Collections in this community

Recent Submissions

  • Impact of Virtuality and the Use of TIC by University Teachers in Times of the Covid 19 Pandemic

    Soto Carrión, Carolina; Jimenez Mendoza, Wilber; Jimenez Soto, Isabel Milagros (International Institute of Informatics and Cybernetics, 2023-01-01)
    The Covid19 pandemic has abruptly changed the way of teaching university teachers. Objective: to establish the impact of the change from face-to-face to virtuality in the teaching-learning process of university professors at the Technological University of the Andes, Abancay. Method: In the study, 151 teachers from the different careers and Faculties of the university participated, under a random shot. The intervening instrument has been a structured survey of 10 questions and a five-level scale and other closed ones sent by institutional emails, Results: The teachers of the Technological University of the Andes have not had any virtual means at the beginning of the pandemic and it was The change from face-to- face to virtuality had a great impact, with teachers who react quickly to the use of technologies (TIC) and some have been adapting with difficulty in subsequent months. Discussion: The university had difficulties at the beginning about the conditions and facilities for access to technological tools, connectivity, implementation, but there was a difficult but quick reaction from the teachers. Conclusions: University teachers after the start of the Covid19 pandemic, have adapted with many restrictions to the virtual modality, for having been a sudden, unexpected change Teachers have adopted virtual strategies with the use of Tic tools, accepting in a 41 % the Moodle system for the development of learning sessions at the University.
    Acceso restringido temporalmente
  • Student satisfaction in clinical area subjects during the COVID-19 pandemic in a medical school

    Diaz-Lazo, Anibal; Alvarez-Risco, Aldo; Córdova Rosales, Carlo; Cori Rosales, Sandra; Ruiz-Aquino, Mely; Del-Aguila-Arcentales, Shyla; Davies, Neal M.; Mejia, Christian R.; Yáñez, Jaime A. (Frontiers Media SA, 2023-01-01)
    Introduction: Coronavirus SARS-CoV-2 had an impact on health and education, among other subjects. It caused changes in teaching medicine. The objective of the study was to determine student satisfaction in the subjects of the clinical area in a medical school during the coronavirus SARS-CoV-2 pandemic. Methods: The current study has an observational, descriptive, and cross-sectional design. The sample consisted of 119 students. Inclusion criteria included being a student enrolled in the 2021–2022 semester, between the VI and XII semesters in a medical school. Results: It was found that the median age was 21 years; 68 (57.1%) were men. Overall student satisfaction was 67.1%. High student satisfaction was found in the dimension development of professional skills (84.9%), achievement of student expectations (69.7%), and virtual assistance (67.2%) at a medium level of student satisfaction. Flexibility in learning (64.7%), the use of infrastructure and facilities (61.7%), and the use of educational resources (61.3%) were reported. Discussion: The students were generally satisfied with the dynamic communication of the teachers, especially concerning promoting student participation (79%).
    Acceso abierto
  • Oral and general health conditions involved in periodontal status during pregnancy: a prospective cohort study

    Gil-Montoya, J. A.; Rivero-Blanco, T.; Leon-Rios, X.; Exposito-Ruiz, M.; Pérez-Castillo, I.; Aguilar-Cordero, M. J. (Springer Science and Business Media Deutschland GmbH, 2023-12-01)
    Purpose: Pregnancy is a period in a woman’s life that has important consequences on oral health, particularly for gingival health. Present study aims to identify women at higher risk of developing periodontal disease (gingivitis and periodontitis) during late pregnancy and evaluate how this condition evolves during this period. Methods: Prospective cohort study was designed with pregnant women who were assessed during the first and third trimesters of gestation in a southern Spanish public hospital. Data regarding gingival and periodontal health, oral hygiene, and overall health status (obesity and diabetes mellitus) were collected. Reporting followed STROBE checklist. Results: Significantly higher number of women had the periodontal and gingival disease in the third trimester of gestation compared with in early pregnancy. In the third trimester of gestation, 42 (28.6%) and 63 (42.9%) of women presented symptoms of periodontal disease and gingival disease, respectively. Obesity (OR 2.834; 95%CI 0.919–8.741), worse oral hygiene during the first trimester of gestation (OR: 4.031; 95%CI 2.12–7.65), and periodontal disease during early pregnancy (OR: 15.104; 95%CI 3.60–63.36) most effectively predicted periodontal disease during late pregnancy. Conclusions: Pregnancy is associated with exacerbated periodontal and gingival disease symptoms throughout the different trimesters of gestation. Obesity and oral hygiene during early pregnancy were the risk factors that most contributed to the aforementioned changes in periodontal disease.
    Acceso abierto
  • Clinical phenotypes of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19

