Diagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Women

2.50
Hdl Handle:
http://hdl.handle.net/10757/552241
Title:
Diagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Women
Authors:
Qiu-Yue, Zhong; Gelaye, Bizu; Zaslavsky, Alan M.; Fann, Jesse R.; Rondon, Marta B.; Sánchez, Sixto E.; Williams, Michelle A.
Citation:
Zhong Q-Y, Gelaye B, Zaslavsky AM, Fann JR, Rondon MB, et al. (2015) Diagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Women. PLoS ONE 10(4): e0125096. doi:10.1371/journal.pone.0125096
Publisher:
PLoS ONE
Journal:
PLoS ONE
Issue Date:
4-May-2015
URI:
http://hdl.handle.net/10757/552241
DOI:
10.1371/journal.pone.0125096
Additional Links:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125096
Abstract:
OBJECTIVE: Generalized anxiety disorder (GAD) during pregnancy is associated with several adverse maternal and perinatal outcomes. A reliable and valid screening tool for GAD should lead to earlier detection and treatment. Among pregnant Peruvian women, a brief screening tool, the GAD-7, has not been validated. This study aims to evaluate the reliability and validity of the GAD-7. METHODS: Of 2,978 women who attended their first perinatal care visit and had the GAD-7 screening, 946 had a Composite International Diagnostic Interview (CIDI). The Cronbach's alpha was calculated to examine the reliability. We assessed the criterion validity by calculating operating characteristics. The construct validity was evaluated using factor analysis and association with health status on the CIDI. The cross-cultural validity was explored using the Rasch Rating Scale Model (RSM). RESULTS: The reliability of the GAD-7 was good (Cronbach's alpha = 0.89). A cutoff score of 7 or higher, maximizing the Youden Index, yielded a sensitivity of 73.3% and a specificity of 67.3%. One-factor structure of the GAD-7 was confirmed by exploratory and confirmatory factor analysis. Concurrent validity was supported by the evidence that higher GAD-7 scores were associated with poor self-rated physical and mental health. The Rasch RSM further confirmed the cross-cultural validity of the GAD-7. CONCLUSION: The results suggest that the Spanish-language version of the GAD-7 may be used as a screening tool for pregnant Peruvian women. The GAD-7 has good reliability, factorial validity, and concurrent validity. The optimal cutoff score obtained by maximizing the Youden Index should be considered cautiously; women who screened positive may require further investigation to confirm GAD diagnosis.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
en
Keywords:
Diagnostic medicine; Factor analysis; Anxiety disorders; Mental health and psychiatry; Social discrimination; Anxiety; Cross-cultural studies; Relaxation (psychology
EISSN:
1932-6203

Full metadata record

DC FieldValue Language
dc.contributor.authorQiu-Yue, Zhonges_PE
dc.contributor.authorGelaye, Bizues_PE
dc.contributor.authorZaslavsky, Alan M.es_PE
dc.contributor.authorFann, Jesse R.es_PE
dc.contributor.authorRondon, Marta B.es_PE
dc.contributor.authorSánchez, Sixto E.es_PE
dc.contributor.authorWilliams, Michelle A.es_PE
dc.date.accessioned2015-05-04T20:00:21Zes_PE
dc.date.available2015-05-04T20:00:21Zes_PE
dc.date.issued2015-05-04es_PE
dc.identifier.citationZhong Q-Y, Gelaye B, Zaslavsky AM, Fann JR, Rondon MB, et al. (2015) Diagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Women. PLoS ONE 10(4): e0125096. doi:10.1371/journal.pone.0125096es_PE
dc.identifier.doi10.1371/journal.pone.0125096es_PE
dc.identifier.urihttp://hdl.handle.net/10757/552241es_PE
dc.description.abstractOBJECTIVE: Generalized anxiety disorder (GAD) during pregnancy is associated with several adverse maternal and perinatal outcomes. A reliable and valid screening tool for GAD should lead to earlier detection and treatment. Among pregnant Peruvian women, a brief screening tool, the GAD-7, has not been validated. This study aims to evaluate the reliability and validity of the GAD-7. METHODS: Of 2,978 women who attended their first perinatal care visit and had the GAD-7 screening, 946 had a Composite International Diagnostic Interview (CIDI). The Cronbach's alpha was calculated to examine the reliability. We assessed the criterion validity by calculating operating characteristics. The construct validity was evaluated using factor analysis and association with health status on the CIDI. The cross-cultural validity was explored using the Rasch Rating Scale Model (RSM). RESULTS: The reliability of the GAD-7 was good (Cronbach's alpha = 0.89). A cutoff score of 7 or higher, maximizing the Youden Index, yielded a sensitivity of 73.3% and a specificity of 67.3%. One-factor structure of the GAD-7 was confirmed by exploratory and confirmatory factor analysis. Concurrent validity was supported by the evidence that higher GAD-7 scores were associated with poor self-rated physical and mental health. The Rasch RSM further confirmed the cross-cultural validity of the GAD-7. CONCLUSION: The results suggest that the Spanish-language version of the GAD-7 may be used as a screening tool for pregnant Peruvian women. The GAD-7 has good reliability, factorial validity, and concurrent validity. The optimal cutoff score obtained by maximizing the Youden Index should be considered cautiously; women who screened positive may require further investigation to confirm GAD diagnosis.eng
dc.formatapplication/pdfes_PE
dc.language.isoenes_PE
dc.publisherPLoS ONEes_PE
dc.relation.urlhttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125096es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subjectDiagnostic medicinees_PE
dc.subjectFactor analysises_PE
dc.subjectAnxiety disorderses_PE
dc.subjectMental health and psychiatryes_PE
dc.subjectSocial discriminationes_PE
dc.subjectAnxietyes_PE
dc.subjectCross-cultural studieses_PE
dc.subjectRelaxation (psychologyes_PE
dc.titleDiagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Womenes_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.eissn1932-6203es_PE
dc.identifier.journalPLoS ONEes_PE
dc.description.funding: This research was supported by an award from the Eunice Kennedy Shriver Institute of Child Health and Human Development (R01-HD-059835) at the National Institutes of Health (NIH). The NIH had no further role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the paper for publicationeng
dc.description.peer-reviewRevisión por pareses_PE
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