High frequency of antimicrobial drug resistance of diarrheagenic Escherichia coli in infants in Peru.

2.50
Hdl Handle:
http://hdl.handle.net/10757/314286
Title:
High frequency of antimicrobial drug resistance of diarrheagenic Escherichia coli in infants in Peru.
Authors:
Ochoa, Theresa J.; Ruiz, Joaquím; Molina, Margarita; Del Valle, Luis J.; Vargas, Martha; Gil, Ana I.; Ecker, Lucie; Barletta, Francesca; Hall, Eric; Cleary, Thomas G.; Lanata, Claudio F.
Citation:
Am. J. Trop. Med. Hyg., 81(2), 2009, pp. 296–301
Publisher:
American Society of Tropical Medicine and Hygiene
Issue Date:
19-Mar-2014
URI:
http://hdl.handle.net/10757/314286
Additional Links:
http://www.ajtmh.org/content/81/2/296.abstract?sid=1c945488-ae67-4494-b908-fd35380a3709; http://www.ncbi.nlm.nih.gov/pubmed/19635887
Abstract:
Abstract. In a prospective passive diarrhea surveillance cohort study of 1,034 infants of low socioeconomic communities in Lima, Peru, we determined the prevalence and antimicrobial drug susceptibility of the diarrheagenic Escherichia coli . The prevalence of diarrheagenic E. coli was 29% (161 of 557) in children with gastroenteritis and 30% (58 of 195) in the control group without diarrhea. The most common E. coli pathogens in diarrhea were enteroaggregative E. coli (EAEC) (14%), enteropathogenic E. coli (EPEC) (7%), diffusely adherent E. coli (DAEC) (4%), and enterotoxigenic E. coli (ETEC) (4%). Diarrheagenic E. coli as a group exhibited high levels of antimicrobial drug resistance in diarrheal cases to ampicillin (85%), cotrimoxazole (79%), tetracycline (65%), and nalidixic acid (28%). Among individual E. coli groups in patients with diarrhea, DAEC and EAEC exhibited significant higher frequencies of resistance to ampicillin, cotrimoxazole, tetracycline and nalidixic acid than EPEC and ETEC. Antimicrobial drug resistance to ampicillin and cotrimoxazole were more frequent in E. coli isolated from diarrheal samples than controls, which reflected greater antibiotic exposure in patients with gastroenteritis.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng
ISSN:
0002-9637

Full metadata record

DC FieldValue Language
dc.contributor.authorOchoa, Theresa J.es_PE
dc.contributor.authorRuiz, Joaquímes_PE
dc.contributor.authorMolina, Margaritaes_PE
dc.contributor.authorDel Valle, Luis J.es_PE
dc.contributor.authorVargas, Marthaes_PE
dc.contributor.authorGil, Ana I.es_PE
dc.contributor.authorEcker, Luciees_PE
dc.contributor.authorBarletta, Francescaes_PE
dc.contributor.authorHall, Erices_PE
dc.contributor.authorCleary, Thomas G.es_PE
dc.contributor.authorLanata, Claudio F.es_PE
dc.date.accessioned2014-03-19T21:53:25Z-
dc.date.available2014-03-19T21:53:25Z-
dc.date.issued2014-03-19-
dc.identifier.citationAm. J. Trop. Med. Hyg., 81(2), 2009, pp. 296–301es_PE
dc.identifier.issn0002-9637-
dc.identifier.urihttp://hdl.handle.net/10757/314286es_PE
dc.description.abstractAbstract. In a prospective passive diarrhea surveillance cohort study of 1,034 infants of low socioeconomic communities in Lima, Peru, we determined the prevalence and antimicrobial drug susceptibility of the diarrheagenic Escherichia coli . The prevalence of diarrheagenic E. coli was 29% (161 of 557) in children with gastroenteritis and 30% (58 of 195) in the control group without diarrhea. The most common E. coli pathogens in diarrhea were enteroaggregative E. coli (EAEC) (14%), enteropathogenic E. coli (EPEC) (7%), diffusely adherent E. coli (DAEC) (4%), and enterotoxigenic E. coli (ETEC) (4%). Diarrheagenic E. coli as a group exhibited high levels of antimicrobial drug resistance in diarrheal cases to ampicillin (85%), cotrimoxazole (79%), tetracycline (65%), and nalidixic acid (28%). Among individual E. coli groups in patients with diarrhea, DAEC and EAEC exhibited significant higher frequencies of resistance to ampicillin, cotrimoxazole, tetracycline and nalidixic acid than EPEC and ETEC. Antimicrobial drug resistance to ampicillin and cotrimoxazole were more frequent in E. coli isolated from diarrheal samples than controls, which reflected greater antibiotic exposure in patients with gastroenteritis.eng
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherAmerican Society of Tropical Medicine and Hygienees_PE
dc.relation.urlhttp://www.ajtmh.org/content/81/2/296.abstract?sid=1c945488-ae67-4494-b908-fd35380a3709es_PE
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/19635887es_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.titleHigh frequency of antimicrobial drug resistance of diarrheagenic Escherichia coli in infants in Peru.es_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.description.peer-reviewRevisión por pareseng
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