High frequency of antimicrobial drug resistance of diarrheagenic Escherichia coli in infants in Peru.

2.50
Hdl Handle:
http://hdl.handle.net/10757/314286
Title:
High frequency of antimicrobial drug resistance of diarrheagenic Escherichia coli in infants in Peru.
Authors:
Ochoa, Theresa J.; Ruiz, Joaquím; Molina, Margarita; Del Valle, Luis J.; Vargas, Martha; Gil, Ana I.; Ecker, Lucie; Barletta, Francesca; Hall, Eric; Cleary, Thomas G.; Lanata, Claudio F.
Citation:
Am. J. Trop. Med. Hyg., 81(2), 2009, pp. 296–301
Publisher:
American Society of Tropical Medicine and Hygiene
Issue Date:
19-Mar-2014
URI:
http://hdl.handle.net/10757/314286
Additional Links:
http://www.ajtmh.org/content/81/2/296.abstract?sid=1c945488-ae67-4494-b908-fd35380a3709; http://www.ncbi.nlm.nih.gov/pubmed/19635887
Abstract:
Abstract. In a prospective passive diarrhea surveillance cohort study of 1,034 infants of low socioeconomic communities in Lima, Peru, we determined the prevalence and antimicrobial drug susceptibility of the diarrheagenic Escherichia coli . The prevalence of diarrheagenic E. coli was 29% (161 of 557) in children with gastroenteritis and 30% (58 of 195) in the control group without diarrhea. The most common E. coli pathogens in diarrhea were enteroaggregative E. coli (EAEC) (14%), enteropathogenic E. coli (EPEC) (7%), diffusely adherent E. coli (DAEC) (4%), and enterotoxigenic E. coli (ETEC) (4%). Diarrheagenic E. coli as a group exhibited high levels of antimicrobial drug resistance in diarrheal cases to ampicillin (85%), cotrimoxazole (79%), tetracycline (65%), and nalidixic acid (28%). Among individual E. coli groups in patients with diarrhea, DAEC and EAEC exhibited significant higher frequencies of resistance to ampicillin, cotrimoxazole, tetracycline and nalidixic acid than EPEC and ETEC. Antimicrobial drug resistance to ampicillin and cotrimoxazole were more frequent in E. coli isolated from diarrheal samples than controls, which reflected greater antibiotic exposure in patients with gastroenteritis.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
ISSN:
0002-9637

Full metadata record

DC FieldValue Language
dc.contributor.authorOchoa, Theresa J.spa
dc.contributor.authorRuiz, Joaquímspa
dc.contributor.authorMolina, Margaritaspa
dc.contributor.authorDel Valle, Luis J.spa
dc.contributor.authorVargas, Marthaspa
dc.contributor.authorGil, Ana I.spa
dc.contributor.authorEcker, Luciespa
dc.contributor.authorBarletta, Francescaspa
dc.contributor.authorHall, Ericspa
dc.contributor.authorCleary, Thomas G.spa
dc.contributor.authorLanata, Claudio F.spa
dc.date.accessioned2014-03-19T21:53:25Z-
dc.date.available2014-03-19T21:53:25Z-
dc.date.issued2014-03-19-
dc.identifier.citationAm. J. Trop. Med. Hyg., 81(2), 2009, pp. 296–301spa
dc.identifier.issn0002-9637-
dc.identifier.urihttp://hdl.handle.net/10757/314286-
dc.description.abstractAbstract. In a prospective passive diarrhea surveillance cohort study of 1,034 infants of low socioeconomic communities in Lima, Peru, we determined the prevalence and antimicrobial drug susceptibility of the diarrheagenic Escherichia coli . The prevalence of diarrheagenic E. coli was 29% (161 of 557) in children with gastroenteritis and 30% (58 of 195) in the control group without diarrhea. The most common E. coli pathogens in diarrhea were enteroaggregative E. coli (EAEC) (14%), enteropathogenic E. coli (EPEC) (7%), diffusely adherent E. coli (DAEC) (4%), and enterotoxigenic E. coli (ETEC) (4%). Diarrheagenic E. coli as a group exhibited high levels of antimicrobial drug resistance in diarrheal cases to ampicillin (85%), cotrimoxazole (79%), tetracycline (65%), and nalidixic acid (28%). Among individual E. coli groups in patients with diarrhea, DAEC and EAEC exhibited significant higher frequencies of resistance to ampicillin, cotrimoxazole, tetracycline and nalidixic acid than EPEC and ETEC. Antimicrobial drug resistance to ampicillin and cotrimoxazole were more frequent in E. coli isolated from diarrheal samples than controls, which reflected greater antibiotic exposure in patients with gastroenteritis.eng
dc.formatapplication/pdfspa
dc.language.isoengen
dc.publisherAmerican Society of Tropical Medicine and Hygienespa
dc.relation.urlhttp://www.ajtmh.org/content/81/2/296.abstract?sid=1c945488-ae67-4494-b908-fd35380a3709spa
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/19635887spa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.titleHigh frequency of antimicrobial drug resistance of diarrheagenic Escherichia coli in infants in Peru.spa
dc.typeinfo:eu-repo/semantics/articlespa
dc.description.peer-reviewRevisión por pareseng
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