Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes

2.50
Hdl Handle:
http://hdl.handle.net/10757/335866
Title:
Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes
Authors:
Silva Caso, Wilmer; Olivera Irazábal, Miluska; León Álvarez, Pedro; Del Valle, Luis J.; Díaz Estacio, Sonia; Vargas, Martha; Ruiz, Joaquim; Bermúdez García, Alejandro; Del Valle Mendoza, Juana
Citation:
1. Silva-Caso W, Olivera-Irazábal M, León-Álvarez P, del Valle LJ, Díaz-Estacio S, Vargas M, et al. Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes. Asian Pacific Journal of Tropical Medicine. septiembre de 2014;7, Supplement 1:S121-6.
Publisher:
Elsevier B.V.
Issue Date:
20-Nov-2014
URI:
http://hdl.handle.net/10757/335866
DOI:
10.1016/S1995-7645(14)60217-0
Additional Links:
http://www.sciencedirect.com/science/article/pii/S1995764514602170
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Description:
Objective: To detect the most prevalent human papillomavirus (HPV) genotypes samples of asymptomatic Peruvian women by analyzing the correlation betwe ienn c Pearvpiacnailc somlaeoaur (PAP)-stained cervical tests and PCR-sequencing. Methods: A total of 254 women attending routine gynecological examinations were included in pthaitsh ostluogdiys.t Tahned scalmaspsliefise dw ebrye tahnea Blyeztehde sbdya PsAysPt etmec.h HnPiqVu ea manpdli feicxaatmioinn ewda su nddoenre au msinicgr othsceo pprei mbeyr as specific for E1 region and positive specimens were confirmed by direct sequencing. Results: The prevalence of HPV was investigated in 254 cervical scrape samples by PCR. PAP smear showed that 94.9% cases had normal morphology and 5.1% had an inflammatory pattern; 2p0r.e5v%a lwenert eg efonuontydp teo ibne c ionrfreeclatetido nw iwthit hH PchVa, ncgoems pinri scienrgv i2c0a dl icfyfetorelongt yg.enotypes. HPV16 was the most Conclusions: Our results suggest the HPV is very frequent even in women with negative PAP, eannddo PceCrRvi csaele smasm tpol ebs.e Itdheen tbifeicsat toiopnt ioofn t htoe HdePtVe rgmeinnoety tphee inc aaussyamtipvteo magateinc tw oofm HePnV m ianyf eaclltoiown t hine nimatpulreaml henisttaotriyo no fo tfh ea pdpisroepasreia aten dp rthope hsyulbascetqicu emnet adseuvreelso pwmheicnht omf acye rhviacvael ma adliirgencatn icmy.pact; jdelvall@upc.edu.pe
Keywords:
Human papillomavirus; Papanicolaou cervical cancer
ISSN:
1995-7645
Sponsors:
This work has been partially supported by Universidad Peruana de Ciencias Aplicadas (UPC), Instituto de Investigación Nutricional and Instituto de Investigación de Efrnomfe rtmheed pardoegsr aImnf ecciosas, Lima, Peru. JR has a fellowship I3, of the ISCIII (Grant No. CES11/012), and LJDV from the Generalitat de Catalunya (2009SGR1208).

Full metadata record

DC FieldValue Language
dc.contributor.authorSilva Caso, Wilmeres_PE
dc.contributor.authorOlivera Irazábal, Miluskaes_PE
dc.contributor.authorLeón Álvarez, Pedroes_PE
dc.contributor.authorDel Valle, Luis J.es_PE
dc.contributor.authorDíaz Estacio, Soniaes_PE
dc.contributor.authorVargas, Marthaes_PE
dc.contributor.authorRuiz, Joaquimes_PE
dc.contributor.authorBermúdez García, Alejandroes_PE
dc.contributor.authorDel Valle Mendoza, Juanaes_PE
dc.date.accessioned2014-11-21T01:26:06Z-
dc.date.available2014-11-21T01:26:06Z-
dc.date.issued2014-11-20-
dc.identifier.citation1. Silva-Caso W, Olivera-Irazábal M, León-Álvarez P, del Valle LJ, Díaz-Estacio S, Vargas M, et al. Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes. Asian Pacific Journal of Tropical Medicine. septiembre de 2014;7, Supplement 1:S121-6.es_PE
dc.identifier.issn1995-7645-
dc.identifier.doi10.1016/S1995-7645(14)60217-0es_PE
dc.identifier.urihttp://hdl.handle.net/10757/335866es_PE
dc.descriptionObjective: To detect the most prevalent human papillomavirus (HPV) genotypes samples of asymptomatic Peruvian women by analyzing the correlation betwe ienn c Pearvpiacnailc somlaeoaur (PAP)-stained cervical tests and PCR-sequencing. Methods: A total of 254 women attending routine gynecological examinations were included in pthaitsh ostluogdiys.t Tahned scalmaspsliefise dw ebrye tahnea Blyeztehde sbdya PsAysPt etmec.h HnPiqVu ea manpdli feicxaatmioinn ewda su nddoenre au msinicgr othsceo pprei mbeyr as specific for E1 region and positive specimens were confirmed by direct sequencing. Results: The prevalence of HPV was investigated in 254 cervical scrape samples by PCR. PAP smear showed that 94.9% cases had normal morphology and 5.1% had an inflammatory pattern; 2p0r.e5v%a lwenert eg efonuontydp teo ibne c ionrfreeclatetido nw iwthit hH PchVa, ncgoems pinri scienrgv i2c0a dl icfyfetorelongt yg.enotypes. HPV16 was the most Conclusions: Our results suggest the HPV is very frequent even in women with negative PAP, eannddo PceCrRvi csaele smasm tpol ebs.e Itdheen tbifeicsat toiopnt ioofn t htoe HdePtVe rgmeinnoety tphee inc aaussyamtipvteo magateinc tw oofm HePnV m ianyf eaclltoiown t hine nimatpulreaml henisttaotriyo no fo tfh ea pdpisroepasreia aten dp rthope hsyulbascetqicu emnet adseuvreelso pwmheicnht omf acye rhviacvael ma adliirgencatn icmy.pactes_PE
dc.descriptionjdelvall@upc.edu.pees_PE
dc.description.sponsorshipThis work has been partially supported by Universidad Peruana de Ciencias Aplicadas (UPC), Instituto de Investigación Nutricional and Instituto de Investigación de Efrnomfe rtmheed pardoegsr aImnf ecciosas, Lima, Peru. JR has a fellowship I3, of the ISCIII (Grant No. CES11/012), and LJDV from the Generalitat de Catalunya (2009SGR1208).es_PE
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherElsevier B.V.es_PE
dc.relation.urlhttp://www.sciencedirect.com/science/article/pii/S1995764514602170es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.subjectHuman papillomaviruses_PE
dc.subjectPapanicolaou cervical canceres_PE
dc.titleIdentification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andeses_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.description.peer-reviewRevisión por pareses_PE
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