Association Between Endometriosis and Preterm Birth in Women With Spontaneous Conception or Using Assisted Reproductive Technology: A Systematic Review and Meta-Analysis of Cohort Studies

2.50
Hdl Handle:
http://hdl.handle.net/10757/622972
Title:
Association Between Endometriosis and Preterm Birth in Women With Spontaneous Conception or Using Assisted Reproductive Technology: A Systematic Review and Meta-Analysis of Cohort Studies
Authors:
Pérez-López, Faustino R.; Villagrasa-Boli, Pablo; Muñoz-Olarte, María; Morera-Grau, Álex; Cruz-Andrés, Pablo; Hernandez, Adrian V. ( 0000-0002-9999-4003 )
Citation:
Association Between Endometriosis and Preterm Birth in Women With Spontaneous Conception or Using Assisted Reproductive Technology: A Systematic Review and Meta-Analysis of Cohort Studies 2018, 25 (3):311 Reproductive Sciences
Publisher:
SAGE Publications Inc.
Journal:
Reproductive Sciences
Issue Date:
5-Jan-2018
URI:
http://hdl.handle.net/10757/622972
DOI:
10.1177/1933719117749760
Additional Links:
http://journals.sagepub.com/doi/10.1177/1933719117749760
Abstract:
OBJECTIVE: To perform a systematic review and meta-analysis to estimate the effect of endometriosis on preterm birth (PB) risk. METHODS: Searches were conducted in PubMed-MEDLINE, Embase, Scopus, Web of Science, Cochrane Library, Google Scholar, and SciELO for studies published in all languages from inception through April 2017. We included cohort studies evaluating pregnant women with and without endometriosis and conception either by spontaneous conception (SC) or with assisted reproductive technology (ART). Primary outcome was PB (<37 weeks), and secondary outcomes were intrauterine growth restriction (IUGR), low birthweight, small for gestational age (SGA), and birthweight. Pooled odds ratios (ORs) and its 95% confidence interval (CI) were calculated as effects, and random-effects models were used for meta-analyses. Risk of bias was assessed with the Newcastle-Ottawa Scale, and heterogeneity of effects among studies was described with the I2 statistic. RESULTS: We identified 9 cohort studies including a total of 1 496 715 pregnancies (13 798 with endometriosis diagnosis). In women with endometriosis, the PB risk was significantly increased in both SC (OR: 1.59; 95% CI: 1.32-1.90) and ART (OR: 1.43; 95% CI: 1.14-1.79). The SGA risk was increased in women with endometriosis (OR: 1.16; 95% CI: 1.05-1.28), while the IUGR and low birthweight risks and birthweight were not affected by endometriosis. CONCLUSION: Endometriosis is associated with increased PB risk in both SC and women who obtained pregnancy using ART. Prospective studies evaluating relevant outcomes are needed to confirm these results.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/restrictedAccess
Language:
eng
Description:
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
Keywords:
Assisted reproductive technology; Birthweight; Endometriosis; Infertility; Meta-analysis; Preterm birth; Small for gestational age; Spontaneous conception
ISSN:
1933-7191; 1933-7205

Full metadata record

DC FieldValue Language
dc.contributor.authorPérez-López, Faustino R.es
dc.contributor.authorVillagrasa-Boli, Pabloes
dc.contributor.authorMuñoz-Olarte, Maríaes
dc.contributor.authorMorera-Grau, Álexes
dc.contributor.authorCruz-Andrés, Pabloes
dc.contributor.authorHernandez, Adrian V.es
dc.date.accessioned2018-03-20T12:59:47Z-
dc.date.available2018-03-20T12:59:47Z-
dc.date.issued2018-01-05-
dc.identifier.citationAssociation Between Endometriosis and Preterm Birth in Women With Spontaneous Conception or Using Assisted Reproductive Technology: A Systematic Review and Meta-Analysis of Cohort Studies 2018, 25 (3):311 Reproductive Scienceses
dc.identifier.issn1933-7191-
dc.identifier.issn1933-7205-
dc.identifier.doi10.1177/1933719117749760-
dc.identifier.urihttp://hdl.handle.net/10757/622972-
dc.descriptionEl texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.es
dc.description.abstractOBJECTIVE: To perform a systematic review and meta-analysis to estimate the effect of endometriosis on preterm birth (PB) risk. METHODS: Searches were conducted in PubMed-MEDLINE, Embase, Scopus, Web of Science, Cochrane Library, Google Scholar, and SciELO for studies published in all languages from inception through April 2017. We included cohort studies evaluating pregnant women with and without endometriosis and conception either by spontaneous conception (SC) or with assisted reproductive technology (ART). Primary outcome was PB (<37 weeks), and secondary outcomes were intrauterine growth restriction (IUGR), low birthweight, small for gestational age (SGA), and birthweight. Pooled odds ratios (ORs) and its 95% confidence interval (CI) were calculated as effects, and random-effects models were used for meta-analyses. Risk of bias was assessed with the Newcastle-Ottawa Scale, and heterogeneity of effects among studies was described with the I2 statistic. RESULTS: We identified 9 cohort studies including a total of 1 496 715 pregnancies (13 798 with endometriosis diagnosis). In women with endometriosis, the PB risk was significantly increased in both SC (OR: 1.59; 95% CI: 1.32-1.90) and ART (OR: 1.43; 95% CI: 1.14-1.79). The SGA risk was increased in women with endometriosis (OR: 1.16; 95% CI: 1.05-1.28), while the IUGR and low birthweight risks and birthweight were not affected by endometriosis. CONCLUSION: Endometriosis is associated with increased PB risk in both SC and women who obtained pregnancy using ART. Prospective studies evaluating relevant outcomes are needed to confirm these results.es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherSAGE Publications Inc.es
dc.relation.urlhttp://journals.sagepub.com/doi/10.1177/1933719117749760es
dc.rightsinfo:eu-repo/semantics/restrictedAccesses
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Academico - UPCes_PE
dc.subjectAssisted reproductive technologyes
dc.subjectBirthweightes
dc.subjectEndometriosises
dc.subjectInfertilityes
dc.subjectMeta-analysises
dc.subjectPreterm birthes
dc.subjectSmall for gestational agees
dc.subjectSpontaneous conceptiones
dc.titleAssociation Between Endometriosis and Preterm Birth in Women With Spontaneous Conception or Using Assisted Reproductive Technology: A Systematic Review and Meta-Analysis of Cohort Studieses
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.journalReproductive Scienceses
dc.contributor.institutionFacultad de Medicina, Universidad de Zaragoza, Red de Investigación en Ginecología, Obstetricia y Reproducción, Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain-
dc.contributor.institutionFacultad de Medicina, Universidad de Zaragoza, Red de Investigación en Ginecología, Obstetricia y Reproducción, Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain-
dc.contributor.institutionFacultad de Medicina, Universidad de Zaragoza, Red de Investigación en Ginecología, Obstetricia y Reproducción, Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain-
dc.contributor.institutionFacultad de Medicina, Universidad de Zaragoza, Red de Investigación en Ginecología, Obstetricia y Reproducción, Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain-
dc.contributor.institutionFacultad de Medicina, Universidad de Zaragoza, Red de Investigación en Ginecología, Obstetricia y Reproducción, Instituto Aragonés de Ciencias de la Salud (IACS), Zaragoza, Spain-
dc.contributor.institutionSchool of Medicine, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru-
dc.description.peerreviewRevisión por pareses_PE
All Items in UPC are protected by copyright, with all rights reserved, unless otherwise indicated.