Utilidad de la glicemia a la admisión en la unidad de cuidados intensivos pediátrica como predictor de mortalidad de los pacientes hospitalizados en el Instituto Nacional de Salud del Niño, 2012-2013

2.50
Hdl Handle:
http://hdl.handle.net/10757/621830
Title:
Utilidad de la glicemia a la admisión en la unidad de cuidados intensivos pediátrica como predictor de mortalidad de los pacientes hospitalizados en el Instituto Nacional de Salud del Niño, 2012-2013
Authors:
Toro Polo, Luis Miguel; Ortiz Lozada, Ricardo Yannick; Chang Grozo, Silvana Lucia
Advisors:
Solari Zerpa, Lely Del Rosario; Hernandez, Adrian V. ( 0000-0002-9999-4003 )
Publisher:
Universidad Peruana de Ciencias Aplicadas (UPC)
Issue Date:
8-Feb-2016
URI:
http://hdl.handle.net/10757/621830
Abstract:
Introduction. There is a high prevalence of mortality in the Pediatric Intensive Care Units (PICU) in developing countries. Association has been found between disglyce mia and mortality in the PICU; however, there is a lack of standardization of the utility of such ranges. Objectives. To analyze the association between glycemia levels in PICU admission and mortality in patients hospitalized at Instituto Nacional de Salud del Niño (INSN). Methods. Retrospective cohort in PICU patients admitted to INSN between 2012 and 2013. A Poisson regression model with robust variance was used to quantify the association. Diagnostic Test performance evaluation was used to describe sensitivit y, specificity, positive predictive value, negative predictive value and likelihood ratios for each range of glycemia. Results. 552 patients were included (Age range 5 to 79,8 months). The mean glycemia on admission was 121.3 mg/dL. Ninety two (16.6%) patients died during hospitalization. In multivariable analyses, significant associatio ns between glycemia <65 mg/dL (RR: 2.01, 95%CI 1.14-3.53), glycemia >200 mg/dL (RR: 2.91, 95%CI 1.71-4.55), malnutrition (RR: 1.53, 95%CI 1.04-2.25), mechanica l ventilation (RR: 3.71, 95%CI 1.17-11.76) and mortality at discharge were found. There was low sensitivity (between 17.39% and 39.13%) and high specificity (between 49.13% and 91.74%) for different glucose cut-off levels. Conclusions. There is an increased risk of death at discharge in patients who developed hypoglycemia and hyperglycemia on admission to the PICU. Certain glucose ranges (>200mg/dL and <65mg/dL) have a high specificity as predictors of death at discharge.
Type:
info:eu-repo/semantics/bachelorThesis
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Keywords:
Glucemia; Azúcar de la Sangre; Glucosa de la Sangre; Hospitalización; Preescolar

Full metadata record

DC FieldValue Language
dc.contributor.advisorSolari Zerpa, Lely Del Rosarioes
dc.contributor.advisorHernandez, Adrian V.es
dc.contributor.authorToro Polo, Luis Migueles
dc.contributor.authorOrtiz Lozada, Ricardo Yannickes
dc.contributor.authorChang Grozo, Silvana Luciaes
dc.date.accessioned2017-08-21T23:35:15Z-
dc.date.available2017-08-21T23:35:15Z-
dc.date.issued2016-02-08-
dc.identifier.urihttp://hdl.handle.net/10757/621830-
dc.description.abstractIntroduction. There is a high prevalence of mortality in the Pediatric Intensive Care Units (PICU) in developing countries. Association has been found between disglyce mia and mortality in the PICU; however, there is a lack of standardization of the utility of such ranges. Objectives. To analyze the association between glycemia levels in PICU admission and mortality in patients hospitalized at Instituto Nacional de Salud del Niño (INSN). Methods. Retrospective cohort in PICU patients admitted to INSN between 2012 and 2013. A Poisson regression model with robust variance was used to quantify the association. Diagnostic Test performance evaluation was used to describe sensitivit y, specificity, positive predictive value, negative predictive value and likelihood ratios for each range of glycemia. Results. 552 patients were included (Age range 5 to 79,8 months). The mean glycemia on admission was 121.3 mg/dL. Ninety two (16.6%) patients died during hospitalization. In multivariable analyses, significant associatio ns between glycemia <65 mg/dL (RR: 2.01, 95%CI 1.14-3.53), glycemia >200 mg/dL (RR: 2.91, 95%CI 1.71-4.55), malnutrition (RR: 1.53, 95%CI 1.04-2.25), mechanica l ventilation (RR: 3.71, 95%CI 1.17-11.76) and mortality at discharge were found. There was low sensitivity (between 17.39% and 39.13%) and high specificity (between 49.13% and 91.74%) for different glucose cut-off levels. Conclusions. There is an increased risk of death at discharge in patients who developed hypoglycemia and hyperglycemia on admission to the PICU. Certain glucose ranges (>200mg/dL and <65mg/dL) have a high specificity as predictors of death at discharge.es
dc.description.uriTesises_PE
dc.formatapplication/pdfes
dc.formatapplication/mswordes
dc.language.isoenges
dc.publisherUniversidad Peruana de Ciencias Aplicadas (UPC)es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subjectGlucemiaes_PE
dc.subjectAzúcar de la Sangrees_PE
dc.subjectGlucosa de la Sangrees_PE
dc.subjectHospitalizaciónes_PE
dc.subjectPreescolares_PE
dc.titleUtilidad de la glicemia a la admisión en la unidad de cuidados intensivos pediátrica como predictor de mortalidad de los pacientes hospitalizados en el Instituto Nacional de Salud del Niño, 2012-2013es
dc.typeinfo:eu-repo/semantics/bachelorThesises
thesis.degree.grantorUniversidad Peruana de Ciencias Aplicadas (UPC). Facultad de Ciencias de la Saludes_PE
thesis.degree.levelLicenciaturaes_PE
thesis.degree.disciplineMedicinaes_PE
thesis.degree.nameMédico cirujanoes_PE
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