Probiotics for treating persistent diarrhoea in children

2.50
Hdl Handle:
http://hdl.handle.net/10757/313797
Title:
Probiotics for treating persistent diarrhoea in children
Authors:
Bernaola Aponte, Guillermo; Alfonso Bada Mancilla, Carlos; Carreazo, Nilton Yhuri ( 0000-0002-5269-4855 ) ; Rojas Galarza, Raúl Alberto
Citation:
Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD007401
Publisher:
The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Issue Date:
7-Mar-2014
URI:
http://hdl.handle.net/10757/313797
DOI:
10.1002/14651858.CD007401.pub3
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007401.pub3/otherversions
Abstract:
Background Persistent diarrhoea (diarrhoea lasting more than 14 days) accounts for one third of all diarrhoea related deaths in developing countries in some studies. Probiotics may help treatment. Objectives To evaluate probiotics for treating persistent diarrhoea in children. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register, CENTRAL, MEDLINE, EMBASE, and LILACS. We also contacted authors of included trials and organizations working in the field, and checked reference lists. The date of the most recent search was 13 December 2012 Selection criteria Randomized controlled trials comparing a specified probiotic agent with placebo or no probiotic in children with persistent diarrhoea. Data collection and analysis Two review authors assessed the eligibility, risk of bias, extracted and analysed data. Differences were resolved by discussion. Statistical analysis were performed using the fixed-effect model and the results were expressed as mean difference (MD) for continuous outcomes with 95% confidence intervals (CI). Main results Four trials were included, with a total number of 464 participants; one trial had a low risk of bias. Meta-analysis showed that probiotics reduced the duration of persistent diarrhoea (mean difference 4.02 days, 95%CI 4.61 to 3.43 days, n = 324, two trials). Stool frequency was reduced with probiotics in two trials. One trial reported a shorter hospital stay, which was significant, but numbers were small. No adverse events were reported.
Type:
info:eu-repo/semantics/article
Rights:
info:eu-repo/semantics/openAccess
Language:
eng

Full metadata record

DC FieldValue Language
dc.contributor.authorBernaola Aponte, Guillermoes_PE
dc.contributor.authorAlfonso Bada Mancilla, Carloses_PE
dc.contributor.authorCarreazo, Nilton Yhuries_PE
dc.contributor.authorRojas Galarza, Raúl Albertoes_PE
dc.date.accessioned2014-03-07T22:06:37Zes_PE
dc.date.available2014-03-07T22:06:37Zes_PE
dc.date.issued2014-03-07es_PE
dc.identifier.citationCochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD007401es_PE
dc.identifier.doi10.1002/14651858.CD007401.pub3es_PE
dc.identifier.urihttp://hdl.handle.net/10757/313797es_PE
dc.description.abstractBackground Persistent diarrhoea (diarrhoea lasting more than 14 days) accounts for one third of all diarrhoea related deaths in developing countries in some studies. Probiotics may help treatment. Objectives To evaluate probiotics for treating persistent diarrhoea in children. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register, CENTRAL, MEDLINE, EMBASE, and LILACS. We also contacted authors of included trials and organizations working in the field, and checked reference lists. The date of the most recent search was 13 December 2012 Selection criteria Randomized controlled trials comparing a specified probiotic agent with placebo or no probiotic in children with persistent diarrhoea. Data collection and analysis Two review authors assessed the eligibility, risk of bias, extracted and analysed data. Differences were resolved by discussion. Statistical analysis were performed using the fixed-effect model and the results were expressed as mean difference (MD) for continuous outcomes with 95% confidence intervals (CI). Main results Four trials were included, with a total number of 464 participants; one trial had a low risk of bias. Meta-analysis showed that probiotics reduced the duration of persistent diarrhoea (mean difference 4.02 days, 95%CI 4.61 to 3.43 days, n = 324, two trials). Stool frequency was reduced with probiotics in two trials. One trial reported a shorter hospital stay, which was significant, but numbers were small. No adverse events were reported.eng
dc.formatapplication/pdfes_PE
dc.language.isoenges_PE
dc.publisherThe Cochrane Collaboration. Published by John Wiley & Sons, Ltd.es_PE
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007401.pub3/otherversionses_PE
dc.rightsinfo:eu-repo/semantics/openAccesses_PE
dc.sourceUniversidad Peruana de Ciencias Aplicadas (UPC)es_PE
dc.sourceRepositorio Académico - UPCes_PE
dc.titleProbiotics for treating persistent diarrhoea in childrenes_PE
dc.typeinfo:eu-repo/semantics/articlees_PE
dc.description.peer-reviewRevisión por pareseng
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