2.50
Hdl Handle:
http://hdl.handle.net/10757/614830
Title:
Tumor de Leydig simulando una neoplasia germinal
Other Titles:
Leydig tumour simulating a germ cell neoplasm
Authors:
Gamboa Acuña, Brenda Adriana; Guillén Zambranoa, Rayza; Lizzetti Mendozaa, Grecia
Citation:
Gamboa-acu B, Guillén-zambrano R, Lizzetti-mendoza G. Tumor de Leydig simulando una neoplasia germinal. 2016;(xx).
Publisher:
Elsevier B.V.
Journal:
Gaceta Mexicana de Oncología
Issue Date:
22-Jun-2016
URI:
http://hdl.handle.net/10757/614830
Additional Links:
http://www.sciencedirect.com/science/article/pii/S1665920116300335
Abstract:
Main findings A case is presented of a Leydig cell neoplasm in a 25 year-old male patient with no classic risk factors with an atypical outcome. The tumour mass was histologically analysed and was found to have features compatible with a germ cell neoplasm. A right orchiectomy was performed, followed by chemotherapy. After treatment, pulmonary metastasis, lymph nodes, and peri-hepatic hydronephrosis were found. The patient died two months after his last hospital admission. Case hypothesis Leydig cell tumours account for 1% to 3% of all testicular tumours. They occur at any age, especially in children, and between the third and sixth decade of life. Around 90% are benign, and 10% are malignant; these latter usually occurring between 50 and 60 years old, and are associated with sizes larger than 5 cm and gynecomastia. Finally, it is difficult to predict the development of the disease based on histopathological observations. Promising future implications Although non-germ cell tumours are rare, it is important to consider them in the differential diagnosis of testicular tumours, particularly in those of non-seminoma origin. Immunohistochemistry is useful for the differentiation of testicular tumours in those cases when conventional histology shows no conclusive findings.
Abstract:
Hallazgos principales Reportamos un caso de neoplasia de células de Leydig en un paciente varón de 25 años, sin factores de riesgo clásicos con evolución tórpida. Se analizó la histopatología de la masa tumoral y se encontró malignidad por lo que se decide realizar orquiectomía derecha, seguida de quimioterapia. Luego del tratamiento se halla metástasis pulmonar, adenopatías perihepáticas e hidronefrosis, falleciendo 2 meses después de su último ingreso hospitalario. Hipótesis del caso El tumor de células de Leydig representa entre el 1-3% de todos los tumores testiculares. Se presentan a cualquier edad; sobre todo en la infancia y en la 3.a-6.a década de la vida. Aproximadamente el 90% son de curso benigno y el 10% son malignos, presentándose sobre todo entre la 5.a y la 6.a década de la vida, y están asociados con un tamaño > 5 cm y ginecomastia. Finalmente, es difícil predecir el comportamiento en términos histológicos. Repercusiones a futuro A pesar que los tumores de células no germinales son poco frecuentes, es importante considerarlos como diagnóstico para brindar el tratamiento óptimo y evitar resultados desafortunados.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
spa
Keywords:
Células de Leydig; Tumor testicular; Inmunohistoquímica; Ginecomastia; Immunohistochemistry; Gynecomastia
ISSN:
1665-9201
Email:
glizzetti@gmail.com

Full metadata record

DC FieldValue Language
dc.contributor.authorGamboa Acuña, Brenda Adrianaes_PE
dc.contributor.authorGuillén Zambranoa, Rayzaes_PE
dc.contributor.authorLizzetti Mendozaa, Greciaes_PE
dc.date.accessioned2016-06-27T14:55:06Z-
dc.date.available2016-06-27T14:55:06Z-
dc.date.issued2016-06-22-
dc.identifier.citationGamboa-acu B, Guillén-zambrano R, Lizzetti-mendoza G. Tumor de Leydig simulando una neoplasia germinal. 2016;(xx).es_PE
dc.identifier.issn1665-9201-
dc.identifier.urihttp://hdl.handle.net/10757/614830es_PE
dc.description.abstractMain findings A case is presented of a Leydig cell neoplasm in a 25 year-old male patient with no classic risk factors with an atypical outcome. The tumour mass was histologically analysed and was found to have features compatible with a germ cell neoplasm. A right orchiectomy was performed, followed by chemotherapy. After treatment, pulmonary metastasis, lymph nodes, and peri-hepatic hydronephrosis were found. The patient died two months after his last hospital admission. Case hypothesis Leydig cell tumours account for 1% to 3% of all testicular tumours. They occur at any age, especially in children, and between the third and sixth decade of life. Around 90% are benign, and 10% are malignant; these latter usually occurring between 50 and 60 years old, and are associated with sizes larger than 5 cm and gynecomastia. Finally, it is difficult to predict the development of the disease based on histopathological observations. Promising future implications Although non-germ cell tumours are rare, it is important to consider them in the differential diagnosis of testicular tumours, particularly in those of non-seminoma origin. Immunohistochemistry is useful for the differentiation of testicular tumours in those cases when conventional histology shows no conclusive findings.-
dc.description.abstractHallazgos principales Reportamos un caso de neoplasia de células de Leydig en un paciente varón de 25 años, sin factores de riesgo clásicos con evolución tórpida. Se analizó la histopatología de la masa tumoral y se encontró malignidad por lo que se decide realizar orquiectomía derecha, seguida de quimioterapia. Luego del tratamiento se halla metástasis pulmonar, adenopatías perihepáticas e hidronefrosis, falleciendo 2 meses después de su último ingreso hospitalario. Hipótesis del caso El tumor de células de Leydig representa entre el 1-3% de todos los tumores testiculares. Se presentan a cualquier edad; sobre todo en la infancia y en la 3.a-6.a década de la vida. Aproximadamente el 90% son de curso benigno y el 10% son malignos, presentándose sobre todo entre la 5.a y la 6.a década de la vida, y están asociados con un tamaño > 5 cm y ginecomastia. Finalmente, es difícil predecir el comportamiento en términos histológicos. Repercusiones a futuro A pesar que los tumores de células no germinales son poco frecuentes, es importante considerarlos como diagnóstico para brindar el tratamiento óptimo y evitar resultados desafortunados.es_PE
dc.formatapplication/pdfes_PE
dc.formatapplication/htmles_PE
dc.language.isospaes_PE
dc.publisherElsevier B.V.es_PE
dc.relation.urlhttp://www.sciencedirect.com/science/article/pii/S1665920116300335es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subjectCélulas de Leydiges_PE
dc.subjectTumor testiculares_PE
dc.subjectInmunohistoquímicaes_PE
dc.subjectGinecomastiaes_PE
dc.subjectImmunohistochemistryes_PE
dc.subjectGynecomastiaes_PE
dc.titleTumor de Leydig simulando una neoplasia germinales_PE
dc.title.alternativeLeydig tumour simulating a germ cell neoplasmes_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.journalGaceta Mexicana de Oncologíaes_PE
dc.description.peer-reviewRevisión por pareses_PE
dc.contributor.emailglizzetti@gmail.comes_PE
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