mendoza, Josmel
Herrera-Añazco, Percy
Fecha de publicación
2022-04-01
Metadatos
Mostrar el registro completo del ítemEditorial
John Wiley and Sons IncJournal
Hemodialysis InternationalDOI
10.1111/hdi.12981Enlaces adicionales
https://onlinelibrary.wiley.com/doi/10.1111/hdi.12981Resumen
The triglyceride/high-density cholesterol-lipoprotein (TG/HDL-c) is a biomarker of cardiovascular events and mortality. In hemodialysis patients, the evidence is controversial. A systematic review was carried out in the Medline, Scopus, Embase, Web of Science, and Pubmed databases to identify the relevant cohort studies on cardiovascular events and mortality in hemodialysis patients the role of TG/HDL-c as a risk factor. Four cohort-type studies were evaluated, with a total of 52,579 hemodialysis patients. Three studies conducted in Asian populations and one study in the United States had the highest percentage of the sample (50,673 patients). The elevated TG/HDL-c ratio is associated with better survival, and there is a consistent gradual inverse association between TG/HDL-c and mortality in all analysis subgroups. In the decile categorization of the exposure variable, a 21% decrease in the risk of cardiovascular mortality and a 15% decrease in all-cause mortality in the highest decile compared to the reference group (D10 aHR = 0.79; 95% CI: 0.69–0.91 and D10 aHR = 0.85; 95%CI: 0.78–0.92). Our results show that the TG/HDL-c ratio is a protective factor for cardiovascular outcomes and mortality in the American population and a risk factor for them in the population from Asia.Tipo
info:eu-repo/semantics/articleDerechos
info:eu-repo/semantics/embargoedAccessIdioma
engISSN
14927535EISSN
15424758ae974a485f413a2113503eed53cd6c53
10.1111/hdi.12981
Scopus Count
Colecciones