    Alvarado-Gamarra, Giancarlo; Del Aguila, Olguita; Dominguez-Rojas, Jesús; Chonlon-Murillo, Kenny; Atamari-Anahui, Noé; Borcic, Aida; Sánchez, Sandra; Huamani-Echaccaya, Pablo; Garcés-Ghilardi, Raquel; Estupiñan-Vigil, Matilde (Sociedad Chilena de Pediatria, 2022-01-01)
    The multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C) is infre-quent but potentially lethal. There are few reports of this disease and its phenotypes in Latin America. Objective: To describe the characteristics of the clinical phenotypes of MIS-C in hospitalized patients in Lima, Peru. Patients and Method: A descriptive and retrospective study in patients under 14 years old with a diagnosis of MIS-C at the Hospital Nacional Edgardo Rebagliati Martins (Lima, Perú), from April 2020 to August 2021. Clinical-demographic and microbiological variables were recorded. According to these, patients with MIS-C were classified into the shock phenotype, Kawasaki disease (KD) without shock, and the fever and inflammation phenotype, analyzing their clinical outcomes. Results: 58 patients were analyzed. 32 (55.2%) presented the shock phenotype, 15 (25.8%) Kawasaki disease (KD) phenotype without shock, and 11 (19%) fever and inflammation phenotype. In the shock phenotype, 17 had KD. The mean age was 7 ± 3.5 years and 67.2% were males. Gastrointes-tinal and mucocutaneous manifestations predominated in all phenotypes. The mortality was 3.5%. The frequency of coronary aneurysms was 10.2%. Most patients received immunomodulatory and antiplatelet treatment. Patients with shock phenotype showed greater involvement in inflammatory markers, hematological dysfunction, and myocardial injury, with a higher frequency of respiratory failure and invasive mechanical ventilation. Conclusions: In our case series, patients with shock phenotype were the most frequent and had worse clinical outcomes. Active surveillance of clinical phenotypes is needed to make an early diagnosis and management to improve the prognosis in these patients.
    Acceso abierto
  • Cross-cultural measurement invariance of the purpose in life test - Short form (PIL-SF) in seven Latin American countries

