Prevalence of chronic kidney disease in Peruvian primary care setting.

2.50
Hdl Handle:
http://hdl.handle.net/10757/622208
Title:
Prevalence of chronic kidney disease in Peruvian primary care setting.
Authors:
Herrera-Añazco, Percy; Taype-Rondan, Alvaro; Lazo-Porras, María; Alberto Quintanilla, E; Ortiz-Soriano, Victor Manuel; Hernandez, Adrian V. ( 0000-0002-9999-4003 )
Citation:
Prevalence of chronic kidney disease in Peruvian primary care setting. 2017, 18 (1):246 BMC Nephrol
Publisher:
BMJ Publishing Group Ltd
Journal:
BMC Nephrology
Issue Date:
19-Jul-2017
URI:
http://hdl.handle.net/10757/622208
DOI:
10.1186/s12882-017-0655-x
PubMed ID:
28724362
Additional Links:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517816/
Abstract:
Background: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. Methods: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO). Factors associated with CKD were evaluated with Poisson Regression models; these factors included age, gender, type 2 diabetes mellitus (DM2), hypertension (HTN), body mass index (BMI), and uric acid. Associations were described as crude and adjusted prevalence ratios (PR) and their 95% confidence intervals (95% CI). Results: We evaluated 1211 patients (women [59%], mean age 65.8 years [SD: 12.7]). Prevalence of CKD was 18%. Using the estimated glomerular filtration rate (eGFR), the prevalence was 9.3% (95% CI 5.3 – 13.3) in patients without HTN or DM2; 20.2% (95% CI 17.6 – 22.8) in patients with HTN, and 23.9% (95% CI 19.4 – 28.4) in patients with DM2. The most common stages were 1 and 2 with 41.5% and 48%, respectively. Factors associated with CKD in the adjusted analysis were: age in years (PR = 1.03, 95% CI 1.01 – 1.04), DM2 (PR = 3.37, 95% CI 1.09 – 10.39), HTN plus DM2 (PR = 3.90, 95% CI 1.54 – 9.88), and uric acid from 5 to <7 mg/dL (PR = 2.04, 95% CI 1.31 – 3.19) and ≥7 mg/dL (PR = 5.19, 95% CI 3.32 – 8.11). Conclusions: Prevalence of CKD in the primary care setting population was high. CKD is more frequent in the early stages of the disease, and individuals with hypertension, DM2, older age and hyperuricemia have higher prevalence of CKD.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Keywords:
Chronic Kidney Disease; Latin America; Diabetes; Hypertension; Elderly; Hyperuricemia
ISSN:
1471-2369
Email:
moc.liamg@dumalis

Full metadata record

DC FieldValue Language
dc.contributor.authorHerrera-Añazco, Percyes
dc.contributor.authorTaype-Rondan, Alvaroes
dc.contributor.authorLazo-Porras, Maríaes
dc.contributor.authorAlberto Quintanilla, Ees
dc.contributor.authorOrtiz-Soriano, Victor Manueles
dc.contributor.authorHernandez, Adrian V.es
dc.date.accessioned2017-10-09T15:15:56Z-
dc.date.available2017-10-09T15:15:56Z-
dc.date.issued2017-07-19-
dc.identifier.citationPrevalence of chronic kidney disease in Peruvian primary care setting. 2017, 18 (1):246 BMC Nephroles
dc.identifier.issn1471-2369-
dc.identifier.pmid28724362-
dc.identifier.doi10.1186/s12882-017-0655-x-
dc.identifier.urihttp://hdl.handle.net/10757/622208-
dc.description.abstractBackground: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. Methods: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO). Factors associated with CKD were evaluated with Poisson Regression models; these factors included age, gender, type 2 diabetes mellitus (DM2), hypertension (HTN), body mass index (BMI), and uric acid. Associations were described as crude and adjusted prevalence ratios (PR) and their 95% confidence intervals (95% CI). Results: We evaluated 1211 patients (women [59%], mean age 65.8 years [SD: 12.7]). Prevalence of CKD was 18%. Using the estimated glomerular filtration rate (eGFR), the prevalence was 9.3% (95% CI 5.3 – 13.3) in patients without HTN or DM2; 20.2% (95% CI 17.6 – 22.8) in patients with HTN, and 23.9% (95% CI 19.4 – 28.4) in patients with DM2. The most common stages were 1 and 2 with 41.5% and 48%, respectively. Factors associated with CKD in the adjusted analysis were: age in years (PR = 1.03, 95% CI 1.01 – 1.04), DM2 (PR = 3.37, 95% CI 1.09 – 10.39), HTN plus DM2 (PR = 3.90, 95% CI 1.54 – 9.88), and uric acid from 5 to <7 mg/dL (PR = 2.04, 95% CI 1.31 – 3.19) and ≥7 mg/dL (PR = 5.19, 95% CI 3.32 – 8.11). Conclusions: Prevalence of CKD in the primary care setting population was high. CKD is more frequent in the early stages of the disease, and individuals with hypertension, DM2, older age and hyperuricemia have higher prevalence of CKD.us_US
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherBMJ Publishing Group Ltdes
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517816/es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectChronic Kidney Diseasees
dc.subjectLatin Americaes
dc.subjectDiabeteses
dc.subjectHypertensiones
dc.subjectElderlyes
dc.subjectHyperuricemiaes
dc.titlePrevalence of chronic kidney disease in Peruvian primary care setting.es
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.journalBMC Nephrologyes
dc.description.peerreviewRevisión por pareses_PE
dc.contributor.emailmoc.liamg@dumalises_PE

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