Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.

2.50
Hdl Handle:
http://hdl.handle.net/10757/622325
Title:
Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.
Authors:
Phan, Tung Gia; Del Valle Mendoza, Juana Mercedes ( 0000-0002-6011-5040 ) ; Sadeghi, Mohammadreza; Altan, Eda; Deng, Xutao; Delwart, Eric
Citation:
Sera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. 2017 Virus Genes
Publisher:
Springer International Publishing
Journal:
Virus genes
Issue Date:
17-Oct-2017
URI:
http://hdl.handle.net/10757/622325
DOI:
10.1007/s11262-017-1514-3
PubMed ID:
29043660
Additional Links:
https://www.ncbi.nlm.nih.gov/pubmed/?term=29043660%5Buid%5D
Abstract:
Serum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample. The detection in human serum of nucleic acids from viral families not known to infect vertebrates may indicate contamination during sample collection and aliquoting or human infection by their presumed cellular host, here a fungus. The role, if any, of the non-vertebrate infecting viruses detected in serum in inducing fever is unknown.
Type:
info:eu-repo/semantics/article
Rights:
Archived with thanks to Virus genes
Language:
eng
Description:
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
Keywords:
Dicistrovirus; Fever; Metagenomics; Partitivirus
ISSN:
1572-994X

Full metadata record

DC FieldValue Language
dc.contributor.authorPhan, Tung Giaes
dc.contributor.authorDel Valle Mendoza, Juana Mercedeses
dc.contributor.authorSadeghi, Mohammadrezaes
dc.contributor.authorAltan, Edaes
dc.contributor.authorDeng, Xutaoes
dc.contributor.authorDelwart, Erices
dc.date.accessioned2017-10-27T19:53:47Z-
dc.date.available2017-10-27T19:53:47Z-
dc.date.issued2017-10-17-
dc.identifier.citationSera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts. 2017 Virus Geneses
dc.identifier.issn1572-994X-
dc.identifier.pmid29043660-
dc.identifier.doi10.1007/s11262-017-1514-3-
dc.identifier.urihttp://hdl.handle.net/10757/622325-
dc.descriptionEl texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.es
dc.description.abstractSerum samples collected from 88 Peruvians with unexplained fever were analyzed for viral sequences using metagenomics. Nucleic acids of anelloviruses, pegivirus A (GBV-C), HIV, Dengue virus, and Oropouche virus were detected. We also characterized from two sera the RNA genomes of new species of partitivirus and dicistrovirus belonging to viral families known to infect fungi or arthropod, respectively. Genomic DNA of a putative fungal cellular host could be PCR amplified from the partitivirus-containing serum sample. The detection in human serum of nucleic acids from viral families not known to infect vertebrates may indicate contamination during sample collection and aliquoting or human infection by their presumed cellular host, here a fungus. The role, if any, of the non-vertebrate infecting viruses detected in serum in inducing fever is unknown.es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherSpringer International Publishinges
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/?term=29043660%5Buid%5Des
dc.rightsArchived with thanks to Virus geneses
dc.subjectDicistroviruses
dc.subjectFeveres
dc.subjectMetagenomicses
dc.subjectPartitiviruses
dc.titleSera of Peruvians with fever of unknown origins include viral nucleic acids from non-vertebrate hosts.es
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.journalVirus geneses
dc.description.peerreviewRevisión por pareses_PE

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