Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms

2.50
Hdl Handle:
http://hdl.handle.net/10757/554305
Title:
Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms
Authors:
Pons, Maria J.; Gomes, Cl觃udia; Bada, Carlos; Reyes, Isabel; Del Valle Mendoza, Juana; Ruiz, Joaquim
Publisher:
Elsevier B.V.
Journal:
Asian Pacific Journal of Tropical Medicine (Asian Pacific Journal of Tropical Medicine)
Issue Date:
20-May-2015
URI:
http://hdl.handle.net/10757/554305
DOI:
10.1016/S1995-7645(14)60361-8
Additional Links:
https://www.researchgate.net/publication/276831508_Characterization_of_two_Achromobacter_xyloxosidans_isolates_from_patients_with_pertussis-like_symptoms
Abstract:
Objective: To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance program. Methods: Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and PCR. Results: Two Achromobacter xylosoxidans A8, closely related to Bordetella spp. were recovered from 2 patients diagnosed of pertussis, both carrying the ptxA gene and IS418 the pertussis toxin encoding gene. Subsequently, antibiotic susceptibility was evaluated by disk-diffusion method and by PCR. Conclusions: Although more detailed studies are needed, the present data highlight the possibility that Achromobacter xylosoxidans, closely related Bordetella pertussis microorganisms and not covered under the vaccine umbrella, might also result in cases of whooping cough. Thereby further surveillance is necessary to determine the extension and relevance of their pathogenic role in order to discriminate their real public health implication.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Description:
joruiz@clinic.ub.es
Keywords:
Achromobacter xylosoxidans; Bordetella pertussis
ISSN:
1995-7645

Full metadata record

DC FieldValue Language
dc.contributor.authorPons, Maria J.es_PE
dc.contributor.authorGomes, Cl觃udiaes_PE
dc.contributor.authorBada, Carloses_PE
dc.contributor.authorReyes, Isabeles_PE
dc.contributor.authorDel Valle Mendoza, Juanaes_PE
dc.contributor.authorRuiz, Joaquimes_PE
dc.date.accessioned2015-05-20T15:21:00Zes_PE
dc.date.available2015-05-20T15:21:00Zes_PE
dc.date.issued2015-05-20es_PE
dc.identifier.issn1995-7645es_PE
dc.identifier.doi10.1016/S1995-7645(14)60361-8es_PE
dc.identifier.urihttp://hdl.handle.net/10757/554305es_PE
dc.descriptionjoruiz@clinic.ub.eses_PE
dc.description.abstractObjective: To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance program. Methods: Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and PCR. Results: Two Achromobacter xylosoxidans A8, closely related to Bordetella spp. were recovered from 2 patients diagnosed of pertussis, both carrying the ptxA gene and IS418 the pertussis toxin encoding gene. Subsequently, antibiotic susceptibility was evaluated by disk-diffusion method and by PCR. Conclusions: Although more detailed studies are needed, the present data highlight the possibility that Achromobacter xylosoxidans, closely related Bordetella pertussis microorganisms and not covered under the vaccine umbrella, might also result in cases of whooping cough. Thereby further surveillance is necessary to determine the extension and relevance of their pathogenic role in order to discriminate their real public health implication.eng
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherElsevier B.V.es_PE
dc.relation.urlhttps://www.researchgate.net/publication/276831508_Characterization_of_two_Achromobacter_xyloxosidans_isolates_from_patients_with_pertussis-like_symptomses_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subjectAchromobacter xylosoxidanses_PE
dc.subjectBordetella pertussises_PE
dc.titleCharacterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptomses_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.journalAsian Pacific Journal of Tropical Medicine (Asian Pacific Journal of Tropical Medicine)es_PE
dc.description.fundingThis work has been supported by Sanofi Aventis del Peru. JR has a fellowship from the program I3, of the ISCIII (grant number: CES11/012), CG has a PhD fellowship of the ISCIII (FI12/00561). MJP has a fellowship from CONCYTEC/FONDECYT.es_PE
dc.description.peer-reviewRevisión por pareses_PE
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