    Caycho-Rodríguez, Tomás; Vilca, Lindsey W.; Cervigni, Mauricio; Gallegos, Miguel; Martino, Pablo; Calandra, Manuel; Anacona, Cesar Armando Rey; López-Calle, Claudio; Moreta-Herrera, Rodrigo; Chacón-Andrade, Edgardo René; Lobos-Rivera, Marlon Elías; del Carpio, Perla; Quintero, Yazmín; Robles, Erika; Lombardo, Macerlo Panza; Recalde, Olivia Gamarra; Figares, Andrés Buschiazzo; White, Michael; Videla, Carmen Burgos; Carbajal-León, Carlos (Springer, 2023-09-01)
    The aim was to test the cross-cultural measurement invariance of the PIL-SF in a sample of people from seven Latin American countries. Additionally, the characteristics of the PIL-SF items were evaluated and to assess the relationship between purpose in life, as measured by the PIL-SF, and fear of COVID-19. A total of 4306 people from seven Latin American countries participated in the study. The results indicated that the PIL-SF is invariant in the seven participating countries and, therefore, there is evidence that the items reflect the purpose of life in the same way in all countries. This allows comparisons of purpose in life between countries that are free of bias, reflecting the true differences in how countries respond to items. From IRT, the discrimination parameters are adequate and indicate that the items cover a wide range of the purpose in life construct. The difficulty parameters are adequate and increase monotonically. This indicates that people would need a higher level of purpose in life to respond to the higher response categories. Thus, the PIL-SF items would be useful in determining people with a relatively high degree of purpose in life. Identifying people with different levels of purpose in life would allow them to be part of intervention programs, either to support those with low levels or to maintain and reinforce their purpose in life. The evidence of cross-country measurement invariance of the PIL-SF provides a measure to be used in cross-cultural studies about the meaning of life.
    Acceso abierto
  • Evaluation of Solvent Efficacy of the Myrciaria Dubia (Camu-camu) Essential Oil in Root Canal Re-treatment Procedures: An In Vitro Study

    Wiess-Laurencio, Fabrizio A.; López-Rodriguez, Gabriela; Caballero-García, Stefany (aypee Brothers Medical Publishers (P) Ltd, 2022-01-01)
    Aim: To evaluate the solvent efficacy of an experimental substance based on the Myrciaria dubia (camu-camu) essential oil in root canal re-treatment procedures. Materials and methods: Sixty polylactic acid tubes (PLA) were used and divided into five groups (distilled water, M. dubia oil (camu-camu), xylene, orange peel, and eucalyptus oil). In each group, 12 tubes were filled with a temporary restorative material (Coltosol®). The upper and the middle part were filled with gutta-percha. A total of 0.1 mL solvent was added depending on the study group and left for 5 minutes. Once the solvent was placed, the samples were taken to the Instron 3382 machine. The force used to penetrate the spreader into the 5 mm depth was recorded in Newton (N). The Kruskal–Wallis test and Dunn’s post hoc test were used for multiple comparisons (p < 0.05). Statistical analysis was performed using Stata® v.15.0 package. Results: We found significant statistical differences when comparing all solvents (p = 0.001), obtaining 14.02 N for the experimental substance. The results of the superficial dissolution depth and the force used to penetrate the spreader to 5 mm revealed that the M. dubia oil (camu-camu) was the solvent that significantly softened the gutta-percha the most (p < 0.05). These values were followed by xylene and orange peel oil. We also found that the solvent with the lowest efficacy was eucalyptus oil. Conclusion: The M. dubia (camu-camu) essential oil had more softening power than other solutions in the study. Clinical significance: The efficacy of the M. dubia (camu-camu) essential oil is relevant as it is a nonharmful solvent that would not harm the periapical tissue and would reduce the time of endodontic re-treatments procedures, which is beneficial for patients.
  • Neural Network Strategies and Models for Voice Cloning in a Multi-speaker Mode: An Overview

    Fura-Mendoza, Marco; Moscol-Albañil, Isabel; Rodriguez, Ciro; Lezama, Pedro; Rodriguez, Diego; Pomachagua, Yuri (Springer Science and Business Media Deutschland GmbH, 2023-01-01)
    The evolution of data science and the constant challenge of carrying out different processes using a few resources with simultaneous personalization has promoted interest in the development of voice cloning. Nowadays, different machine learning techniques are used, given their efficiency in generating relationships across multiple parameters. In this regard, we evaluated the best-performing models and the different process optimization strategies within this sector, where through neural network models separated modularly by their functionality, it is possible to generate independent processes taking into account the most significant number of linguistic factors in the generation of the voice, thus obtaining significant results of a clear improvement in the whole process of synthesizing the voice of a target speaker.
    Acceso restringido temporalmente
  • How Current Chatbots Applications Impact Education: An Overview

