Incidence of Respiratory Viruses in Peruvian Children With Acute Respiratory Infections

2.50
Hdl Handle:
http://hdl.handle.net/10757/347016
Title:
Incidence of Respiratory Viruses in Peruvian Children With Acute Respiratory Infections
Authors:
Del Valle Mendoza, Juana; Cornejo Tapia, Ángela; Weilg, Pablo; Verne, Eduardo; Nazario Fuertes, Ronald; Ugarte, Claudia; del Valle, Luis J.; Pumarola, Toma´ s
Citation:
Juana del Valle Mendoza; Angela Cornejo-Tapia; Pablo Weilg; Eduardo Verne; Ronald Nazario-Fuertes; Claudia Ugarte; Luis J. del Valle; Toma´ s Pumarola. Incidence of Respiratory Viruses in Peruvian Children With Acute Respiratory Infections. J Med Virol [Internet]. 2015;1–8. Available from: http://hdl.handle.net/10757/347016
Publisher:
John Wiley & Sons
Journal:
Journal Medical Virology (J. Med. Virol)
Issue Date:
23-Mar-2015
URI:
http://hdl.handle.net/10757/347016
DOI:
10.1002/jmv.24159
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1002/jmv.24159/abstract
Abstract:
Acute respiratory infections are responsible for high morbi–mortality in Peruvian children. However, the etiological agents are poorly identified. This study, conducted during the pandemic outbreak of H1N1 influenza in 2009, aims to determine the main etiological agents responsible for acute respiratory infections in children from Lima, Peru. Nasopharyngeal swabs collected from 717 children with acute respiratory infections between January 2009 and December 2010 were analyzed by multiplex RT-PCR for 13 respiratory viruses: influenza A, B, and C virus; parainfluenza virus (PIV) 1, 2, 3, and 4; and human respiratory syncytial virus (RSV) A and B, among others. Samples were also tested with direct fluorescent-antibodies (DFA) for six respiratory viruses. RT-PCR and DFA detected respiratory viruses in 240 (33.5%) and 85 (11.9%) cases, respectively. The most common etiological agents were RSV-A (15.3%), followed by influenza A (4.6%), PIV-1 (3.6%), and PIV-2 (1.8%). The viruses identified by DFA corresponded to RSV (5.9%) and influenza A (1.8%). Therefore, respiratory syncytial viruses (RSV) were found to be the most common etiology of acute respiratory infections. The authors suggest that active surveillance be conducted to identify the causative agents and improve clinical management, especially in the context of possible circulation of pandemic viruses
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Description:
jdelvall@upc.edu.pe
Keywords:
Respiratory viruses; Respiratory infection; Acute respiratory infections; Virus detection; Respiratory syncytial viruses; Influenza viruses
ISSN:
1096-9071

Full metadata record

DC FieldValue Language
dc.contributor.authorDel Valle Mendoza, Juanaes_PE
dc.contributor.authorCornejo Tapia, Ángelaes_PE
dc.contributor.authorWeilg, Pabloes_PE
dc.contributor.authorVerne, Eduardoes_PE
dc.contributor.authorNazario Fuertes, Ronaldes_PE
dc.contributor.authorUgarte, Claudiaes_PE
dc.contributor.authordel Valle, Luis J.es_PE
dc.contributor.authorPumarola, Toma´ ses_PE
dc.date.accessioned2015-03-23T14:57:23Zes_PE
dc.date.available2015-03-23T14:57:23Zes_PE
dc.date.issued2015-03-23es_PE
dc.identifier.citationJuana del Valle Mendoza; Angela Cornejo-Tapia; Pablo Weilg; Eduardo Verne; Ronald Nazario-Fuertes; Claudia Ugarte; Luis J. del Valle; Toma´ s Pumarola. Incidence of Respiratory Viruses in Peruvian Children With Acute Respiratory Infections. J Med Virol [Internet]. 2015;1–8. Available from: http://hdl.handle.net/10757/347016es_PE
dc.identifier.issn1096-9071es_PE
dc.identifier.doi10.1002/jmv.24159es_PE
dc.identifier.urihttp://hdl.handle.net/10757/347016es_PE
dc.descriptionjdelvall@upc.edu.pees_PE
dc.description.abstractAcute respiratory infections are responsible for high morbi–mortality in Peruvian children. However, the etiological agents are poorly identified. This study, conducted during the pandemic outbreak of H1N1 influenza in 2009, aims to determine the main etiological agents responsible for acute respiratory infections in children from Lima, Peru. Nasopharyngeal swabs collected from 717 children with acute respiratory infections between January 2009 and December 2010 were analyzed by multiplex RT-PCR for 13 respiratory viruses: influenza A, B, and C virus; parainfluenza virus (PIV) 1, 2, 3, and 4; and human respiratory syncytial virus (RSV) A and B, among others. Samples were also tested with direct fluorescent-antibodies (DFA) for six respiratory viruses. RT-PCR and DFA detected respiratory viruses in 240 (33.5%) and 85 (11.9%) cases, respectively. The most common etiological agents were RSV-A (15.3%), followed by influenza A (4.6%), PIV-1 (3.6%), and PIV-2 (1.8%). The viruses identified by DFA corresponded to RSV (5.9%) and influenza A (1.8%). Therefore, respiratory syncytial viruses (RSV) were found to be the most common etiology of acute respiratory infections. The authors suggest that active surveillance be conducted to identify the causative agents and improve clinical management, especially in the context of possible circulation of pandemic viruseseng
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherJohn Wiley & Sonses_PE
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1002/jmv.24159/abstractes_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subjectRespiratory viruseses_PE
dc.subjectRespiratory infectiones_PE
dc.subjectAcute respiratory infectionses_PE
dc.subjectVirus detectiones_PE
dc.subjectRespiratory syncytial viruseses_PE
dc.subjectInfluenza viruseses_PE
dc.titleIncidence of Respiratory Viruses in Peruvian Children With Acute Respiratory Infectionses_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.identifier.journalJournal Medical Virology (J. Med. Virol)es_PE
dc.description.fundingThis work has been partially supported by Programa de Ciencia y Tecnologı´a (Grant FINCyT- PIN- 2008), Peru. LJdV is in debt to support from the Generalitat de Catalunya (2009SGR1208).eng
dc.description.peer-reviewRevisión por pareses_PE
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