Emerging and reemerging arboviruses: A new threat in Eastern Peru

2.50
Hdl Handle:
http://hdl.handle.net/10757/622421
Title:
Emerging and reemerging arboviruses: A new threat in Eastern Peru
Authors:
Alva-Urcia, Carlos; Aguilar-Luis, Miguel Angel; Palomares-Reyes, Carlos; Silva-Caso, Wilmer; Suarez-Ognio, Luis; Weilg, Pablo; Manrique, Carlos; Vasquez-Achaya, Fernando; del Valle, Luis J.; del Valle-Mendoza, Juana ( 0000-0002-6011-5040 )
Citation:
Emerging and reemerging arboviruses: A new threat in Eastern Peru 2017, 12 (11):e0187897 PLOS ONE
Publisher:
Public Library of Science (PLoS)
Journal:
PLOS ONE
Issue Date:
14-Nov-2017
URI:
http://hdl.handle.net/10757/622421
DOI:
10.1371/journal.pone.0187897
Additional Links:
http://dx.plos.org/10.1371/journal.pone.0187897
Abstract:
Background Arboviral diseases are one of the most common causes of acute febrile illness (AFI) and a significant health problem in South America. In Peru, laboratory etiologic identification of these infections occurs in less than 50% of cases, leading to underdiagnoses of important emerging arboviruses. Aim To assess the prevalence of the Dengue (DENV), Oropouche (OROV), Chikungunya (CHIKV), Mayaro (MAYV) and Zika (ZIKV) viruses in patients with acute febrile illness from Puerto Maldonado (Peru). Methodology Serum samples were obtained from patients with AFI during January 2016 to March 2016. A total of 139 specimens were analyzed for the presence of DENV, OROV, CHIKV, MAYV, and ZIKV using polymerase chain reaction (PCR). Results CHIKV in 9.4% and OROV in 8.6% were the most prevalent arboviruses, followed by DENV and ZIKV, with a prevalence of 6.5% and 5%, respectively. Among all patients, the most common symptoms accompanying fever were headaches 79.9%, muscle pain 65.5% and joint pain 63.3%. Conclusions During this short 3-month period, 4 arboviruses were detected by PCR, CHIKV and OROV being the most common arboviruses in Puerto Maldonado (Peru). Thus, it is crucial to include OROV detection in the national health surveillance. Furthermore, the etiologic clinical diagnosis of arboviral infections is not possible due to the low specificity of symptoms; therefore an increase of cases confirmed by molecular diagnostic methods will enhance arboviral surveillance in Peru.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Keywords:
Chikungunya virus; Arboviral infections; Arboviruses; Myalgia; Peru; Zika virus; Headaches; Chikungunya infect
ISSN:
1932-6203
Email:
jdelvall@upc.edu.pe

Full metadata record

DC FieldValue Language
dc.contributor.authorAlva-Urcia, Carloses
dc.contributor.authorAguilar-Luis, Miguel Angeles
dc.contributor.authorPalomares-Reyes, Carloses
dc.contributor.authorSilva-Caso, Wilmeres
dc.contributor.authorSuarez-Ognio, Luises
dc.contributor.authorWeilg, Pabloes
dc.contributor.authorManrique, Carloses
dc.contributor.authorVasquez-Achaya, Fernandoes
dc.contributor.authordel Valle, Luis J.es
dc.contributor.authordel Valle-Mendoza, Juanaes
dc.date.accessioned2017-11-17T21:29:30Z-
dc.date.available2017-11-17T21:29:30Z-
dc.date.issued2017-11-14-
dc.identifier.citationEmerging and reemerging arboviruses: A new threat in Eastern Peru 2017, 12 (11):e0187897 PLOS ONEes
dc.identifier.issn1932-6203-
dc.identifier.doi10.1371/journal.pone.0187897-
dc.identifier.urihttp://hdl.handle.net/10757/622421-
dc.description.abstractBackground Arboviral diseases are one of the most common causes of acute febrile illness (AFI) and a significant health problem in South America. In Peru, laboratory etiologic identification of these infections occurs in less than 50% of cases, leading to underdiagnoses of important emerging arboviruses. Aim To assess the prevalence of the Dengue (DENV), Oropouche (OROV), Chikungunya (CHIKV), Mayaro (MAYV) and Zika (ZIKV) viruses in patients with acute febrile illness from Puerto Maldonado (Peru). Methodology Serum samples were obtained from patients with AFI during January 2016 to March 2016. A total of 139 specimens were analyzed for the presence of DENV, OROV, CHIKV, MAYV, and ZIKV using polymerase chain reaction (PCR). Results CHIKV in 9.4% and OROV in 8.6% were the most prevalent arboviruses, followed by DENV and ZIKV, with a prevalence of 6.5% and 5%, respectively. Among all patients, the most common symptoms accompanying fever were headaches 79.9%, muscle pain 65.5% and joint pain 63.3%. Conclusions During this short 3-month period, 4 arboviruses were detected by PCR, CHIKV and OROV being the most common arboviruses in Puerto Maldonado (Peru). Thus, it is crucial to include OROV detection in the national health surveillance. Furthermore, the etiologic clinical diagnosis of arboviral infections is not possible due to the low specificity of symptoms; therefore an increase of cases confirmed by molecular diagnostic methods will enhance arboviral surveillance in Peru.es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherPublic Library of Science (PLoS)es
dc.relation.urlhttp://dx.plos.org/10.1371/journal.pone.0187897es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectChikungunya viruses
dc.subjectArboviral infectionses
dc.subjectArboviruseses
dc.subjectMyalgiaes
dc.subjectPerues
dc.subjectZika viruses
dc.subjectHeadacheses
dc.subjectChikungunya infectes
dc.titleEmerging and reemerging arboviruses: A new threat in Eastern Perues
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.journalPLOS ONEes
dc.description.peerreviewRevisión por pareses
dc.contributor.emailjdelvall@upc.edu.pees_PE
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