Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes

2.50
Hdl Handle:
http://hdl.handle.net/10757/335866
Title:
Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes
Authors:
Silva Caso, Wilmer; Olivera Irazábal, Miluska; León Álvarez, Pedro; Del Valle, Luis J.; Díaz Estacio, Sonia; Vargas, Martha; Ruiz, Joaquim; Bermúdez García, Alejandro; Del Valle Mendoza, Juana
Citation:
1. Silva-Caso W, Olivera-Irazábal M, León-Álvarez P, del Valle LJ, Díaz-Estacio S, Vargas M, et al. Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes. Asian Pacific Journal of Tropical Medicine. septiembre de 2014;7, Supplement 1:S121-6.
Publisher:
Elsevier B.V.
Issue Date:
20-Nov-2014
URI:
http://hdl.handle.net/10757/335866
DOI:
10.1016/S1995-7645(14)60217-0
Additional Links:
http://www.sciencedirect.com/science/article/pii/S1995764514602170
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
Description:
Objective: To detect the most prevalent human papillomavirus (HPV) genotypes samples of asymptomatic Peruvian women by analyzing the correlation betwe ienn c Pearvpiacnailc somlaeoaur (PAP)-stained cervical tests and PCR-sequencing. Methods: A total of 254 women attending routine gynecological examinations were included in pthaitsh ostluogdiys.t Tahned scalmaspsliefise dw ebrye tahnea Blyeztehde sbdya PsAysPt etmec.h HnPiqVu ea manpdli feicxaatmioinn ewda su nddoenre au msinicgr othsceo pprei mbeyr as specific for E1 region and positive specimens were confirmed by direct sequencing. Results: The prevalence of HPV was investigated in 254 cervical scrape samples by PCR. PAP smear showed that 94.9% cases had normal morphology and 5.1% had an inflammatory pattern; 2p0r.e5v%a lwenert eg efonuontydp teo ibne c ionrfreeclatetido nw iwthit hH PchVa, ncgoems pinri scienrgv i2c0a dl icfyfetorelongt yg.enotypes. HPV16 was the most Conclusions: Our results suggest the HPV is very frequent even in women with negative PAP, eannddo PceCrRvi csaele smasm tpol ebs.e Itdheen tbifeicsat toiopnt ioofn t htoe HdePtVe rgmeinnoety tphee inc aaussyamtipvteo magateinc tw oofm HePnV m ianyf eaclltoiown t hine nimatpulreaml henisttaotriyo no fo tfh ea pdpisroepasreia aten dp rthope hsyulbascetqicu emnet adseuvreelso pwmheicnht omf acye rhviacvael ma adliirgencatn icmy.pact; jdelvall@upc.edu.pe
Keywords:
Human papillomavirus; Papanicolaou cervical cancer
ISSN:
1995-7645
Sponsors:
This work has been partially supported by Universidad Peruana de Ciencias Aplicadas (UPC), Instituto de Investigación Nutricional and Instituto de Investigación de Efrnomfe rtmheed pardoegsr aImnf ecciosas, Lima, Peru. JR has a fellowship I3, of the ISCIII (Grant No. CES11/012), and LJDV from the Generalitat de Catalunya (2009SGR1208).

Full metadata record

DC FieldValue Language
dc.contributor.authorSilva Caso, Wilmerspa
dc.contributor.authorOlivera Irazábal, Miluskaspa
dc.contributor.authorLeón Álvarez, Pedrospa
dc.contributor.authorDel Valle, Luis J.spa
dc.contributor.authorDíaz Estacio, Soniaspa
dc.contributor.authorVargas, Marthaspa
dc.contributor.authorRuiz, Joaquimspa
dc.contributor.authorBermúdez García, Alejandrospa
dc.contributor.authorDel Valle Mendoza, Juanaspa
dc.creatorUniversidad Peruana de Ciencias Aplicadas (UPC)spa
dc.date.accessioned2014-11-21T01:26:06Z-
dc.date.available2014-11-21T01:26:06Z-
dc.date.issued2014-11-20-
dc.identifier.citation1. Silva-Caso W, Olivera-Irazábal M, León-Álvarez P, del Valle LJ, Díaz-Estacio S, Vargas M, et al. Identification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andes. Asian Pacific Journal of Tropical Medicine. septiembre de 2014;7, Supplement 1:S121-6.spa
dc.identifier.issn1995-7645-
dc.identifier.doi10.1016/S1995-7645(14)60217-0spa
dc.identifier.urihttp://hdl.handle.net/10757/335866-
dc.descriptionObjective: To detect the most prevalent human papillomavirus (HPV) genotypes samples of asymptomatic Peruvian women by analyzing the correlation betwe ienn c Pearvpiacnailc somlaeoaur (PAP)-stained cervical tests and PCR-sequencing. Methods: A total of 254 women attending routine gynecological examinations were included in pthaitsh ostluogdiys.t Tahned scalmaspsliefise dw ebrye tahnea Blyeztehde sbdya PsAysPt etmec.h HnPiqVu ea manpdli feicxaatmioinn ewda su nddoenre au msinicgr othsceo pprei mbeyr as specific for E1 region and positive specimens were confirmed by direct sequencing. Results: The prevalence of HPV was investigated in 254 cervical scrape samples by PCR. PAP smear showed that 94.9% cases had normal morphology and 5.1% had an inflammatory pattern; 2p0r.e5v%a lwenert eg efonuontydp teo ibne c ionrfreeclatetido nw iwthit hH PchVa, ncgoems pinri scienrgv i2c0a dl icfyfetorelongt yg.enotypes. HPV16 was the most Conclusions: Our results suggest the HPV is very frequent even in women with negative PAP, eannddo PceCrRvi csaele smasm tpol ebs.e Itdheen tbifeicsat toiopnt ioofn t htoe HdePtVe rgmeinnoety tphee inc aaussyamtipvteo magateinc tw oofm HePnV m ianyf eaclltoiown t hine nimatpulreaml henisttaotriyo no fo tfh ea pdpisroepasreia aten dp rthope hsyulbascetqicu emnet adseuvreelso pwmheicnht omf acye rhviacvael ma adliirgencatn icmy.pactspa
dc.descriptionjdelvall@upc.edu.pespa
dc.description.sponsorshipThis work has been partially supported by Universidad Peruana de Ciencias Aplicadas (UPC), Instituto de Investigación Nutricional and Instituto de Investigación de Efrnomfe rtmheed pardoegsr aImnf ecciosas, Lima, Peru. JR has a fellowship I3, of the ISCIII (Grant No. CES11/012), and LJDV from the Generalitat de Catalunya (2009SGR1208).spa
dc.formatapplication/pdfspa
dc.language.isoengeng
dc.publisherElsevier B.V.spa
dc.relation.urlhttp://www.sciencedirect.com/science/article/pii/S1995764514602170spa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.subjectHuman papillomavirusspa
dc.subjectPapanicolaou cervical cancerspa
dc.titleIdentification of human papillomavirus as a preventive strategy for cervical cancer in asymptomatic women in the Peruvian Andesspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.description.peer-reviewRevisión por paresspa
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