Prevalencia y factores asociados a infección por Bordetella Pertussis en niños menores de 5 años con infección respiratoria aguda (IRA) en un hospital de Lima

2.50
Hdl Handle:
http://hdl.handle.net/10757/621806
Title:
Prevalencia y factores asociados a infección por Bordetella Pertussis en niños menores de 5 años con infección respiratoria aguda (IRA) en un hospital de Lima
Authors:
Pavic-Espinoza, Ivana; Bendezú Medina, Sandy; Herrera Alzamora, Angella
Advisors:
Del Valle Mendoza, Juana Mercedes ( 0000-0002-6011-5040 )
Publisher:
Universidad Peruana de Ciencias Aplicadas (UPC)
Issue Date:
25-Jan-2016
URI:
http://hdl.handle.net/10757/621806
Abstract:
Background: Pertussis diagnosis may go unrecognized when other pathogens, such as respiratory syncytial virus (RSV) circulate. Methods: A prospective cross-sectional study was conducted in Lima, Peru from January 2009 to September 2010. A total of 596 children under 5 years old admitted with clinical diagnoses of acute respiratory infections were test for B. pertussis and RSV detection by polymerase chain reaction (PCR). Results: The pertussis toxin and IS481 genes were detected in 19.12% (114/596) of the cases and the respiratory syncytial viruses (RSV-A and RSV-B) were identified in 17.28% (103/596) of patients. Infants under 3 months old were the most frequently affected by this pathogens in 43% (49/114) and 35.9% (37/103) respectively. An increase of B. pertussis was observed from February to March and from October to November with a Seasonal index between 1.32-1.51 and 1.24-3.5 respectively. Conclusions: Epidemiologic surveillance for B. pertussis is essential in Peru, especially in children that could most benefit from the vaccine. B. pertussis should be suspected in infants hospitalized for acute respiratory symptoms for early treatment and prevent complications.
Type:
info:eu-repo/semantics/bachelorThesis
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Keywords:
Bronchiolitis; Bordetella pertussis; Infants; Vaccine

Full metadata record

DC FieldValue Language
dc.contributor.advisorDel Valle Mendoza, Juana Mercedeses
dc.contributor.authorPavic-Espinoza, Ivanaes
dc.contributor.authorBendezú Medina, Sandyes
dc.contributor.authorHerrera Alzamora, Angellaes
dc.date.accessioned2017-08-21T16:10:15Z-
dc.date.available2017-08-21T16:10:15Z-
dc.date.issued2016-01-25-
dc.identifier.urihttp://hdl.handle.net/10757/621806-
dc.description.abstractBackground: Pertussis diagnosis may go unrecognized when other pathogens, such as respiratory syncytial virus (RSV) circulate. Methods: A prospective cross-sectional study was conducted in Lima, Peru from January 2009 to September 2010. A total of 596 children under 5 years old admitted with clinical diagnoses of acute respiratory infections were test for B. pertussis and RSV detection by polymerase chain reaction (PCR). Results: The pertussis toxin and IS481 genes were detected in 19.12% (114/596) of the cases and the respiratory syncytial viruses (RSV-A and RSV-B) were identified in 17.28% (103/596) of patients. Infants under 3 months old were the most frequently affected by this pathogens in 43% (49/114) and 35.9% (37/103) respectively. An increase of B. pertussis was observed from February to March and from October to November with a Seasonal index between 1.32-1.51 and 1.24-3.5 respectively. Conclusions: Epidemiologic surveillance for B. pertussis is essential in Peru, especially in children that could most benefit from the vaccine. B. pertussis should be suspected in infants hospitalized for acute respiratory symptoms for early treatment and prevent complications.es
dc.description.uriTesises_PE
dc.formatapplication/pdfes
dc.formatapplication/mswordes
dc.language.isoenges
dc.publisherUniversidad Peruana de Ciencias Aplicadas (UPC)es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subjectBronchiolitises
dc.subjectBordetella pertussises
dc.subjectInfantses
dc.subjectVaccinees
dc.titlePrevalencia y factores asociados a infección por Bordetella Pertussis en niños menores de 5 años con infección respiratoria aguda (IRA) en un hospital de Limaes
dc.typeinfo:eu-repo/semantics/bachelorThesises
thesis.degree.grantorUniversidad Peruana de Ciencias Aplicadas (UPC). Facultad de Ciencias de la Saludes_PE
thesis.degree.levelLicenciaturaes_PE
thesis.degree.disciplineMedicinaes_PE
thesis.degree.nameMédico cirujanoes_PE
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