    Yataco-Irrazábal, Saroff; Moscol-Albañil, Isabel; Rodriguez, Ciro; Lezama, Pedro; Rodriguez, Diego; Pomachagua, Yuri (Springer Science and Business Media Deutschland GmbH, 2023-01-01)
    The implementation of chatbots in multiple platforms with which man interacts has allowed automating processes and being able to respond to requests, one of its applications is the educational field, where they are still experimenting with good results in some areas and in others analyzing their feasibility, the deployment of this technology has been used both in basic education and in higher education, the former mainly addresses the resolution of simple queries facilitating the work of the teacher, and the latter seeks to go further by offering itself as a learning assistant. This work focuses on understanding the impact that chatbots have on education and their integration in some areas of the educational process, analyzing the results offered by other research and real applications. Chatbots have proved to be effective and increase user efficiency by providing information and being a support, evaluation, and follow-up tool. They have even shown favorable results in several learning levels, being a source that centralizes information without the need for the user to access multiple sources to learn a subject or to monitor the level of learning of students or their own.
    Acceso restringido temporalmente
  • Active case-finding for TB among incarcerated women in Peru

    Puma, D.; Geadas, C.; Calderon, R. I.; Yuen, C. M.; Jiménez, J.; Córdova, M.; Martínez, B.; Peinado, J.; Lecca, L.; Tovar, M.; Puma, Daniela (International Union Against Tuberculosis and Lung Disease, 2023-10-01)
    Carta al editor
    Acceso abierto
  • Deep Learning Algorithms in Chest Images for Pneumonia Detection

    Porras, Fernando Tello; Rodriguez, Ciro; Rodriguez, Diego; Lezama, Pedro; Inquilla, Ricardo; Pomachagua, Yuri (Institute of Electrical and Electronics Engineers Inc., 2022-01-01)
    neumonia has become the respiratory disease that continuously causes deaths in the world; as a response to this serious problem, a literature review is performed to identify Deep Learning classification models for pneumonia detection with an accuracy higher than 95%. For the identification of the models, different architectures such as InceptionV3, MobileNet, MobileNetV2 Xception, VGG16, VGG19, DenseNet201, NasnetMobile, CNN, and LSTM were evaluated. Although they all show very acceptable accuracy indicators, which justifies their evaluation for model identification, the datasets were evaluated with chest X-ray images in different categories. As a result, it was determined that ResNet152V2 achieved an accuracy of 99.22%, which is considered one of the best models for pneumonia detection.
    Acceso restringido temporalmente
  • Gyms Customer Loyalty Using the Logistic Regression Algorithm Technique

    Munoz, Joaquin Moreno; Osorio, Miguel Ramirez; Rodriguez, Ciro; Rodriguez, Diego; Lezama, Pedro; Pomachagua, Yuri (Institute of Electrical and Electronics Engineers Inc., 2022-01-01)
    The objective of this work is to implement the logistic regression technique in datasets of gyms to identify and make a respective analysis for a correct segmentation of clients and, in this way, maximize the possibility of retaining clients; this will also allow us to rule out wrong decisions and incorrect assumptions, in addition to optimizing management according to customer data, which will be vital for a correct loyalty of gym users. The precision calculated the loyalty by the logistic regression algorithm considering important factors such as the rate of abandonment.
    Acceso restringido temporalmente
  • Análisis de serie de tiempo de patrones estacionales en defunciones por neumonía en el Perú, periodo 2003-2017

