Migraine and the risk of post-traumatic stress disorder among a cohort of pregnant women

2.50
Hdl Handle:
http://hdl.handle.net/10757/622191
Title:
Migraine and the risk of post-traumatic stress disorder among a cohort of pregnant women
Authors:
Friedman, Lauren E.; Aponte, Christina; Perez Hernandez, Rigoberto; Velez, Juan Carlos; Gelaye, Bizu; Sánchez, Sixto E.; Williams, Michelle A.; Peterlin, B. Lee
Citation:
1. Friedman LE, Aponte C, Perez Hernandez R, Velez JC, Gelaye B, Sánchez SE, et al. Migraine and the risk of post-traumatic stress disorder among a cohort of pregnant women. J Headache Pain [Internet]. 2017;18(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021994275&doi=10.1186%2Fs10194-017-0775-5&partnerID=40&md5=8f5c40cea2acc427b2943c4d764b4c8d
Publisher:
Springer International Publishing
Journal:
The Journal of Headache and Pain
Issue Date:
6-Dec-2017
URI:
http://hdl.handle.net/10757/622191
DOI:
10.1186/s10194-017-0775-5
Additional Links:
http://thejournalofheadacheandpain.springeropen.com/articles/10.1186/s10194-017-0775-5
Abstract:
Background Individually both migraine and post-traumatic stress disorder (PTSD) prevalence estimates are higher among women. However, there is limited data on the association of migraine and PTSD in women during pregnancy. Methods We examined the association between migraine and PTSD among women attending prenatal clinics in Peru. Migraine was characterized using the International Classification of Headache Disorders (ICHD)-III beta criteria. PTSD was assessed using the PTSD Checklist-Civilian Version (PCL-C). Multivariable logistic regression analyses were performed to estimate odds ratios (OR) and 95% confidence intervals (CI) after adjusting for confounders. Results Of the 2922 pregnant women included, 33.5% fulfilled criteria for any migraine (migraine 12.5%; probable migraine 21.0%) and 37.4% fulfilled PTSD criteria. Even when controlling for depression, women with any migraine had almost a 2-fold increased odds of PTSD (OR: 1.97; 95% CI: 1.64–2.37) as compared to women without migraine. Specifically, women with migraine alone (i.e. excluding probable migraine) had a 2.85-fold increased odds of PTSD (95% CI: 2.18–3.74), and women with probable migraine alone had a 1.61-fold increased odds of PTSD (95% CI: 1.30–1.99) as compared to those without migraine, even after controlling for depression. In those women with both migraine and comorbid depression, the odds of PTSD in all migraine categories were even further increased as compared to those women without migraine. Conclusion In a cohort of pregnant women, irrespective of the presence or absence of depression, the odds of PTSD is increased in those with migraine. Our findings suggest the importance of screening for PTSD, specifically in pregnant women with migraine.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Keywords:
Migraine; Post-traumatic stress disorder PTSD Pregnancy
ISSN:
1129-2369; 1129-2377
Email:
lfriedm@hsph.harvard.edu

Full metadata record

DC FieldValue Language
dc.contributor.authorFriedman, Lauren E.es
dc.contributor.authorAponte, Christinaes
dc.contributor.authorPerez Hernandez, Rigobertoes
dc.contributor.authorVelez, Juan Carloses
dc.contributor.authorGelaye, Bizues
dc.contributor.authorSánchez, Sixto E.es
dc.contributor.authorWilliams, Michelle A.es
dc.contributor.authorPeterlin, B. Leees
dc.date.accessioned2017-10-05T20:27:04Z-
dc.date.available2017-10-05T20:27:04Z-
dc.date.issued2017-12-06-
dc.identifier.citation1. Friedman LE, Aponte C, Perez Hernandez R, Velez JC, Gelaye B, Sánchez SE, et al. Migraine and the risk of post-traumatic stress disorder among a cohort of pregnant women. J Headache Pain [Internet]. 2017;18(1). Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021994275&doi=10.1186%2Fs10194-017-0775-5&partnerID=40&md5=8f5c40cea2acc427b2943c4d764b4c8des
dc.identifier.issn1129-2369-
dc.identifier.issn1129-2377-
dc.identifier.doi10.1186/s10194-017-0775-5-
dc.identifier.urihttp://hdl.handle.net/10757/622191-
dc.description.abstractBackground Individually both migraine and post-traumatic stress disorder (PTSD) prevalence estimates are higher among women. However, there is limited data on the association of migraine and PTSD in women during pregnancy. Methods We examined the association between migraine and PTSD among women attending prenatal clinics in Peru. Migraine was characterized using the International Classification of Headache Disorders (ICHD)-III beta criteria. PTSD was assessed using the PTSD Checklist-Civilian Version (PCL-C). Multivariable logistic regression analyses were performed to estimate odds ratios (OR) and 95% confidence intervals (CI) after adjusting for confounders. Results Of the 2922 pregnant women included, 33.5% fulfilled criteria for any migraine (migraine 12.5%; probable migraine 21.0%) and 37.4% fulfilled PTSD criteria. Even when controlling for depression, women with any migraine had almost a 2-fold increased odds of PTSD (OR: 1.97; 95% CI: 1.64–2.37) as compared to women without migraine. Specifically, women with migraine alone (i.e. excluding probable migraine) had a 2.85-fold increased odds of PTSD (95% CI: 2.18–3.74), and women with probable migraine alone had a 1.61-fold increased odds of PTSD (95% CI: 1.30–1.99) as compared to those without migraine, even after controlling for depression. In those women with both migraine and comorbid depression, the odds of PTSD in all migraine categories were even further increased as compared to those women without migraine. Conclusion In a cohort of pregnant women, irrespective of the presence or absence of depression, the odds of PTSD is increased in those with migraine. Our findings suggest the importance of screening for PTSD, specifically in pregnant women with migraine.es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherSpringer International Publishinges
dc.relation.urlhttp://thejournalofheadacheandpain.springeropen.com/articles/10.1186/s10194-017-0775-5es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectMigrainees
dc.subjectPost-traumatic stress disorder PTSD Pregnancyes
dc.titleMigraine and the risk of post-traumatic stress disorder among a cohort of pregnant womenes
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.journalThe Journal of Headache and Paines
dc.description.fundingThis research was supported by awards from the National Institutes of Health (NIH), National Institute of Minority Health and Health Disparities (T37-MD- 001449), and the Eunice Kenney Shriver National Institute of Child Health and Human Development (R01-HD-059835). The NIH had no further role in study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication.es_PE
dc.description.peerreviewRevisión por pareses_PE
dc.contributor.emaillfriedm@hsph.harvard.edues_PE
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