Assessment with liver function tests and hydroperoxides in short term very-lowbirth-weight neonatal parenteral nutrition

2.50
Hdl Handle:
http://hdl.handle.net/10757/347040
Title:
Assessment with liver function tests and hydroperoxides in short term very-lowbirth-weight neonatal parenteral nutrition
Authors:
Ferreyra, M.E.; Ocaña, M.C.; Bullón, E.N.
Citation:
Ferreyra ME, Ocaha MC, Bullôn EN. Lb003-Mon Assessment With Liver Function Tests and Hydroperoxides in Short-Term Very-Low-Birth-Weight Neonatal Parenteral Nutrition. Clin Nutr Suppl [Internet]. 2011;6(1):216. Available from: http://hdl.handle.net/10757/347040
Publisher:
Elsevier B.V.
Journal:
Clinical Nutrition Supplements
Issue Date:
23-Mar-2015
URI:
http://hdl.handle.net/10757/347040
Additional Links:
http://www.sciencedirect.com/science/journal/17441161/6/1
Abstract:
Rationale: It has been reported that PN (parenteral nutrition) in preterm neonates may have deleterious effects on hepatic function. We also studied the influence of peroxidation in PN bags, with and without light protection. Methods: 30 neonates weighing 1000 1500 g on TPN were studied prospectively. Serum samples were taken at start and at end of PN. Peroxides from 31 bags at 0, 5, 18 and 24 hours were measured. PN samples were taken from both light protected and not light protected PN bags. Results: Patients: (1) With PN: GOT = 28.63±13.00 IU; GPT = 7.37±5.10 IU; TB = 9.03±3.40 IU; DB = 0.845 ±0.43 UI; GGT = 110.41±81.87 IU. (2) Without PN: GOT = 28.73±16.36 IU; GPT = 10.53±8.38 IU; TB = 6.36±3.91 IU; DB = 1.35±1.53 IU; GGT = 128.38±75.74 IU. Significant differences: GPT, TB and DB (p < 0.05). Peroxides in bags: light protected and not, respectively, at 0 hours: 278.01±139.92 and 299.87±166.00, at 5 hours: 142.28±117.93 and 155.11±140.81, at 18 hours 183.39±115.40 and 212.92±133.72 and at 24 hours 258.58±187.81 and 284.55±162.78. At 18 hours the difference was significant (p < 0.05). Conclusions: 1. TB and 18-hour hydroperoxides concentrations were higher in serum, with PN and in light unprotected PN bags, respectively. 2. GPT and DB serum levels were lower with PN. 3. Within the conditions of this study, no association was found between hepatic function alterations and short-term TPN as well as with bag light exposure in neonates.
Type:
info:eu-repo/semantics/conferenceObject
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Description:
LB003-MON; Abstracts of the 31st ESPEN Congress Vienna, Austria 29 August–1 September 2009
ISSN:
0261-5614

Full metadata record

DC FieldValue Language
dc.contributor.authorFerreyra, M.E.es_PE
dc.contributor.authorOcaña, M.C.es_PE
dc.contributor.authorBullón, E.N.es_PE
dc.creatorUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.date.accessioned2015-03-23T22:44:27Zes_PE
dc.date.available2015-03-23T22:44:27Zes_PE
dc.date.issued2015-03-23es_PE
dc.identifier.citationFerreyra ME, Ocaha MC, Bullôn EN. Lb003-Mon Assessment With Liver Function Tests and Hydroperoxides in Short-Term Very-Low-Birth-Weight Neonatal Parenteral Nutrition. Clin Nutr Suppl [Internet]. 2011;6(1):216. Available from: http://hdl.handle.net/10757/347040es_PE
dc.identifier.issn0261-5614es_PE
dc.identifier.urihttp://hdl.handle.net/10757/347040es_PE
dc.descriptionLB003-MONes_PE
dc.descriptionAbstracts of the 31st ESPEN Congress Vienna, Austria 29 August–1 September 2009es_PE
dc.description.abstractRationale: It has been reported that PN (parenteral nutrition) in preterm neonates may have deleterious effects on hepatic function. We also studied the influence of peroxidation in PN bags, with and without light protection. Methods: 30 neonates weighing 1000 1500 g on TPN were studied prospectively. Serum samples were taken at start and at end of PN. Peroxides from 31 bags at 0, 5, 18 and 24 hours were measured. PN samples were taken from both light protected and not light protected PN bags. Results: Patients: (1) With PN: GOT = 28.63±13.00 IU; GPT = 7.37±5.10 IU; TB = 9.03±3.40 IU; DB = 0.845 ±0.43 UI; GGT = 110.41±81.87 IU. (2) Without PN: GOT = 28.73±16.36 IU; GPT = 10.53±8.38 IU; TB = 6.36±3.91 IU; DB = 1.35±1.53 IU; GGT = 128.38±75.74 IU. Significant differences: GPT, TB and DB (p < 0.05). Peroxides in bags: light protected and not, respectively, at 0 hours: 278.01±139.92 and 299.87±166.00, at 5 hours: 142.28±117.93 and 155.11±140.81, at 18 hours 183.39±115.40 and 212.92±133.72 and at 24 hours 258.58±187.81 and 284.55±162.78. At 18 hours the difference was significant (p < 0.05). Conclusions: 1. TB and 18-hour hydroperoxides concentrations were higher in serum, with PN and in light unprotected PN bags, respectively. 2. GPT and DB serum levels were lower with PN. 3. Within the conditions of this study, no association was found between hepatic function alterations and short-term TPN as well as with bag light exposure in neonates.eng
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherElsevier B.V.es_PE
dc.relation.urlhttp://www.sciencedirect.com/science/journal/17441161/6/1es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.titleAssessment with liver function tests and hydroperoxides in short term very-lowbirth-weight neonatal parenteral nutritiones_PE
dc.typeinfo:eu-repo/semantics/conferenceObjectes_PE
dc.identifier.journalClinical Nutrition Supplementses_PE
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