    Sánchez, Carlos A.; Davila, Cristina; Laura, Wil; Maguiña, Ciro (Universidad Nacional Mayor de San Marcos, Facultad de Medicina, 2022-01-01)
    Introduction. It is generally accepted that respiratory infections are seasonal, but high-frequency periods are rarely identified at the local level in a country with diverse climates. Anticipating the pneumonia season locally can provide a better use of critical resources. Objective. The aim of the study was to examine seasonal variability in monthly deaths due to pneumonia in Peru. Methods. Observational retrospective study using time series analysis to identify periods of high pneumonia mortality in seven cities in Peru. We reviewed administrative reports from the Ministry of Health for pneumonia deaths during 2003-2017. Descriptive statistics were calculated and a time series analysis at a monthly scale was performed on the frequency of deaths due to pneumonia, cumulative rainfall, and maximum and minimum environmental temperatures. Results: 94.4% of pneumonia deaths (N = 166,844) were reported as pneumonia due to “unspecified organism”, and 75.6% were adults older than 65 years. In the cities of Tarma, Arequipa and Cusco, minimum ambient temperature is negatively correlated to pneumonia deaths in all age groups and at least one risk group. In Iquitos, minimum temperature is positively correlated with deaths among children under 5 years of age. The cities of Pucallpa and Cajamarca reported no statistically significant correlation. The climate in Lima is a peculiar case. The distribution of pneumonia deaths throughout the year suggests a north-south sequence, while the climate space-time analysis suggests a south-north pattern. Conclusion: Results show different seasonal patterns for pneumonia deaths in different cities and risk groups.
    Acceso abierto
  • Telehealth Outpatient Monitoring of a SARS-CoV-2 Familial Cluster Infection in Peru: Adapting to a Healthcare Crisis

    Arriola-Montenegro, José; Arriola-Montenegro, Liliana; Beas, Renato; Díaz-Pardavé, Celeste (University of the Philippines Manila, 2022-01-01)
    The coronavirus disease 2019 (COVID-19) epidemic is evolving in Latin America despite implementation of government measures. We report a familial cluster in Lima, Peru, with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Two young and two middle-aged adults with a wide range of COVID-19 manifestations experienced successful management under telehealth outpatient monitoring. Telehealth monitoring was scheduled as suggested by Peruvian Ministry of Health Guidelines and was performed by a designated physician who assessed the patients and prescribed treatment. On May 14, 2020, a 25-year-old male, who worked treating COVID-19 patients, reported constitutional symptoms and tested positive for SARS-CoV-2. Clinical improvement was achieved with azithromycin and ivermectin therapy. He had been in contact with his parents (Cases 2 and 3) and his sister (Case 4). Cases 2 and 3 developed moderate pulmonary compromise requiring oxygen supplementation and pharmacological therapy, including corticosteroids and anticoagulation, under home medical assessment and telehealth monitoring. Case 4 developed mild symptoms and periorbital rash, an atypical dermatological finding. To our knowledge this represents the first report of a familial cluster with COVID-19 that was successfully managed under scheduled telehealth outpatient monitoring in Latin America.
    Acceso abierto
  • Experiencias de maternidad en mujeres peruanas adultas que fueron madres en su adolescencia

    del Carmen Robles-Esparza, Andrea; Barboza-Palomino, Miguel (Ediciones Mayo S.A., 2022-01-01)
    Acceso abierto
  • Association between caregiver burden and the presence of neurological alterations in a Peruvian geriatric population

    Leiva-Socualaya, Steven Joseph; Guerra-Ramirez, Lisbeth Nohelia; Carreazo, Nilton Yhuri (Spanish Publishers Associate, 2023-01-01)
    Objective: The objective of this study is to establish the association between caring for older adults with neurological disorders and suffering from caregiver burden at the Naval Geriatric Center of Peru, from November 2019 to January 2021. Methodology: Analytical, observational, cross-sectional study carried out at the Geriatric Center of the Naval Medical Center. A total of 290 older adult's caregivers who went to medical consultation were surveyed. Caregiver burden was measured with the Zarit burden scale. Results: A prevalence of caregiver burden of 52.76% was found. The patients that suffered some neurological alteration were 62.76%. When adjusting for sociodemographic variables, being the patient's spouse increased the probability of suffering from caregiver burden by 2.23 times. When adjusting for the variables related to care, caring for a patient with neurological disorder and caring for an older adult for 1 or 2 years increased the probability of suffering caregiver burden by 1.86 and 1.91 times, respectively, while having the support of other people decreased the probability of suffering it by 39%. Conclusions: Caregiver overload is associated with caring for an older adult with neurological disorder, being the patient's spouse, caring for 1 or 2 years and having the support of other people.
    Acceso abierto
  • Peruvian scientific production on antimicrobial-resistant bacteria prioritized by WHO

    Sandoval, Kenyo D.; Deza-Santos, Flor; Pinedo-Castillo, Liseth; Mateo-Pacora, Jimmy; Rondan, Paola L.; Alcedo, Sami; Taype-Rondan, Álvaro (Editorial Ciencias Medicas, 2023-01-01)
    Introduction: Antimicrobial resistance (AMR) is a worldwide public health crisis. The World Health Organization (WHO) established a priority list of resistant bacteria to guide research and alternatives for improvement. Objective: To describe the scientific production of Peru on AMR of bacteria prioritized by the World Health Organization, between 2012 and 2021. Methods: Observational descriptive study of bibliometric type in journals indexed in Scopus during the period 2012-2021. The selection of studies and data extraction were performed manually in duplicate. Resistant bacteria studied were classified based on priority (critical, high, and medium). Results: A total of 118 articles were included. During the period 2014-2021, the number of publications increased. The articles published in English accounted for 61.9%, 98.3% had their affiliation in Peru, and 77.1% were conducted in Lima. Most publications focused on bacteria of critical priority than high and medium priority. A total of 79.7% sought to determine prevalence or characterize and 26.1% referred to funding from Peruvian institutions. Conclusions: Peruvian scientific production on AMR has increased in recent years and there are more publications on critical priority bacteria. However, these studies are centered in Lima and only a quarter of them have been financed by a Peruvian entity.
    Acceso abierto
  • Effects of vaccination against COVID-19 on the emotional health of older adults

    Alarcon-Ruiz, Christoper A.; Romero-Albino, Zoila; Soto-Becerra, Percy; Huarcaya-Victoria, Jeff; Runzer-Colmenares, Fernando M.; Romani-Huacani, Elisa; Villarreal-Zegarra, David; Maguiña, Jorge L.; Apolaya-Segura, Moises; Cuba-Fuentes, Sofía (F1000 Research Ltd, 2022-01-01)
    Background: The COVID-19 pandemic significantly impacted the mental and emotional health of the elderly, especially those from low to middle-income countries. However, COVID-19 vaccination may reduce this influence. Therefore, we aimed to estimate the effect of vaccination against COVID-19 on the emotional health of older adults. Methods: We selected a national, random, and stratified sample of non-hospitalized adults aged 60 to 79 years from Peru who intended to receive or had already received the COVID-19 vaccine during recruitment. During June and July 2021, the assessed outcomes were the fear, anxiety, and worry about COVID-19, general anxiety, and depression at baseline and after a month. We estimated the adjusted odds ratios (aOR) and 95% confidence intervals (95% CI) for each altered emotional health outcomes in those who had one and two doses, compared with those who were not vaccinated using multilevel logistic regression with mixed effects. Results: We recruited 861 older adults with 20.8% of loss to follow-up. At baseline, 43.9% had received only one dose of the vaccine, and 49.1% had two doses. In the analysis during follow-up, those who had two doses had less fear (aOR: 0.19; CI 95%: 0.07 to 0.51) and anxiety to COVID-19 (aOR: 0.45; CI 95%: 0.22 to 0.89), compared to unvaccinated. We observed no effects in those with only one dose. Conclusions: Two doses of COVID-19 vaccination in older adults improves their perception of COVID-19 infection consequences. This information could be integrated into the vaccination campaign as an additional beneficial effect.
    Acceso abierto
  • The role of university teachears facing academic dishonesty from their students

    Cayo-Rojas, César Félix; Paucar-Rodríguez, Elizabeth; Miranda-Dávila, Ana Sofía (Centro Nacional de Informacion de Ciencias Medicas, 2022-03-26)
    Acceso abierto
  • Acute presentation of post-traumatic stress by COVID-19

    Reyes-Tejada, Alejandra L.; Gonzales-Huaman, Keysi S.; Leon-Nina, Estefania C.; Murga-Cabrera, Anne E.; Carrasco-Altamirano, Jhosimar A.; Mejia, Christian R. (Editorial Ciencias Medicas, 2022-04-01)
    Introduction: COVID-19 has generated diverse reactions and social changes in different populations, which may influence mental health. Objective: To describe the characteristics and risk factors of post-traumatic stress by COVID-19 in the Peruvian population. Methods: A retrospective cohort was studied in 2276 people over 18 years of age. The diagnosis of post-traumatic stress disorder was obtained with the Short Post-traumatic Stress Disorder Rating Interview (SPRINT-E) scale (α = 0.92), which was crossed with important variables; association statistics were obtained. Results: The main risk factors for post-traumatic stress were being a woman (p < 0.001); having obesity or cardiovascular disease (p < 0.001); spending more hours per day being informed about the subject (p< 0.001); having a family member who had suffered from post-traumatic stress disorder (p < 0.001); having a relative who has suffered from COVID-19 (p = 0.045), having a relative or friend who has died from this disease (p = 0.020); having relatives with psychiatric diagnoses (p = 0.018); having a harmful habit (p < 0.001), suffering from depression, anxiety or stress (p < 0.001; for each of the three disorders). On the contrary, the older the age (p<0.001) and the higher the academic degree (p<0.001), the lower the risk of post-traumatic stress. Conclusion: The factors associated with post-traumatic stress due to COVID-19 in the Peruvian population are obesity or cardiovascular disease, possession of harmful habits, family psychiatric history, having family members infected or killed by COVID-19, and suffering from depression, anxiety or stress.
    Acceso abierto
  • RISK FACTORS FOR INTENSIVE CARE UNIT ADMISSION OR MORTALITY IN ADULTS HOSPITALIZED FOR COVID-19 AT HIGH ALTITUDE

    Alva, Niza; Asqui, Giovana; Alvarado, Germán F.; Muchica, Francisco (Instituto Nacional de Salud, 2022-04-01)
    Objective. To determine the risk factors for admission to the intensive care unit (ICU) or mortality in patients hospitalized for COVID-19 in a hospital in Puno, Peru. Materials and methods. Retrospective cohort study in adults hospitalized between April and December 2020. We evaluated Sociodemographic characteristics, vital functions, comorbidities, treatment received and its association with admission to ICU or mortality (adverse outcome). Poisson regression with robust variance was used to calculate crude and adjusted relative risks (RR) with their 95% confidence intervals (95%CI). Results. A total of 348 medical records were analyzed. The median age in years was 42.5 (IQR: 30.0; 58.0); 38.2% were male, and 35.3% died or were admitted to the ICU. Those admitted with an oxygen saturation ≤ 75% were 2.79 times more likely to have the adverse outcome (p < 0.001), compared to those admitted with a saturation ≥ 85%; those admitted with a value between 75-79% were 2.92 times more likely to have the adverse outcome (p < 0.001); likewise, those admitted with saturation between 80-84% were 1.70 times more likely to have the adverse outcome; however, the difference was not statistically significant (p=0.066). In addition, male patients, RR= 1.75 (p<0.001); those aged > 40 years, RR 3.5 (p=0.001); those with tachypnea, RR=1.66 (p=0.010); or with diabetes, RR = 1.53 (p=0.011) had higher risk of presenting the adverse outcome. Conclusions. The risk factors for ICU admission or mortality due to COVID-19 were male sex, age over 40 years, low saturation, diabetes and tachypnea.
    Acceso abierto

View more